Results 91 to 100 of about 27,629 (258)

Development of an Efficient and Scalable Process for Preparing Timolol N‐Nitrosamine Impurities B, C, E, H, I, J, and Their ADMET Evaluation

Journal of Heterocyclic Chemistry, EarlyView.
N‐nitrosamine impurities (B, C, E, H, I, J) of timolol maleate are easily synthesized from diethyl malonate and 3,4‐dichloro‐1,2,5‐thiadiazole. Good yields and precise impurity profiling are made possible by the effective technique, which also ensures pharmaceutical safety and strengthens regulatory compliance.
Kottolla Sai Prasad, Chithaluri Sudhakar, Vijaya Krishna Ravi, Bijaya Kethan Sahoo   +3 more
wiley   +1 more source

Bio‐Inspired, Zwitterionic Copolymers with Amphiphilic Character

Macromolecular Rapid Communications, EarlyView.
Zwitterionic copolymers based on arginine‐derived monomers are produced by xanthate‐supported photo‐iniferter reversible‐addition‐fragmentation chain‐transfer polymerization. Experiments in relevant conditions show that the designed (co)polymers hardly interact with biologically relevant proteins and enzymes such as bovine serum albumine (BSA), fetal ...
Theresa M. Lutz, Cevin P. Braksch, Jonas De Breuck, Matthias Hartlieb, Meike N. Leiske   +4 more
wiley   +1 more source

Morpholines, V

Zeitschrift für Naturforschung B, 1972
A new synthesis has been developed for the hitherto unreported 2-substituted-3-oxo-4H-1,4-oxazines 3b-3j via the cyclodehydrohalogenation of N-aryl-N-dichloroacetyl-2-amino-4′-nitroacetophenones in dimethyl sulfoxide with potassium t-butoxide. The structures of all the oxazine derivatives have been verified by IR and NMR spectroscopy and correlations ...
openaire   +1 more source

Chain‐End Grafting of RAFT Polyelectrolyte Macroligands to Stabilize Near‐Infrared‐Emitting Gold Nanoclusters

Macromolecular Rapid Communications, EarlyView.
Surface‐functionalized gold nanoclusters (AuNCs) are synthesized in situ by chain‐end grafting of RAFT polyelectrolytes at room temperature directly in water. It leads to highly stable polymer‐AuNCs nanohybrids emitting near‐infrared photoluminescence with µs lifetimes. ABSTRACT With their photoluminescence properties, gold nanoclusters (AuNCs, d<2 nm)
Bárbara Casteleiro, Pierre Alcouffe, Fernande Da Cruz, Agnès Crépet, José Manuel Gaspar Martinho, Marie‐Thérèse Charreyre, José Paulo Sequeira Farinha, Arnaud Favier   +7 more
wiley   +1 more source

Synthesis of new derivatives of 4-(4-methyl-5 H -pyrimido[4,5- b ][1,4]thiazin-2-yl)morpholine and 4-methyl-2-(piperidin-1-yl)-5 H -pyrimido[4,5- b ][1,4]thiazine [PDF]

, 2017
Azam Karimian, Hassan Karimian
openalex   +1 more source

Unveiling contrasting iron efficiency strategies in common bean (Phaseolus vulgaris L.) genotypes under iron deficiency

Plant Biology, EarlyView.
Common bean genotypes differ in their iron acquisition through distinct Strategy I responses and root exudation patterns. Abstract Iron (Fe) deficiency in food crops, particularly on calcareous soils, limits productivity and human nutrition. This study investigated two common bean (Phaseolus vulgaris) genotypes, Guaymí (high Fe‐accumulating, HI) and ...
F. X. Rucamumihigo, U. Ludewig, A. Hernández‐Pridybailo, I. Cakmak, N. J. Maywald   +4 more
wiley   +1 more source

Exploration of morpholine-thiophene hybrid thiosemicarbazones for the treatment of ureolytic bacterial infections via targeting urease enzyme: Synthesis, biochemical screening and computational analysis

Frontiers in Chemistry
An important component of the pathogenicity of potentially pathogenic bacteria in humans is the urease enzyme. In order to avoid the detrimental impact of ureolytic bacterial infections, the inhibition of urease enzyme appears to be an appealing approach.
Rubina Munir, Sumera Zaib, Muhammad Zia-ur-Rehman, Hira Javed, Ayesha Roohi, Muhammad Zaheer, Nabiha Fatima, Mashooq Ahmad Bhat, Imtiaz Khan   +8 more
doaj   +1 more source

Microsolvation of morpholine, a bidentate base – the importance of cooperativity [PDF]

, 2012
Margarita M. Vallejos, Al Mokhtar Lamsabhi, Nélida M. Peruchena, Otília Mó, Manuel Yáñez   +4 more
openalex   +1 more source

Synthesis, Electrochemistry, In Vitro Antiprotozoal Efficacy and Mechanistic Study of Novel ‘Ferrantoin’ and Related Derivatives

Applied Organometallic Chemistry, Volume 40, Issue 7, July 2026.
1,2‐Disubstituted ferrocene analogues bearing hydantoin or rhodanine synthons were synthesised and assessed for antitrypanosomatid activity. An antileishmanial early lead, analogue 23, acting through ROS generation and hence oxidative stress, was uncovered.
Maryna Saayman, Janine Aucamp, Helena D. Janse van Rensburg, Christina Kannigadu, Rotondwa Mphephu, Andrew J. Swarts, Keisuke Suganuma, David D. N'Da   +7 more
wiley   +1 more source

Synthesis and properties of morpholino-substituted 2H-imidazole N-oxides as potential endothelioprotectors

Chimica Techno Acta
5-Morpholino-substituted 2H-imidazole 1-oxides have recently proven themselves as perspective molecules to counteract the pathological states associated with endothelial dysfunction.
Alexey A. Akulov, Anna A. Nelyubina, Ilya I. Butorin, Vsevolod V. Melekhin, Maria D. Tokhtueva, Mikhail V. Korokin, Mikhail V. Pokrovskii, Mikhail V. Varaksin, Oleg N. Chupakhin   +8 more
doaj   +1 more source