Results 11 to 20 of about 742,756 (306)

A Unifying Model-Based Hypothesis for the Diverse Waveforms of Infantile Nystagmus Syndrome

Journal of Eye Movement Research, 2011
We expanded the original behavioral Ocular Motor System (OMS) model for Infantile Nystagmus Syndrome (INS) by incorporating common types of jerk waveforms within a unifying mechanism.
Zhong I. Wang, Louis F. Dell'Osso
doaj   +1 more source

Frictional Active Brownian Particles

, 2020
Frictional forces affect the rheology of hard-sphere colloids, at high shear rate. Here we demonstrate, via numerical simulations, that they also affect the dynamics of active Brownian particles, and their motility induced phase separation.
Chattoraj, Joyjit, Ciamarra, Massimo Pica, Doyle, Patrick, Ni, Ran, Nie, Pin, Piscitelli, Antonio   +5 more
core   +1 more source

Relation of Gallbladder Motility to Viscosity and Composition of Gallbladder Bile in Patients with Cholesterol Gallstones [PDF]

, 2009
Background/Aims: Increased viscosity and supersaturation of cholesterol in gallbladder bile, as well as an impaired motility of the gallbladder, are considered to be important factors in the pathogenesis of cholesterol gallstones.
Althaus, Rupert, del Pozo, Reginald, Gruendel, Denis, Huettl, Thomas P., Juengst, Christoph, Juengst, Dieter, Neubrand, Michael, Schneider, Berthold, Spelsberg, Fritz W., Straub, Gundula   +9 more
core   +1 more source

Mechanistic and structural basis for activation of cardiac myosin force production by omecamtiv mecarbil

Nature Communications, 2017
Omecamtiv mecarbil (OM) is a cardiac myosin activator that is currently in clinical trials for heart failure treatment. Here, the authors give insights into its mode of action and present the crystal structure of OM bound to bovine cardiac myosin, which ...
Vicente J. Planelles-Herrero, James J. Hartman, Julien Robert-Paganin, Fady I. Malik, Anne Houdusse   +4 more
doaj   +1 more source

Caffeine Inhibits EGF-Stimulated Trophoblast Cell Motility through the Inhibition of mTORC2 and Akt. [PDF]

, 2012
Impaired trophoblast invasion is associated with pregnancy disorders such as early pregnancy loss and preeclampsia. There is evidence to suggest that the consumption of caffeine during pregnancy may increase the risk of pregnancy loss; however, little is
Alison E. Wallace, Bauer, Beavo, Biadasiewicz, Boulbes, Brent, Brooke Lumicisi, Brosens, Burton, CARE Study Group, Cartwright, Cartwright, Cartwright, Chui, Di Fiore, Fabro, Foukas, Goldstein, Gude, Guy S. Whitley, Hofmann, Isobelle Grant, Jang, Judith E. Cartwright, Julien, LaMarca, LaMarca, LaMarca, Lee, Liu, Marone, Maslova, Mei, Olayioye, Omori, Pollheimer, Robertson, Spindle, Stefanidou, Tsygankova, Wadge, Weng, Yarden, Yarden, Yoshino, Zhang, Zoncu   +46 more
core   +1 more source

Myosin 7 and its adaptors link cadherins to actin

Nature Communications, 2017
Cadherin is essential for mechanotransduction and myosin-adaptor-harmonin complexes anchor it to actin. Here the authors present the structures of myosin 7 MF2 domains bound to the harmonin PDZ3c domain and give insights into myosin-adaptor-harmonin ...
I-Mei Yu, Vicente J. Planelles-Herrero, Yannick Sourigues, Dihia Moussaoui, Helena Sirkia, Carlos Kikuti, David Stroebel, Margaret A. Titus, Anne Houdusse   +8 more
doaj   +1 more source

Orbital magnetic resonance imaging is useful in age-related distance esotropia

Journal of Optometry, 2018
Purpose: To describe findings for orbital magnetic resonance imaging (MRI) in patients with age-related distance esotropia (ARDE). Methods: We compared 31 orbital MRI from patients with ARDE (77 ± 7 SD years) with 2 control groups: 32 orbits from ...
Pilar Gómez de Liaño Sanchez, Gloria Olavarri González, Pilar Merino Sanz, Jose C. Escribano Villafruela   +3 more
doaj   +1 more source

Elucidation of the Photorhabdus temperata Genome and Generation of a Transposon Mutant Library To Identify Motility Mutants Altered in Pathogenesis [PDF]

, 2015
The entomopathogenic nematode Heterorhabditis bacteriophora forms a specific mutualistic association with its bacterial partner Photorhabdus temperata.
Abebe-Akele, Feseha, Bullock, Hannah, Durakovic, Umjia, Gately, Jon, Hurst, Sheldon G., IV, Jackobeck, Ryan, Janicki, Erik, Michaels, Brandye, Rowedder, Holli, Tisa, Louis S.   +9 more
core   +2 more sources

Formation of Aberrant Myotubes by Myoblasts Lacking Myosin VI Is Associated with Alterations in the Cytoskeleton Organization, Myoblast Adhesion and Fusion

Cells, 2020
We have previously postulated that unconventional myosin VI (MVI) could be involved in myoblast differentiation. Here, we addressed the mechanism(s) of its involvement using primary myoblast culture derived from the hindlimb muscles of Snell’s waltzer ...
Lilya Lehka, Małgorzata Topolewska, Dominika Wojton, Olena Karatsai, Paloma Alvarez-Suarez, Paweł Pomorski, Maria Jolanta Rędowicz   +6 more
doaj   +1 more source

Syntaphilin controls a mitochondrial rheostat for proliferation-motility decisions in cancer. [PDF]

, 2017
Tumors adapt to an unfavorable microenvironment by controlling the balance between cell proliferation and cell motility, but the regulators of this process are largely unknown.
Ashani T. Weeraratna, Caino, Chae, Chandran, Dario C. Altieri, Dayana B. Rivadeneira, Dmitry I. Gabrilovich, Dong, Eui Tae Kim, Gao, Hecht, Hwang, Jae Ho Seo, Kim, LeBleu, Lucia R. Languino, M. Cecilia Caino, Yuan Wang   +17 more
core   +2 more sources