Results 81 to 90 of about 673,537 (375)
Sox8 is essential for vertebrate gastrulation
EMBO ReportsGastrulation is a fundamental developmental process during which germ layers are formed and the body axes are defined by the precise orchestration of cell movements and fate specification. Here, we identify the SOXE transcription factor Sox8 as a pivotal
Sofia Moreira +2 more
doaj +1 more source
Disease Models & Mechanisms, 2019 Laterality defects are developmental disorders resulting from aberrant left/right patterning. In the most severe cases, such as in heterotaxy, they are associated with complex malformations of the heart.
Audrey Desgrange +4 more
doaj +1 more source
Parameter estimation and inference for stochastic reaction-diffusion systems: application to morphogenesis in D. melanogaster [PDF]
, 2010 Background: Reaction-diffusion systems are frequently used in systems biology to model developmental and signalling processes. In many applications, count numbers of the diffusing molecular species are very low, leading to the need to explicitly model ...
Dewar, M.A. +3 more
core +4 more sources
Advanced Functional Materials, EarlyView.A mechanically tunable hydrogel composed of gelatin, chondroitin sulfate and laminin promotes angiogenesis in vitro without the supplement of growth factors. Endothelial cells morphogenesis was further enhanced by medium conditioned with bioactive glass 58S‐released ions (Ca and Si), thus offering a promising strategy to vascularize 3D tissue ...
Marco Piazzoni +13 more
wiley +1 more source
Deep learning-based detection of murine congenital heart defects from µCT scans
Communications BiologyMicro-computed tomography (μCT) provides 3D images of congenital heart defects (CHD) in mice. However, diagnosing CHD from μCT scans is time-consuming and requires clinical expertise. Here, we present a deep learning approach to automatically segment and
Hoa Nguyen +7 more
doaj +1 more source
MAP7 regulates axon morphogenesis by recruiting kinesin-1 to microtubules and modulating organelle transport. [PDF]
, 2018 Neuronal cell morphogenesis depends on proper regulation of microtubule-based transport, but the underlying mechanisms are not well understood.
Ma, Le +3 more
core +1 more source
Multi-Level Modeling of Quotation Families Morphogenesis [PDF]
, 2012 This paper investigates cultural dynamics in social media by examining the proliferation and diversification of clearly-cut pieces of content: quoted texts. In line with the pioneering work of Leskovec et al. and Simmons et al.
Cointet, Jean-Philippe +2 more
core +4 more sources
Regulation of Cdc42 and its effectors in epithelial morphogenesis
Journal of Cell Science, 2019 Cdc42 – a member of the small Rho GTPase family – regulates cell polarity across organisms from yeast to humans. It is an essential regulator of polarized morphogenesis in epithelial cells, through coordination of apical membrane morphogenesis, lumen ...
F. Pichaud +2 more
semanticscholar +1 more source
Advanced Functional Materials, EarlyView.A modular biosynthetic PVA–gelatin hydrogel crosslinked via visible‐light thiol‐ene chemistry is engineered as a coating for neural electrodes. Optimizing matrix composition and mechanical properties enables the hydrogel to support astrocytic populations that guide neural differentiation and functional maturation.
Martina Genta +4 more
wiley +1 more source
A specialized bone marrow microenvironment for fetal haematopoiesis
Nature Communications, 2022 The colonization of bone marrow by haematopoietic stem and progenitor cells is critical for lifelong blood cell formation. Here the authors report distinct features of fetal bone marrow and show that artery-derived signals promote haematopoietic ...
Yang Liu +8 more
doaj +1 more source