Results 81 to 90 of about 11,589 (292)

Opium trade and use during the Late Bronze Age: Organic residue analysis of ceramic vessels from the burials of Tel Yehud, Israel

open access: yesArchaeometry, EarlyView., 2022
Abstract Organic residue analysis was conducted on various vessels from burials at Tel Yehud, Israel. The analyses led to new reliable evidence for the presence of opioid alkaloids and their decomposition products. This research revitalizes a decades‐old discussion on the presence and function of the opium trade across a cultural region of utmost ...
Vanessa Linares   +5 more
wiley   +1 more source

Transdermal delivery of morphine derivatives : a qualitative structure-in vitro permeability relationship

open access: yes, 2014
The in vitro permeability of six different morphine derivatives (morphine, codeine, hydromorphone, hydrocodone, oxymorphone, oxycodone) through human epidermis was studied to elucidate the influence of three different substituents, namely the methoxyl ...
C. Matera   +4 more
core  

Análise comportamental e farmacológica da nocicepção cutânea e articular induzida por formalina [PDF]

open access: yes, 2014
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-Graduação em Farmacologia, Florianópolis, 2014.A dor clínica possui um caráter multidimensional, mas a sua dimensão afetiva é pouco explorada ...
Vanz, Felipe
core  

An Emerging New Paradigm in Opioid Withdrawal: A Critical Role for Glia-Neuron Signaling in the Periaqueductal Gray

open access: yesThe Scientific World Journal, 2012
The chronic use of opiates (i.e., narcotics such as the natural derivatives of opium including morphine or codeine) or opioids (i.e., semisynthetic derivatives of opium and other molecules that activate opioid receptors) induces dependence, which is ...
Handong Ouyang   +5 more
doaj   +1 more source

Krokodil—Morphine’s Deadly Derivative

open access: yesJournal of Student Research, 2015
Graphically publicized in the media, the use of Krokodil, a heroin-like morphine derivative, has grown in Eastern Europe the last decade.  The popularity of the injectable drug has grown in part due to its inexpensive and simple manufacturing process through the use of codeine tablets.
openaire   +2 more sources

Effectiveness of immersive virtual reality‐based interventions for alleviating peri‐ and post‐procedural pain and anxiety in gynecologic settings: A systematic review and meta‐analysis of randomized controlled trials

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Background Non‐pharmacological and complementary therapeutic, notably immersive virtual reality‐based interventions (IVR), could alleviate pain and anxiety associated with gynecologic procedures. Objective To evaluate the effectiveness of IVR in reducing peri‐ and post‐procedural pain and anxiety in gynecologic procedures.
Cristina González‐Lara   +4 more
wiley   +1 more source

Sexual dimorphism in hormone–gut microbiome associations across reproductive states in wild giant pandas

open access: yesiMetaOmics, EarlyView.
Gut microbiota–host endocrine interactions in wild mammals remain poorly understood. Giant pandas experience seasonal dietary shifts and constrained annual reproduction, offering an ideal model to investigate microbiome–endocrine coupling. We integrated fecal hormone profiling, microsatellite‐based individual identification, and gut microbiome ...
Qinlong Dai   +10 more
wiley   +1 more source

Transdermal delivery of morphine derivatives : a qualitative structure/in vitro permeability relationship

open access: yes, 2013
Purpose The in vitro permeability of six different morphine derivatives (morphine, codeine, hydromorphone, hydrocodone, oxymorphone, oxycodone) through human epidermis was studied to elucidate the influence of three different substituents, namely the ...
C. Matera   +4 more
core  

The development and applications of polyclonal and monoclonal antibodies for the detection of illicit drugs in saliva samples [PDF]

open access: yes, 2002
Anti-tetrahydrocannabinol (THC), anti-cocaine and anti-morphine polyclonal antibodies were produced. These antibodies were successfully applied to an ELISA format for the detection of THC, cocaine, and morphine in saliva samples. Monoclonal antibodies
Fanning, Lorna M.
core  

Implantable drug delivery system: Frontiers of medicine‐engineering interdisciplinary

open access: yesInterdisciplinary Medicine, EarlyView.
This review systematically summarizes the driving mechanisms of implantable on‐demand drug delivery systems (IDDS), including endogenous, exogenous, and closed‐loop strategies. It highlights the pivotal roles of flexible electronics and miniaturization in enhancing the tissue conformity and spatial adaptability.
Yu Zeng   +9 more
wiley   +1 more source

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