Results 101 to 110 of about 10,950 (303)

Pharmacological treatment strategies to manage precipitated withdrawal following the administration of buprenorphine in opioid use disorder: A systematic review

Addiction, EarlyView.
Abstract Background and aims There has been limited evidence synthesis examining the treatment of buprenorphine precipitated opioid withdrawal (BPOW). We aimed to conduct the first systematic review to assess the clinical utility of any pharmacological intervention in the management of BPOW.
Emmert Roberts, Nicola Kalk, John Strang
wiley   +1 more source

A Longitudinal Assessment of Endometriosis Patients Prescribed Cannabis‐Based Medicinal Products: A Case Series From the UK Medical Cannabis Registry

Australian and New Zealand Journal of Obstetrics and Gynaecology, EarlyView.
ABSTRACT Background Although there is growing evidence supporting the use of cannabis‐based medicinal products (CBMPs) for the management of chronic pain, there is a paucity of data on their effect on endometriosis‐associated chronic pain. Aims This study aimed to perform an analysis of pain‐specific and general health‐related quality of life (HRQoL ...
Sara Getter, Simon Erridge, John Warner‐Levy, Evonne Clarke, Katy McLachlan, Ross Coomber, Shelley Barnes, Alia Darweish Medniuk, Rahul Guru, Wendy Holden, Mohammed Sajad, Robert Searle, Azfer Usmani, Sanjay Varma, James J. Rucker, Michael Platt, Mikael H. Sodergren   +16 more
wiley   +1 more source

Patient‐reported outcomes, postoperative pain and pain relief after day‐case surgery (POPPY): baseline data from day surgery practice in the UK

Anaesthesia, EarlyView.
Summary Introduction Most patients undergoing elective surgery in the UK are discharged from hospital on the same day. Despite this, there is a lack of UK patient‐centred outcome measures relating to quality of recovery, pain and analgesic use. The POPPY study was a UK‐wide prospective, observational study measuring short‐ and longer‐term patient ...
Martha Belete, Adam B. Brayne, Harriet Daykin, Matthew Everson, William M. Hare, Anna Ratcliffe, Lexy Sorrell, Mark Rockett, on behalf of the Research and Audit Federation of Trainees   +8 more
wiley   +1 more source

Synthesis of B/C trans-Fused Morphine Structures. VI. Mass Spectrum, Optical Rotatory Dispersion and Circular Dichroism of B/C trans-Morphine Derivatives

, 1973
H. INOUE, Mikio Takeda, Hiroshi Kugita
openalex   +2 more sources

Opioid‐free vs. opioid‐inclusive anaesthesia with or without regional anaesthesia for postoperative pain: a systematic review with network meta‐analysis of randomised controlled trials

Anaesthesia, EarlyView.
Summary Introduction Concerns about opioid‐related adverse effects have increased interest in opioid‐free anaesthesia, but the benefits compared with opioid‐inclusive techniques, especially in the presence of regional anaesthesia, remain uncertain. Methods We undertook a systematic review with a network meta‐analysis of randomised controlled trials ...
Clístenes C. de Carvalho, Kariem El‐Boghdadly, Idrys H. L. Guedes, Maria Vitória M. Dantas, Danusa P. B. Tomé, Isabella B. Ramos, Clarissa S. H. Gomes, Guilherme K. P. A. Alves, Arthur P. Bezerra, Jayme M. Santos Neto, Jaideep J. Pandit, Leandro G. Braz   +11 more
wiley   +1 more source

SYNTHESIS AND PHARMACOLOGICAL EVALUATION OF N-METHYL PIPERIDINE ANALGESICS [PDF]

Journal of Sciences, Islamic Republic of Iran, 1993
Pain is probably the immediate stimulus for more visits to the Physician's office than all other complaints combined. Since pain serves as an alert to injury, it is often the first harbinger of disease.
doaj  

Economic evidence for licensed ready‐to‐administer intravenous products compared with standard vials and ampoules: a systematic review

Anaesthesia, EarlyView.
Summary Introduction Injectable medicines represent a significant proportion of the annual medicines expenditure of the NHS in England, totalling £7 billion ($9.4 billion, €8.0 billion) in 2023. This represents approximately 70% of hospital medicines spending and includes essential treatments delivered at the point of care, such as chemotherapy ...
Suzanne Al‐Rawi, Matthew Greening, Sue Ladds   +2 more
wiley   +1 more source

Studies Aimed at the Synthesis of Morphine, IV: A New Approach to N‐Norreticuline Derivatives from Homoveratronitrile

, 1981
Csaba Szántay, Gábor Dörnyei, Gábor Blaskó, M. BARCZAI‐BEKE, Péter Péchy   +4 more
openalex   +2 more sources

Phenotype, Management, and Outcomes in Paediatric Acute Pancreatitis: A Real‐Life Cross‐Sectional Study

Acta Paediatrica, EarlyView.
ABSTRACT Aim Limited Canadian data on paediatric acute pancreatitis exist. A meta‐analysis of 48 studies reported equal prevalence of acute pancreatitis among various aetiologies, with rates of severe acute pancreatitis at 13.7% in North America.
Catherine Korman, Doha Elhaoua, Sarah Blain, Thomas Li, Mariam Mohamed, Alessandro David, Colette Deslandres, Ugur Halac, Martha Dirks, Kelly Grzywacz, Michel Lallier, Fernando Alvarez, Prévost Jantchou   +12 more
wiley   +1 more source

Novel 1-(1-Arylimiazolin-2-Yl)-3-Arylalkilurea Derivatives with Modulatory Activity on Opioid MOP Receptors

Molecules
μ-opioid receptor ligands such as morphine and fentanyl are the most known and potent painkillers. However, the severe side effects seen with their use significantly limit their widespread use.
Dominik Straszak, Sylwia Woźniak, Agata Siwek, Monika Głuch-Lutwin, Marcin Kołaczkowski, Aldona Pietrzak, Bartłomiej Drop, Dariusz Matosiuk   +7 more
doaj   +1 more source