Results 81 to 90 of about 29,476 (244)
Allosteric Inhibitors of SARS‐CoV‐2 RNA‐Dependent RNA Polymerase Based on N,N′‐Diphenylurea
ChemMedChem, Volume 21, Issue 1, January 2026.Inhibitors of SARS‐CoV‐2 RdRp activity based on N,N′‐diphenylurea scaffold have been identified. Several compounds exhibit residual activity (RA) below 50% in an enzymatic assay (at 10 µM concentration) and improved aqueous solubility compared to the previously reported series of inhibitors.
Artem Chayka +11 more
wiley +1 more source
ChemMedChem, Volume 21, Issue 1, January 2026.Investigation of the structure‐activity relationship on W482 (1) with a pyrimidine‐2,4‐diamine scaffold culminated in analog 51 with enhanced anti‐plasmodial activity. Forward genetics and phenotypic examination revealed the ABCI3 transporter protein as a putative resistance mechanism.
Mahta Mansouri +14 more
wiley +1 more source
Synthesis, Antitumor Evaluation and Molecular Docking of New Morpholine Based Heterocycles [PDF]
, 2017 Zeinab A. Muhammad +5 more
openalex +1 more source
ChemSusChem, Volume 19, Issue 1, January 2026.Sustainable one‐pot synthesis of functionalized γ‐hydroxy derivatives in deep eutectic solvents. A green, sequential CC/CX bond‐forming strategy enables diverse γ‐hydroxy derivatives via Morita–Baylis–Hillman and nucleophilic functionalization in ChCl/Gly deep eutectic solvent.
Marina Ramos‐Martín +3 more
wiley +1 more source
Anti‐Tubercular Drug‐Induced Liver Injury: Current Understanding and Emerging Directions
JGH Open, Volume 10, Issue 1, January 2026.ABSTRACT Most common adverse effect causing cessation of anti‐tubercular treatment (ATT) is drug‐induced liver injury (DILI) which is unpredictable due to its idiosyncratic nature. ATT is the most common cause of DILI and drug‐induced acute liver failure (ALF) in South East Asia.
Shubham Prasad +3 more
wiley +1 more source
Macromolecular Materials and Engineering, Volume 311, Issue 1, January 2026.Microcrystalline cellulose was surface modified using itaconic anhydride and used as a reinforcing particle in biobased itaconated castor oil and isobornyl (meth)acrylate formulations for vat photopolymerisation additive manufacturing. The polymers displayed tailorable and competitive mechanical properties, low polymerisation shrinkage, detailed ...
James A. Dicks, Chris Woolard
wiley +1 more source
Retraction Note: A Zinc Morpholine Complex Prevents HCl/Ethanol-Induced Gastric Ulcers in a Rat Model [PDF]
Suzy Munir Salama +6 more
openalex +1 more source
Synthesis of Novel Methacrylate Monomers and Their Application in MSLA‐Printed Microneedles
ChemistrySelect, Volume 11, Issue 2, 15 January 2026.Biocompatible acrylate‐based resins enable the MSLA 3D printing of multifunctional microneedles with tunable properties and effective skin penetration. ABSTRACT This study aims to develop biocompatible resins to fabricate microneedles (MNs) using mask stereolithography (MSLA) as a 3D printing technology.
Rubson P. S. Ribeiro +4 more
wiley +1 more source