Results 111 to 120 of about 24,393 (218)
Morpholine as a privileged scaffold for neurodegenerative disease therapeutics. [PDF]
Parmbil SK +7 more
europepmc +1 more source
TANK‐binding kinase 1 (TBK1) is a key regulator of innate immune signalling and an emerging therapeutic target. Here, we report the design, synthesis, and biological evaluation of isoflavonoid TBK1‐modulating analogues, achieving a sixfold enhancement in inhibition of TBK1 signalling relative to the clinically relevant idronoxil (IDX) parent scaffold ...
Valerio Falasca +5 more
wiley +1 more source
4-[4-(4-Chloro-1,2,5-thia-diazol-3-yl)phen-yl]morpholine. [PDF]
Palme PR +4 more
europepmc +1 more source
A modular continuous‐flow platform enables the Pd‐catalyzed carbonylative N‐aroylation of sulfoximines using carbon monoxide (CO) generated on demand from carbon dioxide (CO2) via solid oxide electrolysis cell (SOEC). The integration of a heterogeneous palladium catalyst and a biomass‐derived solvent provides a safe, scalable, and sustainable route to ...
Giada Moroni +8 more
wiley +1 more source
Cyrene Dimethyl Acetal: Potential Alternative Solvent for Pd-Catalyzed Homogeneous Aminocarbonylation of Iodo(hetero)arene Compounds. [PDF]
Takács A +6 more
europepmc +1 more source
Nucleophilic substitution of a phthalimidyl group with morpholine in an N<sup>1</sup>-methyl-1,2,3-triazole: crystallographic evidence for migration of the methylene bridge. [PDF]
Palme PR +5 more
europepmc +1 more source
Molecular Editing of Bilobalide: Regioselective C-Ring Lactam Formation. [PDF]
Wang W +5 more
europepmc +1 more source
Near‐infrared fluorescent pH indicators based on perylenediimide were constructed in a modular receptor–spacer–fluorophore–spacer–receptor format with heterocyclic amino moieties at the bay positions. Counterintuitively, the dibrominated intermediate with two heavy atoms is more emissive than the heterocyclic compounds.
Luke Camenzuli +4 more
wiley +1 more source

