Results 51 to 60 of about 254,310 (345)

Metastasising ameloblastoma or ameloblastic carcinoma? A case report with mutation analyses

BMC Oral Health, 2023
Background Ameloblastic carcinoma and metastasising ameloblastoma are rare epithelial odontogenic tumours with aggressive features. Distinguishing between these two lesions is often clinically difficult but necessary to predict tumour behaviour or to ...
Pavel Hurník, Barbora Moldovan Putnová, Tereza Ševčíková, Eva Hrubá, Iveta Putnová, Josef Škarda, Martin Havel, Oldřich Res, Jakub Cvek, Marcela Buchtová, Jan Štembírek   +10 more
doaj   +1 more source

Pathway Analyses of Inherited Neuropathies Identify Putative Common Mechanisms of Axon Degeneration

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Inherited neuropathies (IN) are associated with over 100 different genetic mutations presenting with a variety of phenotypes. This complexity suggests multiple pathways may converge onto a limited number of downstream pathways to effect axonal injury.
Christopher R. Cashman, Craig Blackstone, Reza Sadjadi   +2 more
wiley   +1 more source

Eph-ephrin signaling couples endothelial cell sorting and arterial specification

Nature Communications
Cell segregation allows the compartmentalization of cells with similar fates during morphogenesis, which can be enhanced by cell fate plasticity in response to local molecular and biomechanical cues.
Jonas Stewen, Kai Kruse, Anca T. Godoi-Filip, Zenia, Hyun-Woo Jeong, Susanne Adams, Frank Berkenfeld, Martin Stehling, Kristy Red-Horse, Ralf H. Adams, Mara E. Pitulescu   +10 more
doaj   +1 more source

Discrimination of Brazilian propolis according to the seasoning using chemometrics and machine learning based on UV-Vis scanning data

Journal of Integrative Bioinformatics, 2015
Propolis is a chemically complex biomass produced by honeybees (Apis mellifera) from plant resins added of salivary enzymes, beeswax, and pollen. The biological activities described for propolis were also identified for donor plant’s resin, but a big ...
Tomazzoli Maíra M., Pai Neto Remi D., Moresco Rodolfo, Westphal Larissa, Zeggio Amelia R. S., Specht Leandro, Costa Christopher, Rocha Miguel, Maraschin Marcelo   +8 more
doaj   +1 more source

Forskolin Enhances Urokinase Plasminogen Activator Secretion and Angiogenic Activity of Xeno‐Free Cultures of Human Adipose Tissue‐Derived Stem Cells

Advanced Biology, EarlyView.
The regenerative potential of adipose tissue‐derived stem cells can be enhanced through chemical stimulation in vitro. A short stimulation protocol using forskolin, either alone or in combination with other growth factors, under xeno‐free conditions enhanced the pro‐angiogenic responses in human ASCs.
Maria Vittoria Giraudo, Anne Therese Lauvrud, Rebecca Wiberg, Maria Brohlin, Gustav Andersson, Paul J Kingham   +5 more
wiley   +1 more source

Retrotransposon Expression Is Upregulated in Adulthood and Suppressed during Regeneration of the Limb in the Axolotl (Ambystoma mexicanum)

Advanced Biology, EarlyView.
The axolotl's remarkable regenerative abilities decline with age, the causes may include the numerous repetitive elements within its genome. This study uncovers how Ty3 retrotransposons and coexpression networks involving muscle and immune pathways respond to aging and regeneration, suggesting that transposons respond to physiological shifts and may ...
Samuel Ruiz‐Pérez, Nicolás Alcaraz, Karla Torres‐Arciga, José Antonio Ocampo‐Cervantes, Alejandra Cervera, Clementina Castro‐Hernández, Cynthia Gabriela Sámano‐Salazar, Ernesto Soto‐Reyes, Rodrigo González‐Barrios   +8 more
wiley   +1 more source

Regulation of Cdc42 and its effectors in epithelial morphogenesis

Journal of Cell Science, 2019
Cdc42 – a member of the small Rho GTPase family – regulates cell polarity across organisms from yeast to humans. It is an essential regulator of polarized morphogenesis in epithelial cells, through coordination of apical membrane morphogenesis, lumen ...
F. Pichaud, Rhian F. Walther, Francisca Nunes de Almeida   +2 more
semanticscholar   +1 more source

Current and Future Cornea Chip Models for Advancing Ophthalmic Research and Therapeutics

Advanced Biology, EarlyView.
This review analyzes cornea chip technology as an innovative solution to corneal blindness and tissue scarcity. The examination encompasses recent developments in biomaterial design and fabrication methods replicating corneal architecture, highlighting applications in drug screening and disease modeling while addressing key challenges in mimicking ...
Minju Kim, Kanghoon Choi, Amy Lin, Jungkyu Kim   +3 more
wiley   +1 more source

ELMO2 is an essential regulator of carotid artery development

Nature Communications
Engulfment and cell motility 2 (ELMO2) is a cytoskeletal adaptor protein necessary for cell migration and apoptotic cell removal. Loss-of-function mutations in ELMO2 cause intraosseous vascular malformation (VMOS), a human disease involving progressive ...
Athira Suresh, Kai Kruse, Hendrik Arf, Rodrigo Diéguez-Hurtado, Ralf H. Adams   +4 more
doaj   +1 more source

Standardised imaging pipeline for phenotyping mouse laterality defects and associated heart malformations, at multiple scales and multiple stages

Disease Models & Mechanisms, 2019
Laterality defects are developmental disorders resulting from aberrant left/right patterning. In the most severe cases, such as in heterotaxy, they are associated with complex malformations of the heart.
Audrey Desgrange, Johanna Lokmer, Carmen Marchiol, Lucile Houyel, Sigolène M. Meilhac   +4 more
doaj   +1 more source