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Genes and Function, 1997
The concept that there is a substance in bone that can induce new-bone formation has been discussed for many years. However, the credit for the discovery of bone morphogenetic protein goes to Marshall R. Urist, who, in 1965, demonstrated the formation of bone by a process that he called autoinduction.
N, Ueno, M, Moos
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The concept that there is a substance in bone that can induce new-bone formation has been discussed for many years. However, the credit for the discovery of bone morphogenetic protein goes to Marshall R. Urist, who, in 1965, demonstrated the formation of bone by a process that he called autoinduction.
N, Ueno, M, Moos
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Biochemical and Biophysical Research Communications, 2007
Bone morphogenetic proteins (BMPs) are multi-functional growth factors belonging to the transforming growth factor-beta superfamily. It has been demonstrated that BMPs had been involved in the regulation of cell proliferation, survival, differentiation and apoptosis.
Yong-Tao, Xiao +2 more
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Bone morphogenetic proteins (BMPs) are multi-functional growth factors belonging to the transforming growth factor-beta superfamily. It has been demonstrated that BMPs had been involved in the regulation of cell proliferation, survival, differentiation and apoptosis.
Yong-Tao, Xiao +2 more
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Journal of neurosurgery. Spine, 2009
Although the authors used the same interbody spacers and even higher dose of rhBMP-2 (than the dose of rhBMP-2 was used in another report in which incidence of the resorptions after interbody fusions assisted with rhBMP-2 was 100%) there was no resorptions in their study. We asked for the authors' clarification of the strange phenomenon.
Smoljanović, Tomislav +2 more
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Although the authors used the same interbody spacers and even higher dose of rhBMP-2 (than the dose of rhBMP-2 was used in another report in which incidence of the resorptions after interbody fusions assisted with rhBMP-2 was 100%) there was no resorptions in their study. We asked for the authors' clarification of the strange phenomenon.
Smoljanović, Tomislav +2 more
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Neuroscience, 2000 Bone morphogenetic proteins belong to the transforming growth factor-beta superfamily and act through serine/threonine kinase type I and type II receptors such as bone morphogenetic protein receptor type I and type II.
Elisabeth Traiffort +2 more
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Journal of Dental Research, 1971
Bone morphogenetic protein (BMP) made by the process comprising the steps of demineralizing bone tissue; treating the demineralized bone tissue under aqueous conditions with a water soluble neutral salt and a solubilizing agent for the BMP, the agent being selected from the group consisting of urea and guanidine, and thereby transforming the bone ...
M R, Urist, B S, Strates
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Bone morphogenetic protein (BMP) made by the process comprising the steps of demineralizing bone tissue; treating the demineralized bone tissue under aqueous conditions with a water soluble neutral salt and a solubilizing agent for the BMP, the agent being selected from the group consisting of urea and guanidine, and thereby transforming the bone ...
M R, Urist, B S, Strates
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Bone Morphogenetic Protein and Fusion
Journal of Neurosurgery: Spine, 2007In their article (Villavicencio AT, Burneikiene S, Nelson EL, et al: Safety of transforaminal lumbar interbody fusion and intervertebral recombinant human bone morphogenetic protein– 2. J Neurosurg Spine 3: 436– 443, December, 2005), Villavicencio and colleagues referred to the work by Haid et al., claiming that the fusion rates during ...
Pećina, Marko +2 more
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Progress in Growth Factor Research, 1989
Bone Morphogenetic Protein (BMP) refers to an activity derived from bone that induces the formation of cartilage and bone in vivo. This activity leads to a series of developmental processes including chemotaxis, proliferation, and differentiation, which result in the transient formation of cartilage and the production of living bone tissue, complete ...
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Bone Morphogenetic Protein (BMP) refers to an activity derived from bone that induces the formation of cartilage and bone in vivo. This activity leads to a series of developmental processes including chemotaxis, proliferation, and differentiation, which result in the transient formation of cartilage and the production of living bone tissue, complete ...
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The Bone Morphogenetic Proteins and Their Antagonists
2015The bone morphogenetic proteins (BMPs) and the growth and differentiation factors comprise a single family of some 20 homologous, dimeric cytokines which share the cystine-knot domain typical of the TGF-β superfamily. They control the differentiation and activity of a range of cell types, including many outside bone and cartilage.
Barbara, Mulloy, Chris C, Rider
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Bone morphogenetic protein: a review
International Orthopaedics, 1991The osteogenic potential of bone and bone matrix has been characterised only by its biological effects and the parameters influencing it. Recently, the osteoinductive ability of bone matrix had been defined chemically by the description of a bone morphogenetic protein (BMP), and the parameters of osteogenic factors from different species have now been ...
G, Aldinger +5 more
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