Results 81 to 90 of about 843,128 (402)

The Saccharomyces cerevisiae amino acid transporter Lyp1 has a broad substrate spectrum

FEBS Letters, EarlyView.
In Saccharomyces cerevisiae, Yeast Amino acid Transporter family members mediate the import of amino acids, ranging from substrate specialists to generalists. Here, we show that the specialist transporter, Lyp1, has a broader substrate spectrum than previously described, with affinity constants spanning from micromolar to millimolar.
Foteini Karapanagioti, Sebastian Obermaier, Dirk J. Slotboom, Bert Poolman   +3 more
wiley   +1 more source

Logistic damping effect in chemotaxis models with density-suppressed motility [PDF]

arXiv, 2021
This paper is concerned with a parabolic-elliptic chemotaxis model with density-suppressed motility and general logistic source in an $n$-dimensional smooth bounded domain with Neumann boundary conditions. Under the minimal conditions for the density-suppressed motility function, we explore how strong the logistic damping can warrant the global ...
arxiv  

The myosin X motor is optimized for movement on actin bundles

Nature Communications, 2016
Myosin X is a molecular motor unique in its ability to generate filopodia, but the mechanism explaining this behaviour is not known. Here, through a combination of structure, single-molecule assays and modelling the authors show that myosin X is ...
Virginie Ropars, Zhaohui Yang, Tatiana Isabet, Florian Blanc, Kaifeng Zhou, Tianming Lin, Xiaoyan Liu, Pascale Hissier, Frédéric Samazan, Béatrice Amigues, Eric D. Yang, Hyokeun Park, Olena Pylypenko, Marco Cecchini, Charles V. Sindelar, H. Lee Sweeney, Anne Houdusse   +16 more
doaj   +1 more source

A random cell motility gradient downstream of FGF controls elongation of amniote embryos [PDF]

, 2009
Vertebrate embryos are characterized by an elongated antero-posterior (AP) body axis, which forms by progressive cell deposition from a posterior growth zone in the embryo.
A Czirók, A Czirók, A Lawson, AQ Cai, B Ciruna, Bertrand Bénazéraf, CH Waddington, Charles D. Little, DT Gillespie, E Amaya, EA Zamir, EA Zamir, HC Berg, I Araki, IF Sbalzarini, J Dubrulle, JB Charrier, MC Delfini, Nicolas Denans, NTJr Spratt, O Voiculescu, Olivier Pourquié, P Martin, P Rifes, PA Rupp, Paul Francois, PM Kulesa, R Bellairs, R Keller, RS Beddington, Ruth E. Baker, SC Chapman, T Watanabe, V Hamburger, X Sun, X Yang   +35 more
core   +3 more sources

The cytoskeletal control of B cell receptor and integrin signaling in normal B cells and chronic lymphocytic leukemia

FEBS Letters, EarlyView.
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley   +1 more source

Esophageal High Pressure Zones: Effect of Perisophageal Structures on Esophageal Manometric Recording

Canadian Journal of Gastroenterology, 1994
During the course of esophageal motility studies, short zones of elevated esophageal baseline pressure are occasionally noticed. The aim of this study is to determine their frequency and their cause. Among 77 consecutive esophageal manometries (group 1),
G Bédard, A Pellicano, R Ste-Marie
doaj   +1 more source

Inactivation of the major hemolysin gene influences expression of the nonribosomal peptide synthetase gene swrA in the insect pathogen Serratia sp. strain SCBI [PDF]

, 2017
Hemolysins are important virulence factors for many bacterial pathogens, including Serratia marcescens. The role of the major hemolysin gene in the insect pathogen Serratia sp.
Bode, Helge, LaCourse, Kaitlyn, Petersen, Lauren M., Schoner, Tim A., Tisa, Louis S.   +4 more
core   +2 more sources

Extraocular Muscle Imbalance and Outcomes of Scleral Buckling Surgery for Primary Rhegmatogenous Retinal Detachment [PDF]

, 2020
Objective: The objective was to study the muscle imbalance, restrictive motility in unlike gazes and the outcomes of the scleral buckling surgery for rhegmatogenous retinal detachment.
Kawish, A. B. (Ayesha), Nawaz, S. (Sadia), Tahir, Q. (Qandeel)   +2 more
core   +1 more source

Interferon-γ derived from cytotoxic lymphocytes directly enhances their motility and cytotoxicity

Cell Death and Disease, 2017
Interferon gamma (IFNγ) is a key moderator of cell-mediated immunity with diverse, mainly pro-inflammatory actions on immunocytes and target tissue. Recent studies have shown it may enhance anti-tumor and antiviral effects of CD8 T cells.
P. Bhat, G. Leggatt, N. Waterhouse, I. Frazer   +3 more
semanticscholar   +1 more source

Flow‐based immunomagnetic enrichment of circulating tumor cells from diagnostic leukapheresis product

Molecular Oncology, EarlyView.
The number of circulating tumor cells obtained from prostate cancer patients was increased approximately 5‐fold compared to regular CellSearch when processing 2 mL diagnostic leukapheresis material aliquots and increased by 44‐fold when processing 20 mL DLA aliquots using the flow enrichment target capture Halbach‐array.
Michiel Stevens, Anouk Mentink, Frank A. W. Coumans, Eshwari Dathathri, Khrystany T. Isebia, Jaco Kraan, Ronald de Wit, John W. M. Martens, Leon W. M. M. Terstappen   +8 more
wiley   +1 more source