Heavy ion mutagenesis combined with triclosan screening provides a new strategy for improving the arachidonic acid yield in Mortierella alpina [PDF]
BMC Biotechnology, 2018 Background Arachidonic acid (ARA), which is a ω-6 polyunsaturated fatty acid, has a wide range of biological activities and is an essential component of cellular membranes in some human tissues.
Huidan Zhang +5 more
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Genome characterization of the oleaginous fungus Mortierella alpina. [PDF]
PLoS ONE, 2011 Mortierella alpina is an oleaginous fungus which can produce lipids accounting for up to 50% of its dry weight in the form of triacylglycerols. It is used commercially for the production of arachidonic acid.
Lei Wang +25 more
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Tetrahydrobiopterin Plays a Functionally Significant Role in Lipogenesis in the Oleaginous Fungus Mortierella alpina [PDF]
Frontiers in Microbiology, 2020 Tetrahydrobiopterin (BH4) is well-known as a cofactor of phenylalanine hydroxylase (PAH) and nitric oxide synthase (NOS), but its exact role in lipogenesis is unclear.
Hongchao Wang +18 more
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Application of a ω-3 Desaturase with an Arachidonic Acid Preference to Eicosapentaenoic Acid Production in Mortierella alpina [PDF]
Frontiers in Bioengineering and Biotechnology, 2018 In the industrial oleaginous fungus Mortierella alpina, the arachidonic acid (AA; C20:4; ω-6) fraction can reach 50% of the total fatty acids (TFAs) in vivo.
Chengfeng Ge +21 more
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Production of Arachidonic Acid and Eicosapentaenoic Acid by Mortierella alpina CBS 528.72 on Date Waste [PDF]
Food Technology and Biotechnology, 2018 Arachidonic acid (ARA) and eicosapentaenoic acid (EPA) are important for human health and are produced by the fungus Mortierella alpina. Fermentation conditions may affect fatty acid profile of produced oil.
Seyedeh Zeinab Asadi +3 more
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Macro-morphological characterization and kinetics of Mortierella alpina colonies during batch cultivation. [PDF]
PLoS ONE, 2018 An effective method for research of macro-morphological characterization and its kinetics was developed by studying the macro-morphological characteristics of Mortierella alpina, an oleaginous zygomycete widely used to produce lipids rich in PUFA, in ...
Xue Fang +7 more
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Ice nucleation activity in the widespread soil fungus Mortierella alpina [PDF]
Biogeosciences, 2015 Biological residues in soil dust are a potentially strong source of atmospheric ice nuclei (IN). So far, however, the abundance, diversity, sources, seasonality, and role of biological – in particular, fungal – IN in soil dust have not been characterized.
J. Fröhlich-Nowoisky +5 more
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The Role of Glyceraldehyde-3-Phosphate Dehydrogenases in NADPH Supply in the Oleaginous Filamentous Fungus Mortierella alpina [PDF]
Frontiers in Microbiology, 2020 Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is a highly conserved enzyme within the glycolytic pathway. GAPDH catalyzes the transformation of glyceraldehyde 3-phosphate to glycerate-1, 3-biphosphate, a process accompanied by the production of NADH ...
Shunxian Wang +20 more
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An Online Respiratory Quotient-Feedback Strategy of Feeding Yeast Extract for Efficient Arachidonic Acid Production by Mortierella alpina [PDF]
Frontiers in Bioengineering and Biotechnology, 2018 Mortierella alpina (M. alpina) is well known for arachidonic acid (ARA) production. However, low efficiency and unstableness are long existed problems for industrial production of ARA by M. alpina due to the lack of online regulations.
Xiangyu Li +14 more
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Production of Arachidonic Acid by Mortierella alpina I49-N18 [PDF]
Food Technology and Biotechnology, 2002 Arachidonic acid (AA), an essential fatty acid in human body, fermented by Mortierella alpina I49-N18 was investigated in a shake-flask, and a 50-ton fermentor.
Ji Wang +5 more
doaj +3 more sources