Regulation of the Leucine Metabolism in Mortierella alpina [PDF]
Journal of Fungi, 2022 The oleaginous fungus Mortierella alpina is a safe source of polyunsaturated fatty acids (PUFA) in industrial food and feed production. Besides PUFA production, pharmaceutically relevant surface-active and antimicrobial oligopeptides were isolated from ...
Robin Sonnabend +2 more
doaj +6 more sources
Expression of Vitreoscilla hemoglobin enhances production of arachidonic acid and lipids in Mortierella alpina [PDF]
BMC Biotechnology, 2017 Background Arachidonic acid (ARA, C20:4, n-6), which belongs to the omega-6 series of polyunsaturated fatty acids and has a variety of biological activities, is commercially produced in Mortierella alpina.
Huidan Zhang +3 more
doaj +4 more sources
Arachidonic acid production by the oleaginous fungus Mortierella alpina 1S-4: A review [PDF]
Journal of Advanced Research, 2018 The filamentous fungus Mortierella alpina 1S-4 is capable of accumulating a large amount of triacylglycerol containing C20 polyunsaturated fatty acids (PUFAs). Indeed, triacylglycerol production by M.
Hiroshi Kikukawa +4 more
doaj +6 more sources
Heavy ion mutagenesis combined with triclosan screening provides a new strategy for improving the arachidonic acid yield in Mortierella alpina [PDF]
BMC Biotechnology, 2018 Background Arachidonic acid (ARA), which is a ω-6 polyunsaturated fatty acid, has a wide range of biological activities and is an essential component of cellular membranes in some human tissues.
Huidan Zhang +5 more
doaj +3 more sources
Investigation on Cell Disruption Techniques and Supercritical Carbon Dioxide Extraction of Mortierella alpina Lipid [PDF]
Foods, 2022 Mortierella alpina, an oleaginous fungus, has been shown to be a potential source for arachidonic acid (ARA) production. The recovery of intracellular lipids from M.
Chang Chng Ong, Yen-Hui Chen
doaj +3 more sources
Production of Arachidonic Acid and Eicosapentaenoic Acid by Mortierella alpina CBS 528.72 on Date Waste [PDF]
Food Technology and Biotechnology, 2018 Arachidonic acid (ARA) and eicosapentaenoic acid (EPA) are important for human health and are produced by the fungus Mortierella alpina. Fermentation conditions may affect fatty acid profile of produced oil.
Seyedeh Zeinab Asadi +3 more
doaj +3 more sources
Macrophage-targeting oligopeptides from Mortierella alpina. [PDF]
Chem Sci, 2022 Specificity profiling of a nonribosomal peptide synthetase of an early diverging fungus revealed high substrate flexibility. Feeding studies with click-functionalised amino acids enabled the production of fluorescent peptides targeting macrophages.
Wurlitzer JM +7 more
europepmc +3 more sources
Insecticidal Cyclodepsitetrapeptides from Mortierella alpina
Journal of Natural Products, 2023 Early diverging fungi, such as Mortierella alpina, are an emerging source of bioactive peptides. By screening 22 fungal isolates together with precursor-directed biosynthesis, a family of threonine-linked cyclotetradepsipeptides, the cycloacetamides A–F (
Johannes Rassbach (16411595) +13 more
core +3 more sources
Characterization of NAD+/NADP+-Specific Isocitrate Dehydrogenases From Oleaginous Fungus Mortierella alpina Involved in Lipid Accumulation [PDF]
Frontiers in Nutrition, 2021 Mortierella alpina has a strong capacity for lipid accumulation. Isocitrate dehydrogenase (IDH) plays an important role in affecting the flow of intracellular carbon sources and reducing power NADPH for lipid biosynthesis.
Xin Tang +21 more
doaj +2 more sources
Autophagy Improves ARA-Rich TAG Accumulation in Mortierella alpina by Regulating Resource Allocation [PDF]
Microbiology Spectrum, 2022 The present study was designed to explore the possibility of improving lipid production in oleaginous filamentous fungus Mortierella alpina based on an autophagy regulation strategy.
Hengqian Lu +6 more
doaj +2 more sources