Results 71 to 80 of about 51,793 (252)

A Theory of Natural Addiction [PDF]

open access: yes, 2007
Economic theories of rational addiction aim to describe consumer behavior in the presence of habit-forming goods. We provide a biological foundation for this body of work by formally specifying conditions under which it is optimal to form a habit.
Ainslie   +102 more
core   +1 more source

Physicians' hybridisation with accounting in public hospitals

open access: yesAccounting &Finance, EarlyView.
Abstract Accounting information has become an integral part of management tools in public hospitals. Following COVID‐19, the crisis in the supply chain and the war in Ukraine severely impacted the financing of public hospitals. In response to this multi‐crisis environment, physicians have increased their awareness on an efficient use of scarce ...
Susana Gago‐Rodríguez   +2 more
wiley   +1 more source

Endoplasmic Reticulum Stress in Spinal Cord Contributes to the Development of Morphine Tolerance

open access: yesFrontiers in Molecular Neuroscience, 2018
Morphine tolerance remains an intractable problem, which hinders its prolonged use in clinical practice. Endoplasmic reticulum (ER) stress has been proved to play a fundamental role in the pathogenesis of Alzheimer’s disease, diabetes, atherosclerosis ...
Daiqiang Liu   +11 more
doaj   +1 more source

Sumatriptan effects on morphine-induced antinociceptive tolerance and physical dependence: The role of nitric oxide [PDF]

open access: yes, 2018
Sumatriptan, a 5HT (5-hydroxytryptamine)1B/1D receptor agonist, showed neuroprotection in different studies. The aim of the present study was to investigate the effect of sumatriptan on morphine-induced antinociceptive tolerance and physical dependence.
Akbarian, Reihaneh.   +8 more
core  

Pre‑operative pain sensitivity : a prediction of post‑operative outcome in the obstetric population [PDF]

open access: yes, 2013
Context: Experimental assessments can determine pain threshold and tolerance, which mirror sensitivity to pain. This, in turn, influences the post‑operative experience.
Azzopardi, Lilian M.   +6 more
core   +2 more sources

Addiction‐related problems in Japan: A regional perspective

open access: yesAddiction, EarlyView.
Abstract Japan's addiction landscape appears paradoxical. The lifetime use of illicit drugs is among the lowest in Organisation for Economic Cooperation and Development countries, but harm from alcohol, tobacco, and gambling ranks among the world's highest.
Soichiro Ide   +19 more
wiley   +1 more source

The Regulatory Mechanisms and Therapeutic Potential of MicroRNAs: From Chronic Pain to Morphine Tolerance

open access: yesFrontiers in Molecular Neuroscience, 2018
Chronic pain, including cancer-related pain, is a pain condition often caused by inflammation or dysfunctional nerves. Chronic pain treatment poses a significant health care challenge, where opioids especially morphine are widely used and patients often ...
Zhao Dai   +5 more
doaj   +1 more source

Nitrous Oxide: Mechanism of Its Antinociceptive Action [PDF]

open access: yes, 1995
Nitrous oxide (N2O) is an anesthetic gas known to produce an analgesic effect at sub-anesthetic concentrations. This analgesic property of N2O can be clinically exploited in a broad range of conditions where pain relief is indicated.
Quock, Raymond M., Vaughn, Linda K.
core   +1 more source

Inhibition of activity of GABA transporter GAT1 by δ-opioid receptor [PDF]

open access: yes, 2012
Analgesia is a well-documented effect of acupuncture. A critical role in pain sensation plays the nervous system, including the GABAergic system and opioid receptor (OR) activation.
Fucke, Thomas   +7 more
core   +2 more sources

Rare but relevant: Ibogaine and cardiovascular complications—prolonged QT interval and ventricular arrhythmias

open access: yesAddiction, EarlyView.
Abstract Revived interest in psychedelic‐assisted therapies has also renewed focus on ibogaine, a psychoactive alkaloid, for its notable anti‐addictive potential. Evidence from observational, open‐label, and limited randomized placebo‐controlled trials indicates that ibogaine and its metabolite noribogaine reduce craving and withdrawal symptoms in ...
Tibor Markus Brunt
wiley   +1 more source

Home - About - Disclaimer - Privacy