Results 11 to 20 of about 769,499 (354)

Motile ciliopathies

open access: yesNature Reviews Disease Primers, 2020
Motile cilia are highly complex hair-like organelles of epithelial cells lining the surface of various organ systems. Genetic mutations (usually with autosomal recessive inheritance) that impair ciliary beating cause a variety of motile ciliopathies, a heterogeneous group of rare disorders. The pathogenetic mechanisms, clinical symptoms and severity of
Wallmeier, Julia   +6 more
openaire   +6 more sources

A Systematic and a Scoping Review on the Psychometrics and Clinical Utility of the Volume-Viscosity Swallow Test (V-VST) in the Clinical Screening and Assessment of Oropharyngeal Dysphagia

open access: yesFoods, 2021
(1) Background: The volume-viscosity swallow test (V-VST) is a clinical tool for screening and diagnosis of oropharyngeal dysphagia (OD). Our aims were to examine the clinical utility of the V-VST against videofluoroscopy (VFS) or fiberoptic endoscopic ...
Stephanie A. Riera   +7 more
doaj   +1 more source

Objective assessment of eye alignment and disparity-driven vergence in Parkinson’s disease

open access: yesFrontiers in Aging Neuroscience, 2023
BackgroundSelf-reported diplopia is described in up to one-third of Parkinson’s disease (PD) patients.ObjectiveThe purpose of our study was to expand our understanding of the mechanistic underpinnings of diplopia in PD. We hypothesize that the time-based
Palak Gupta   +12 more
doaj   +1 more source

Effects of in vitro lipid overload on LX-2 hepatic stellate cells

open access: yesAnnals of Hepatology, 2022
Introduction and Objectives: Studying lipid overload repercussions on hepatic stellate cells (HSC) is of great importance due to their role in fibrosis during NAFLD. Steatogenic cell culture of HSC is intended to elucidate pathogenic mechanisms in NAFLD.
A Campos-Espinosa   +2 more
doaj   +1 more source

Motility Assay: Twitching Motility [PDF]

open access: yes, 2014
Twitching motility is a mode of solid surface translocation that occurs under humid conditions on semisolid or solid surfaces, is dependent on the presence of retractile type IV pili and is independent of the presence of a flagellum. Surface translocation via twitching motility is powered by the extension and retraction of type IV pili and can manifest
Lynne, Turnbull, Cynthia B, Whitchurch
openaire   +2 more sources

Loss of Unconventional Myosin VI Affects cAMP/PKA Signaling in Hindlimb Skeletal Muscle in an Age-Dependent Manner

open access: yesFrontiers in Physiology, 2022
Myosin VI (MVI) is a unique unconventional myosin ubiquitously expressed in metazoans. Its diverse cellular functions are mediated by interactions with a number of binding partners present in multi-protein complexes.
Lilya Lehka   +5 more
doaj   +1 more source

A new interpretation and quantitative method for diplopia test: 304 cases of ocular motor nerve palsy for clinical test and verify [PDF]

open access: yesInternational Journal of Ophthalmology, 2017
We introduce a new interpretation and quantitative method for computerized diplopia test. By comparing this new method to the Hess screen test, we validate its applicability among 304 patients with ocular motor nerve palsy.
Ling-Yun Zhou   +5 more
doaj   +1 more source

Assessment of cellular proliferation, death and senescence in a model of steatosis in vitro

open access: yesAnnals of Hepatology, 2022
Introduction and objectives: Hepatocyte cell culture in steatogenic medium is a useful, reproducible tool. During NAFLD, cells undergo processes in response to the steatogenic input. Here we aimed to study cellular proliferation, death, and senescence in
A Campos-Espinosa   +2 more
doaj   +1 more source

Parasite motility is critical for virulence of African trypanosomes. [PDF]

open access: yes, 2018
African trypanosomes, Trypanosoma brucei spp., are lethal pathogens that cause substantial human suffering and limit economic development in some of the world's most impoverished regions.
Geng, Quanjie   +6 more
core   +1 more source

How myosin VI traps its off-state, is activated and dimerizes

open access: yesNature Communications, 2023
Myosin VI (Myo6) is the only minus-end directed nanomotor on actin, allowing it to uniquely contribute to numerous cellular functions. As for other nanomotors, the proper functioning of Myo6 relies on precise spatiotemporal control of motor activity via ...
Louise Canon   +22 more
doaj   +1 more source

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