Results 101 to 110 of about 1,451,444 (296)
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Sanat ve İkonografi DergisiTürklerin yerleşik hayata geçmesi ile birlikte barınma yerlerini inşasında ilk olarak toprak kullanmışlar ve daha sonra Selçuklular dönemi ile tuğla ve taş kullanmaya başlamışlardır.
Ahmet Melih Çilingir +1 more
doaj +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
„Kõik on muidugi selle poolt.” Koosoleku motiiv sotsialistliku korra retrospektiivsel kujutamisel
Keel ja Kirjandus”Everybody’s in favour, of course.” Meetings as a motif in retrospective depictions of the socialist order This article examines the portrayal of meetings in four novels: Enn Vetemaa’s “The Musician” (Pillimees), Herta Müller’s “The Land of Green ...
Inga Kirs
doaj +1 more source
“Pemanfaatan Tepung Sukun Pada Pembuatan Cake Sebagai Upaya Untuk Meningkatkan Citra Pangan Lokal” [PDF]
, 2012 Tujuan dari penelitian ini adalah untuk : 1) Menemukan resep yang tepat untuk menghasilkan white forest pie, mini chocolate cake dan roll cake motif berbahan tepung sukun sehingga menghasilkan produk yang disukai oleh masyarakat.2) Menemukan teknik ...
OKKY SUSILO , UTAMI
core
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
, 2014 Next-generation sequencing technology enables the identification of thousands of gene regulatory sequences in many cell types and organisms. We consider the problem of testing if two such sequences differ in their number of binding site motifs for a ...
Friedrich, Tara +3 more
core +1 more source
Information SciencesLattices are a commonly used structure for the representation and analysis of relational and ontological knowledge. In particular, the analysis of these requires a decomposition of a large and high-dimensional lattice into a set of understandably large parts. With the present work we propose /ordinal motifs/ as analytical units of meaning.
Johannes Hirth +3 more
openaire +2 more sources
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source