Results 101 to 110 of about 11,589 (292)

Effect of Intraoperative Regional Anesthesia on Postoperative Outcomes in Pediatric Cardiac Surgery—A Systematic Review of Randomized Controlled Trials

open access: yesPediatric Anesthesia, EarlyView.
ABSTRACT Objective To conduct a meta‐analysis of postoperative outcomes following the use of regional anesthesia in pediatric cardiac surgery. Data Sources We searched PubMed (MEDLINE), Web of Science, CINAHL, CENTRAL, and Scopus in December 2024 (PROSPERO: CRD420025635423; registered January 2025).
Katariina Hiisivuori   +3 more
wiley   +1 more source

Anionic polycyclization : towards the total synthesis of indole alkaloids and morphine derivatives

open access: yes, 2014
Aspidosperma alkaloids receive special attention of synthetic chemists due to their enticing structures and a wide range of remarkable biological activities.
Horiuchi, Akina
core  

Synthesis and Evaluation of a Series of 3,4,5-Trimethoxycinnamic Acid Derivatives as Potential Antinarcotic Agents

open access: yes, 2020
A series of 3,4,5-trimethoxycinnamic acid derivatives was prepared and evaluated for antinarcotic effects on morphine dependence in mice and binding affinities on serotonergic receptors.
정재철, 오세관
core   +1 more source

Plasma Lidocaine Concentrations During Intravenous Lidocaine Infusion Therapy in the Pediatric Population—A Scoping Review

open access: yesPediatric Anesthesia, EarlyView.
ABSTRACT Background Intravenous lidocaine therapy (IVLT) is often used in perioperative multimodal analgesia due to its analgesic, anti‐hyperalgesic, and anti‐inflammatory effects. In adults, IVLT doses of 1–2 mg/kg/h produce plasma concentrations of 1–2 μg/mL, within the presumed therapeutic range of 1–5 μg/mL.
McKenna Postles   +3 more
wiley   +1 more source

Characterization of human and bovine phosphatidylethanolamine-binding protein (PEBP/RKIP) interactions with morphine and morphine-glucuronides determined by noncovalent mass spectrometry

open access: yes, 2009
International audienceThe phosphatidylethanolamine-binding protein (PEBP/RKIP), initially found to bind phosphatidylethanolamine (PE), has been shown to be associated with morphine derivatives.
Laux, Alexis   +12 more
core  

Association of Preoperative Inflammatory Markers With Preoperative Anxiety and Emergence Agitation in Children

open access: yesPediatric Anesthesia, EarlyView.
ABSTRACT Introduction Emergence agitation (EA) is a postoperative neurobehavioral complication characterized by a transient disturbance in cognition and perception following anesthesia. Neuroinflammation is thought to play a central role in its pathophysiology.
Nezahat Merve Ata Soylu   +6 more
wiley   +1 more source

Intraoperative Cardiac Events During Pediatric Cardiac Magnetic Resonance Imaging Under Anesthesia: A Retrospective Cohort Study

open access: yesPediatric Anesthesia, EarlyView.
ABSTRACT Background Children with congenital heart disease (CHD) frequently undergo cardiac magnetic resonance imaging (MRI) under anesthesia. Although these procedures lack surgical stimulus, patients remain physiologically vulnerable, and the incidence of perioperative cardiovascular instability in this setting is poorly defined.
Theodora Wingert   +8 more
wiley   +1 more source

Medication prescription patterns in cancer rehabilitation physiatry outpatients: A multicenter retrospective study

open access: yesPM&R, EarlyView.
Abstract Background and Objective Previous work from this dataset found 45% prescribing frequency of any medications (35.1%, 33.5%, and 56.8% at institutions 1, 2, and 3 respectively), without significant difference between in‐person and telemedicine.
Matthew Chen   +7 more
wiley   +1 more source

The Distribution of opiates, cocaine and their metabolites in skeletal muscle tissue and vitreous humour as an aid to post-mortem toxicological interpretation.

open access: yes
Post-mortem blood drug concentrations vary greatly and as a consequence of post-mortem change and redistribution may not reflect the concentration at the time of death.
Rees, Kelly-Ann
core  

Asymmetric Total Synthesis of (-)-Octahydro-1h- Benzofuro 3,2-E Isoquinoline, a Partial Structure of Morphine

open access: yes, 2009
Octahydro-1H-benzofuro[3,2-e]isoquinolines, which possess the ACNO partial structure of morphine, displayed potent oral analgesic and narcotic-antagonism activity.
Hsin, Ling-Wei; Chen, Chien-Wei; Chang, Li-Te   +1 more
core   +1 more source

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