Results 171 to 180 of about 54,036 (205)

Cynomolgus monkeys and morphine tolerance and dependence

Drug and Alcohol Dependence, 1985
Cynomolgus monkeys readily developed tolerance to and physical dependence on morphine indistinguishable from that produced by an identical dose regimen in rhesus monkeys.
M D, Aceto, L S, Harris
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Effect of neurohypophyseal hormones on morphine dependence

Psychoneuroendocrinology, 1977
Abstract (1) The development of physical dependence on morphine is facilitated in rats treated with [desglycinamide9-arginine8]-vasopressin (DG-AVP) or with oxytocin. (2) Oxytocin appeared to be more potent than DG-AVP. (3) The essential elements of vasopressin and oxytocin required for facilitating morphine tolerance and physical dependence, are ...
J M, van Ree, D, de Wied
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Prolyl-leucyl-glycinamide (PLG) facilitates morphine dependence

Life Sciences, 1976
Abstract The development of physical dependence to morphine is facilitated in rats treated with [desglycinamide (9), arginine (8)] -vasopressin (DG-AVP) or with oxytocin. Oxytocin appeared to be more potent than DG-AVP. The essential elements of vasopressin and oxytocin required for facilitating morphine tolerance and physical dependence, are located
J M, van Ree, D, de Wied
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Acute physical dependence upon morphine in rats

Behavioral Biology, 1973
An investigation was made to determine if physical dependence would develop after a small number of large intravenous injections of morphine. Six rats, given 150 mg/kg injections 8 hr apart for 2 days and then allowed to withdraw, exhibited a mean of 90% of the abstinence symptoms measured.
W R, Coussens, W F, Crowder, S G, Smith
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Separation of Morphine Analgesia from Physical Dependence

Science, 1984
Intravenous infusion of morphine sulfate in rats for 24 hours produced marked opioid dependence, manifested by a series of well-documented signs appearing after injection of the opiate antagonist naloxone. Treatment of rats with naloxonazine significantly reduced the analgesia associated with the morphine infusions for more than 24 hours.
G S, Ling, J M, MacLeod, S, Lee, S H, Lockhart, G W, Pasternak   +4 more
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Butorphanol precipitates abstinence in morphine dependent rats

European Journal of Pharmacology, 1989
Butorphanol precipitated a withdrawal syndrome in rats receiving continuous intracerebroventricular infusions of morphine for three days. However, the potency of butorphanol to induce defecation, urination, teeth chattering and escape behavior was one to two orders of magnitude less on a molar basis than that of naloxone.
P, Horan, I K, Ho
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[Morphine dependence and preference. (I). Morphine preference in naive and morphine-experienced rats].

Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1976
The spontnaeous morphine intake ratio (M-SIR) under free access to morphine-admixed food and quinine-admixed food conditions was measured for 3 weeks in naive and morphine-experienced rats. In the case of morphine (0.5 mg/g of food) vs. quinine (0.5 mg/g of food), naive rats gradually increased M-SIR from 17% to 77%.
S, Yanaura, E, Tagashira
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Cocaine-morphine interactions in morphine-dependent rhesus monkeys

European Journal of Pharmacology, 1990
M.D. Aceto, E.R. Bowman
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RESPONSIVITY TO NALOXONE DURING MORPHINE DEPENDENCE

Annals of the New York Academy of Sciences, 1976
E L, Way, H H, Loh
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Morphine dependence modifies macrophage eicosanoid release

Agents and Actions, 1988
G R, Elliott, M J, van Batenburg, M R, Dzoljic   +2 more
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