Results 91 to 100 of about 652,018 (265)
Molecular Oncology, EarlyView.This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu +3 more
wiley +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
Kahramanmaras Çeyiz Sandığı Oyma Motiflerinin Đncelenmesi
Düzce University Faculty of Forestry Journal of Forestry, 2008 Bu çalısmayla gün geçtikçe kaybolan oymacılığın ve çeyiz sandığı oymamotiflerinin muhafaza edilerek, gelecek nesillere aktarılması amaçlanmıstır. Çeyizsandığı oymacılığı Türkiye’de en yaygın olarak Kahramanmaras ilinde yapılmaktadır.Bu arastırmada ...
Murat Özalp, Derya Sevim Korkut
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PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
KONYA MERAM İLÇESİKARADİĞİN KASABASI’NDA KANAVİÇE İŞLEMELER
Selçuk Üniversitesi Sosyal Bilimler Enstitüsü Dergisi, 2004 Anadolu’nun çeşitli yörelerinde tekniği aynı, fakat, motif, renk ve kompozisyon farklılıklarıile karşımıza çıkan kanaviçe işlemelerine; Konya Meram İlçesi Karadiğin Kasabası’nda rastlanmıştır.
Gülizar Altun
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Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Novel High Content Multi-Parametric Cell-Based Assays
BioTechniques, 2007 Chris Shumate +3 more
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Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Identifying vital nodes algorithm in social networks fusing higher-order information
Tongxin xuebao, 2019 Identifying vital nodes is a basic problem in complex network research.The existing theoretical framework,mainly considered from the lower-order structure of node-based and edge-based relations often ignores important factors such as interactivity and ...
Guanghui YAN +4 more
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