Results 121 to 130 of about 11,589 (292)

Comparing leukocyte‐ and thrombocyte‐rich fibrin and autologous grafts for the treatment of experimentally induced wounds in the tarsometatarsus of chickens

Veterinary Record, EarlyView.
Abstract Background Managing open wounds in birds is challenging. This study compared leukocyte‐ and thrombocyte‐rich fibrin (L‐TRF) and autologous grafts for treating wounds in the tarsometatarsus of chickens. Methods Full‐thickness wounds were experimentally induced in the tarsometatarsus of 23 healthy adult chickens.
Vivian Ferreira Rech, Sheila Canevese Rahal, Renata Dalcol Mazaro, Luna Scarpari Rolim, Guilherme Rech Cassanego, Matheus Yuri Dos Santos, Rafael Almeida Fighera   +6 more
wiley   +1 more source

Computational logP Calculations and Determination of Lipophilicity Values of Fluorinated Morphine Derivatives

The addictive effect of opioids impacted 60 million people globally in 2023. This opioid crisis necessitates the development of opioid derivatives that maintain analgesic efficacy while minimizing addictive effects from opioid use.
Chen, Emily, Vu, Allison, Romano, Mirabella   +2 more
core  

Biochemical and pharmacological studies of morphine-6-glucuronide and related compounds [PDF]

, 1994
Morphine-6-glucuronide is a minor metabolite. representing 5% of an administered dose of morphine. The metabolite has analgesic activity exceeding that of morphine and may contribute to analgesia following morphine administration.
Jason Lewis Martin (7166942)
core  

Impact of general anaesthesia on immune response to first rabies vaccination in seronegative domestic cats

Veterinary Record, EarlyView.
Abstract Background Despite common concerns, evidence that anaesthesia impairs vaccine efficacy remains limited. This study assessed the impact of general anaesthesia on the immune response to rabies vaccination in cats. Methods Thirty‐five healthy female cats (6–12 months old) undergoing elective spaying were enrolled.
Pierre Bessière, Romane Breysse, Marion Chrétien, Brandon Hayes, Séverine Boullier, Anouck Labadie, Jonathan Rieder, Marine Wasniewski, Géraldine Jourdan   +8 more
wiley   +1 more source

Masculinity, Prostitution, and the Imaginary Northwest in Chinese Travel Writings About Shanxi and Western Inner Mongolia, 1920–1949

Gender &History, EarlyView.
ABSTRACT This article considers travel writings by metropolitan men in Republican China about Shanxi and western Inner Mongolia as a case study to further explore the transformations and continuities of Chinese masculinities. Drawing upon a range of popular travel narratives, it shows that so‐called “Worn‐Out Shoes (poxie)” – women perceived as ...
Amanda Zhang
wiley   +1 more source

Investigation of eosin Y as a colorimetric sensor for the detection of fentanyl hydrochloride and fentanyl freebase

Journal of Forensic Sciences, EarlyView.
Abstract The increasing prevalence of fentanyl within the illegal global drug market underscores the need for rapid, low‐cost, and straightforward detection methods. Eosin Y demonstrates a measurable color change in the presence of fentanyl, making it a promising candidate for colorimetric sensing and preliminary identification of fentanyl ...
Alan J. Zhou, Melissa M. Dixon, Brady S. Gentle, Genevieve H. Dennison, Kellie L. Tuck   +4 more
wiley   +1 more source

EVIDENCE FOR MORPHINE AND MORPHINE-LIKE ALKALOID RESPONSES RESISTANT TO NALOXONE BLOCKADE IN THE RAT VAS-DEFERENS

, 1979
The application of morphine or surrogates to the isolated rat was deferens maintained at 37.degree. C in Tyrode solution produced an increase in the electrically induced muscular twitch.
MIRANDA, H, HUIDOBRO, F, HUIDOBROTORO, JP   +2 more
core  

Synthesis and evaluation of the analgesic activity of some new isoxazolo[4,5-d]pyridazin-4(5H)-one derivatives

, 2011
Some isoxazolo[4,5-d] pyridazin4(5H)-one derivatives were synthesized and tested for their analgesic activity. The analgesic activities of the compounds were determined by hot-plate and acetic acid writhing tests using morphine and diclofenac as ...
Tan, Oya Unsal, Ozadali, Keriman, Uzbay, Tayfun, BALKAN, AYLA, Kayir, Hakan, Yesilyurt, Ozgur   +5 more
core   +1 more source

Search for Effective Antibodies to Morphine Derivatives

Journal Biomed
A scheme for immunization of goats with morphine derivatives conjugated with bovine serum albumin (BSA) is proposed. It was shown that antibodies to morphine are formed in high titers in blood serum (2×10–6) and goat milk (1×10–4). The specificity of antibodies to morphine was confirmed using ELISA and Western blot methods.
A. G. Berzina, D. K. Ismailova, D. V. Khvostov, M. A. Savina, N. N. Karkischenko   +4 more
openaire   +1 more source

Temporal and geographical patterns of nitazene detections in drug samples and biospecimens in the United States, 2019–2024

Addiction, EarlyView.
Abstract Background and aims Nitazenes are a novel subclass of synthetic opioids that have been increasingly implicated in the United States (US) overdose crisis. Despite their growing presence in the illicit drug supply, national trends have not been systematically evaluated.
David T. Zhu, Nicole D. Fitzgerald, Joseph J. Palamar, Alex J. Krotulski   +3 more
wiley   +1 more source