Results 151 to 160 of about 31,100 (249)

Reactions of some 1,1,2-trihalocycloalkanes with morpholine

, 2003
The five to eight membered 1,1,2-trihalocycloalkanes 1 to 5 react with greater than seven equivalents of morpholine under reflux conditions to yield single clean elimination-substitution products: the 2-halo-3-morpholinyl-1-cycloalkenes 7 ...
Prasad, S.H., Nagendrappa, G.
core  

Perspectives for pharmaceutical screening at XFEL sources using the example of Lassa virus endonuclease

Acta Crystallographica Section D, Volume 82, Issue 10, Page 1181-1194, October 2026.
To facilitate structure‐based drug development, XFEL sources are of paramount interest. Here, we analyse the feasibility and data quality of serial femtosecond X‐ray crystallography compound screening at Linac Coherent Light Source and compare it with PETRA III synchrotron experiments.
Sven Falke, Patrick Y. A. Reinke, Daniel Rosenberg, Pontus Fischer, Jan Meyer, Marina Galchenkova, Alexandra Tolstikova, Valerio Mariani, Johanna M. Senst, Philipp Lewe, Susanne Witt, Armin Wagner, Henry N. Chapman, Mark Hunter, Sebastian Günther, Alke Meents   +15 more
wiley   +1 more source

Antifungal Dispensing in Denmark: Patterns Across Primary Care, Secondary Care, and Over‐the‐Counter Sectors

APMIS, Volume 134, Issue 10, October 2026.
ABSTRACT Fungal infections pose a significant health burden in Denmark. Increasing global antifungal use and emerging antifungal resistance underscore the need for ongoing characterization of national prescribing trends to inform antifungal stewardship.
Aditya K. Gupta, Elizabeth M. Teasell, Gregory Pellegrino, Vasiliki Economopoulos, Ditte M. L. Saunte   +4 more
wiley   +1 more source

DNAzymes and Oligodeoxyribonucleotides Immobilized on Aminopropylsilanol and Polylysine‐Anatase Nanoparticles as Active Agents Against Influenza A/H5N1 Virus

Chemical Biology &Drug Design, Volume 108, Issue 4, October 2026.
Scheme of localization of DNAzymes (Dz) and oligonucleotides (ON) on segment 5 of the influenza A/H5N1 virus (A). The nanocomposites based on aminopropylsilanol (Si) and anatase (Ans) nanoparticles bearing Dz and ON effectively inhibit the virus replication in the infected MDCK cells by 2.5–3.5 lg (B).
Marina Repkova, Asya Levina, Ekaterina Filippova, Elena Makarevich, Maria Protsenko, Larisa Shishkina, Artemiy Sergeev, Valentina Zarytova   +7 more
wiley   +1 more source

Synthesis and cellular uptake of neutral rhenium(i) morpholine complexes

Morpholine motifs have been used extensively as targeting moieties for lysosomes, primarily in fluorescence imaging agents. Traditionally these imaging agents are based on organic molecules which have several shortcomings including small Stokes shifts ...
Hackett, M., Hickey, S.M., Hackett, M, Sobolev, A.N., Stagni, S., Bader, C.A., Simpson, P.V., Massi, M., Dallerba, E, Brooks, D.A., Stagni, S, Johnson, IRD, Sorvina, A., Plush, S.E., Plush, SE, Dallerba, E., Hickey, SM, Sobolev, AN, Simpson, PV, Brooks, DA, Sorvina, A, Johnson, I.R.D., Massi, M, Bader, CA   +23 more
core   +1 more source

Stereoselective Synthesis of Morpholine Derivatives by Aziridine-Epoxide Heterocoupling

Morpholine derivatives have properties that are desirable in medicinal chemistry, and this motif has been applied in anti-cancer, anti-inflammatory, anti-viral, and anti-hyperlipidemic drugs.
Mitchell, Teegan
core  

Mapping Regioisomer-Dependent Buchwald-Hartwig C-N Coupling: Bromoimidazo[1,5-a]pyridines as a Model Electrophile Series. [PDF]

Molecules
Sotnik SO, Stetsenko SV, Pavliei IM, Brusylovets OA, Pokholenko OA, Grabchuk GP, Pashenko OY, Volochnyuk DM, Ryabukhin SV.   +8 more
europepmc   +1 more source

In Silico Evaluation via Virtual Screening, ADMET Profiling and Molecular Dynamics Simulations: Synthesis and Biological Activity Analysis of a Novel Antitumor PI3K Inhibitor. [PDF]

Biology (Basel)
Jia W, Ma Y, Zhang Z.
europepmc   +1 more source

Piperazine and Morpholine Protoporphyrin IX Derivatives Intensify Biomolecules Oxidation and Phototoxicity in Triple-Negative Breast Cancer. [PDF]

ChemMedChem
Franco MDS, Lapierre TJWJD, Mendonça TP, Peixoto LFF, Teixeira RR, Guerra JFDC, Tudini KAGY, Ribeiro DL, Espindola FS, Justino AB, Rezende Júnior CO, Tsubone TM.   +11 more
europepmc   +1 more source

Photoinduced Alkynylation of Alkylboronic Acids and Alkyl-Boronates via Aminyl Radical Transfer (ART) Strategy. [PDF]

Chemistry
Bisoyi A, Murgeshan R, G GK, Tripathy AR, Behera A, Bhaskararao B, Yatham VR.   +6 more
europepmc   +1 more source