Results 11 to 20 of about 731,626 (335)

The Motility of Mollicutes [PDF]

open access: yesBiophysical Journal, 2003
Recent experiments show that the conformation of filament proteins play a role in the motility and morphology of many different types of bacteria. Conformational changes in the protein subunits may produce forces to drive propulsion and cell division. Here we present a molecular mechanism by which these forces can drive cell motion.
Oleg A. Igoshin   +2 more
openaire   +3 more sources

Motile ciliopathies

open access: yesNature Reviews Disease Primers, 2020
Motile cilia are highly complex hair-like organelles of epithelial cells lining the surface of various organ systems. Genetic mutations (usually with autosomal recessive inheritance) that impair ciliary beating cause a variety of motile ciliopathies, a heterogeneous group of rare disorders. The pathogenetic mechanisms, clinical symptoms and severity of
Wallmeier, Julia   +6 more
openaire   +6 more sources

Motility Assay: Twitching Motility [PDF]

open access: yes, 2014
Twitching motility is a mode of solid surface translocation that occurs under humid conditions on semisolid or solid surfaces, is dependent on the presence of retractile type IV pili and is independent of the presence of a flagellum. Surface translocation via twitching motility is powered by the extension and retraction of type IV pili and can manifest
Lynne Turnbull, Cynthia B. Whitchurch
openaire   +2 more sources

Cell Motility and Cancer [PDF]

open access: yesCancers, 2020
Cell migration is an essential systemic behavior, tightly regulated, of all living cells endowed with directional motility that is involved in the major developmental stages of all complex organisms such as morphogenesis, embryogenesis, organogenesis, adult tissue remodeling, wound healing, immunological cell activities, angiogenesis, tissue repair ...
Ildefonso M. De la Fuente   +2 more
openaire   +4 more sources

Formation of Aberrant Myotubes by Myoblasts Lacking Myosin VI Is Associated with Alterations in the Cytoskeleton Organization, Myoblast Adhesion and Fusion

open access: yesCells, 2020
We have previously postulated that unconventional myosin VI (MVI) could be involved in myoblast differentiation. Here, we addressed the mechanism(s) of its involvement using primary myoblast culture derived from the hindlimb muscles of Snell’s waltzer ...
Lilya Lehka   +6 more
doaj   +1 more source

Mechanistic and structural basis for activation of cardiac myosin force production by omecamtiv mecarbil

open access: yesNature Communications, 2017
Omecamtiv mecarbil (OM) is a cardiac myosin activator that is currently in clinical trials for heart failure treatment. Here, the authors give insights into its mode of action and present the crystal structure of OM bound to bovine cardiac myosin, which ...
Vicente J. Planelles-Herrero   +4 more
doaj   +1 more source

Orbital magnetic resonance imaging is useful in age-related distance esotropia

open access: yesJournal of Optometry, 2018
Purpose: To describe findings for orbital magnetic resonance imaging (MRI) in patients with age-related distance esotropia (ARDE). Methods: We compared 31 orbital MRI from patients with ARDE (77 ± 7 SD years) with 2 control groups: 32 orbits from ...
Pilar Gómez de Liaño Sanchez   +3 more
doaj   +1 more source

Myosin 7 and its adaptors link cadherins to actin

open access: yesNature Communications, 2017
Cadherin is essential for mechanotransduction and myosin-adaptor-harmonin complexes anchor it to actin. Here the authors present the structures of myosin 7 MF2 domains bound to the harmonin PDZ3c domain and give insights into myosin-adaptor-harmonin ...
I-Mei Yu   +8 more
doaj   +1 more source

Caffeine Inhibits EGF-Stimulated Trophoblast Cell Motility through the Inhibition of mTORC2 and Akt. [PDF]

open access: yes, 2012
Impaired trophoblast invasion is associated with pregnancy disorders such as early pregnancy loss and preeclampsia. There is evidence to suggest that the consumption of caffeine during pregnancy may increase the risk of pregnancy loss; however, little is
Alison E. Wallace   +46 more
core   +1 more source

Extraocular Muscle Imbalance and Outcomes of Scleral Buckling Surgery for Primary Rhegmatogenous Retinal Detachment [PDF]

open access: yes, 2020
Objective: The objective was to study the muscle imbalance, restrictive motility in unlike gazes and the outcomes of the scleral buckling surgery for rhegmatogenous retinal detachment.
Kawish, A. B. (Ayesha)   +2 more
core   +1 more source

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