Results 181 to 190 of about 24,480 (215)
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Locomotor activity in morphine-dependent and post-dependent rats
Pharmacology Biochemistry and Behavior, 1981The effects of morphine and naloxone were compared on the locomotor activity of nondependent, morphine-dependent, and post-dependent rats. Dependence was induced and maintained for 30 weeks by scheduled access to 0.05% morphine solution for 10 min every 6 hr.
L S, Brady, S G, Holtzman
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European Journal of Pharmacology, 2015
Previous studies have indicated that voluntary exercise decreases the severity of the anxiogenic-like behaviors in both morphine-dependent and withdrawn rats. This study examined the effects of regular swimming exercise during the development of dependency and spontaneous morphine withdrawal on the anxiety-depression profile and voluntary morphine ...
Atefeh, Fadaei +2 more
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Previous studies have indicated that voluntary exercise decreases the severity of the anxiogenic-like behaviors in both morphine-dependent and withdrawn rats. This study examined the effects of regular swimming exercise during the development of dependency and spontaneous morphine withdrawal on the anxiety-depression profile and voluntary morphine ...
Atefeh, Fadaei +2 more
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Voluntary morphine ingestion, morphine dependence, and recovery from withdrawal signs
Pharmacology Biochemistry and Behavior, 1975We are reporting on conditions (without forced drinking or premedications) where rats voluntarily drink high quantities of sucrose-morphine solutions in preference to water. The volume ingested is inversely related to the morphine concentration in the liquid. The morphine antagonist, nalorphine, produced a clear set of opiate withdrawal signs in these (
K A, Khavari +3 more
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Bulletin of Experimental Biology and Medicine, 2003
We studied the effect of potentiated antibodies to morphine (10(-100) wt %) on self-stimulation of the lateral hypothalamus and behavioral reactions reflecting the severity of withdrawal syndrome in rats with morphine dependence. Repeated treatment with potentiated antibodies to morphine increased the rate of self-stimulation, suppressed active ...
T M, Vorob'eva +6 more
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We studied the effect of potentiated antibodies to morphine (10(-100) wt %) on self-stimulation of the lateral hypothalamus and behavioral reactions reflecting the severity of withdrawal syndrome in rats with morphine dependence. Repeated treatment with potentiated antibodies to morphine increased the rate of self-stimulation, suppressed active ...
T M, Vorob'eva +6 more
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Carbamazepine potentiates morphine analgesia on postoperative pain in morphine-dependent rats
European Journal of Pharmacology, 2012Postoperative pain and its control remain one of the most important issues in the field of surgery and health care systems. Morphine is a potent and effective analgesic, but substance abuse patients can manifest cross-tolerance to it, making it difficult to satisfy their analgesic/anesthetic requirements.
Kobra, Naseri +3 more
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Tolerance-dependence and serum elimination of morphine in rats implanted with morphine pellets
General Pharmacology: The Vascular System, 19911. In order to determine whether the degree of tolerance to and physical dependence on morphine induced by pellet implantation procedure in the rat depends on the dose used and the kinetic parameters, the effect of implantation of different number of pellets on tolerance-dependence and elimination kinetics of morphine from serum was determined. 2. Male
H N, Bhargava, V M, Villar
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Brain Research, 1976
The effects of microelectrophoretically administered morphine, naloxone, levorphanol and dextrorphan have been investigated on Renshaw cells and interneurones in the spinal cord of morphine-dependent and non-dependent anaesthetized rats. Morphine excited cholinoceptive neurones and enhanced the excitatory actins of acetylcholine and L-glutamate.
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The effects of microelectrophoretically administered morphine, naloxone, levorphanol and dextrorphan have been investigated on Renshaw cells and interneurones in the spinal cord of morphine-dependent and non-dependent anaesthetized rats. Morphine excited cholinoceptive neurones and enhanced the excitatory actins of acetylcholine and L-glutamate.
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MORPHINE PHYSICAL DEPENDENCE IN THE DOG
The Journal of Pharmacology and Experimental Therapeutics, 1974W R, Martin +4 more
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Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1976
The spontnaeous morphine intake ratio (M-SIR) under free access to morphine-admixed food and quinine-admixed food conditions was measured for 3 weeks in naive and morphine-experienced rats. In the case of morphine (0.5 mg/g of food) vs. quinine (0.5 mg/g of food), naive rats gradually increased M-SIR from 17% to 77%.
S, Yanaura, E, Tagashira
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The spontnaeous morphine intake ratio (M-SIR) under free access to morphine-admixed food and quinine-admixed food conditions was measured for 3 weeks in naive and morphine-experienced rats. In the case of morphine (0.5 mg/g of food) vs. quinine (0.5 mg/g of food), naive rats gradually increased M-SIR from 17% to 77%.
S, Yanaura, E, Tagashira
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ACETYLCHOLINESTERASE INHIBITION AND MORPHINE EFFECTS IN MORPHINE TOLERANT AND DEPENDENT MICE
The Journal of Pharmacology and Experimental Therapeutics, 1972H N, Bhargava, E L, Way
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