Results 131 to 140 of about 45,031 (289)

Regioselective reactions of 3,4-pyridynes enabled by the aryne distortion model. [PDF]

, 2013
The pyridine heterocycle continues to play a vital role in the development of human medicines. More than 100 currently marketed drugs contain this privileged unit, which remains highly sought after synthetically. We report an efficient means to access di-
Garg, Neil K, Goetz, Adam E
core  

Fish behavior and its use in the capture and culture of fishes [PDF]

Fishery management, Behaviour, Food fish, Fish culture ...
Bardach, J.E., Magnuson, J.J., May, R.C., Reinhart, J.M. (eds.)   +3 more
core  

Crystal structure of (morpholine-1-carbodithioato-κ²-S,S′)bis(triphenylphosphine-κ-P)gold(I), C₄₁H₃₈AuNOP₂S₂ [PDF]

, 2021
Tunde L. Yusuf, Michael N. Pillay, Sizwe J. Zamisa, Werner E. van Zyl   +3 more
openalex   +1 more source

Synthesis of new derivatives of 4-(4-methyl-5 H -pyrimido[4,5- b ][1,4]thiazin-2-yl)morpholine and 4-methyl-2-(piperidin-1-yl)-5 H -pyrimido[4,5- b ][1,4]thiazine [PDF]

, 2017
Azam Karimian, Hassan Karimian
openalex   +1 more source

Mechanochemical Difluorocarbene‐Mediated C(sp3)–N Bond Cleavage and In Situ Formylation of Tertiary Amines

Advanced Synthesis &Catalysis, Volume 368, Issue 8, 15 April 2026.
A sustainable mechanochemical method for C(sp3)–N bond cleavage and in situ N‐formylation of tertiary amines is developed using a difluorocarbene precursor. The transformation proceeds under mild ball‐milling conditions, demonstrating a broad substrate scope, excellent functional group tolerance, and efficient conversions of diverse aliphatic and ...
Yijie Hu, Peng Wu, Chandan Chittapriya Sahu, Kari Rissanen, Carsten Bolm   +4 more
wiley   +1 more source

Synthesis of Sulfur Heterocycles by Palladium‐Catalyzed Cyclization

European Journal of Organic Chemistry, Volume 29, Issue 14, 15 April 2026.
In spite of the well‐known palladium thiophilicity, sulfur‐containing acyclic substrates may efficiently undergo several different kinds of palladium‐catalyzed cyclization processes leading to highly important sulfur heterocycles in one synthetic step. Advances in this challenging and stimulating field of research are presented in this review.
Bartolo Gabriele
wiley   +1 more source

Synthesis of Polyhydroxylated Pyrrolidinyl Analogs of Sugar Nucleotides. Experimental and Computational Studies on Their Interactions With GalNAC‐T's

ChemBioChem, Volume 27, Issue 7, 14 April 2026.
A multidisciplinary approach based on organic synthesis supported by quantum mechanical calculations, efficient phosphorylation methods, affinity studies using conventional techniques and saturation transfer difference nuclear magnetic resonance, together with molecular dynamics simulations, has enabled the preparation of nucleotide analogs with ...
Pedro Merino, Veronica Juste, Alejandro Montesa, Sandra Pereira, Sara Orta, Manuel Pedrón, Ana I. Jiménez, Sonsoles Martín‐Santamaría, Ramón Hurtado‐Guerrero, Ignacio Delso, Tomás Tejero   +10 more
wiley   +1 more source

2‐Phenylquinolines Exhibit Anti‐Severe Acute Respiratory Syndrome Coronavirus‐2 Activity Through the Nonstructural Protein 13 Helicase Inhibition

ChemMedChem, Volume 21, Issue 7, 14 April 2026.
A SAR study led to the identification of new 2‐phenylquinoline‐based derivatives that exhibit anti‐Severe Acute Respiratory Syndrome Coronavirus‐2 (SARS‐CoV‐2) activity by acting as ATP‐competitive inhibitors of nonstructural protein 13 (nsp13) helicase.
Giada Cernicchi, Maria Giulia Nizi, Roberta Emmolo, Leentje Persoons, Manon Laporte, Dirk Jochmans, Isabella Romeo, Giacomo Pepe, Ciro Milite, Pietro Campiglia, Jacopo Spezzini, Alma Martelli, Simone Brogi, Francesca Esposito, Tommaso Felicetti, Serena Massari, Giuseppe Manfroni, Stefano Sabatini, Gianluca Sbardella, Stefano Alcaro, Johan Neyts, Angela Corona, Enzo Tramontano, Steven De Jonghe, Oriana Tabarrini   +24 more
wiley   +1 more source

Quaternized Curcumin Derivative—Synthesis, Physicochemical Characteristics, and Photocytotoxicity, Including Antibacterial Activity after Irradiation with Blue Light

Molecules
Over the past few years, numerous bacterial strains have become resistant to selected drugs from various therapeutic groups. A potential tool in the fight against these strains is antimicrobial photodynamic therapy (APDT).
Pawel Bakun, Marcin Wysocki, Magdalena Stachowiak, Marika Musielak, Jolanta Dlugaszewska, Dariusz T. Mlynarczyk, Lukasz Sobotta, Wiktoria M. Suchorska, Tomasz Goslinski   +8 more
doaj   +1 more source

Formylation with "Supercritical” CO2: Efficient Ruthenium-Catalyzed Synthesis of N -Formylmorpholine [PDF]

, 2018
Formylation of morpholine with "supercritical” CO2 using the bidentate ruthenium catalyst RuCl2(dppe)2 affords high N-formylmorpholine production rate at almost 100% selectivity. The solventless reaction could be an interesting alternative to the present
Baiker, Alfons, Engel, Dominique, Schmid, Leo, Schneider, Michael   +3 more
core