Results 111 to 120 of about 4,393,309 (309)

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Simulated Research on the Influence of Thermal Conductivity of Stator Insulation System on Temperature Rise of Electric Motor

open access: yesKongzhi Yu Xinxi Jishu, 2017
At present, the development trend of motor such as downsize, light weight and high power density has put forward higher requirement to its insulation system.
YANG Jinxia   +3 more
doaj  

Action Semantic Deficits and Impaired Motor Skills in Autistic Adults Without Intellectual Impairment

open access: yesFrontiers in Human Neuroscience, 2019
Several studies indicate the functional importance of the motor cortex for higher cognition, language and semantic processing, and place the neural substrate of these processes in sensorimotor action-perception circuits linking motor, sensory and ...
Josephina Hillus   +3 more
doaj   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

MISIONES DE COHETERíA EXPERIMENTAL CON PROPELENTE SÓLIDO: MISIÓN SÉNECA, COHETE AINKAA 1

open access: yesCiencia e Ingeniería Neogranadina, 2010
Este documento expone la metodología y los resultados obtenidos en el desarrollo de una investigación sistemática, que trata sobre a la implementación de misiones de cohetería experimental.
José Alejandro Urrego Peña   +1 more
doaj  

Investigation of Motor Supply Signature Analysis to Detect Motor Resistance Imbalances [PDF]

open access: yes, 2015
The trend to use inverter drives in industry is well established. It is desirable to monitor the condition of the motor/drive combination with the minimum of system intervention and at the same time retaining compatibility with the latest generation of ...
Ashari, Djoni   +3 more
core  

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Motor run-up system [PDF]

open access: yes, 1975
A starting system is described for bringing a large synchronous motor up to speed to prevent large power line disturbances at the moment the motor is connected to the power line.
Daeges, J. J.
core   +1 more source

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