Results 31 to 40 of about 173,723 (245)

What can we learn from the effect of trihexyphenidyl on motor fluctuations during continuous levodopa-carbidopa intestinal gel infusion (LCIG)? – First documented case

Clinical Parkinsonism & Related Disorders, 2020
Motor fluctuations can be seen even during treatment with continuous levodopa-carbidopa intestinal gel infusion (LCIG). We report on a middle-aged man with advanced Parkinson's disease (PD) on LCIG in which motor fluctuations have been improved with an ...
Shin-ichiro Kubo, Ken Nakamura, Yoshimasa Tada, Nobuyuki Kashio, Shinya Yamashita   +4 more
doaj   +1 more source

Freezing of Gait in Parkinson’s Disease: Risk Factors, Their Interactions, and Associated Nonmotor Symptoms

Parkinson's Disease, 2021
Background. Freezing of gait (FOG) is a debilitating and incompletely understood symptom in Parkinson’s disease (PD). Objective. To determine the principal clinical factors predisposing to FOG in PD, their interactions, and associated nonmotor symptoms ...
David Gordon Lichter, Ralph Holmes Boring Benedict, Linda Ann Hershey   +2 more
doaj   +1 more source

New treatments for levodopa‐induced motor complications

Movement Disorders, 2015
AbstractLevodopa (l‐dopa)‐induced motor complications, including motor fluctuations and dyskinesia, affect almost all patients with Parkinson's disease (PD) at some point during the disease course, with relevant implications in global health status. Various dopaminergic and nondopaminergic pharmacological approaches as well as more invasive strategies ...
Rascol, Olivier, Pérez Lloret, Santiago, Ferreira, Joaquim   +2 more
openaire   +3 more sources

Health‐Related Social Needs in Children With Sickle Cell Disease Are Associated With Worse Health‐Related Quality of Life

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Children with sickle cell disease (SCD) face multiple acute and chronic medical complications that may impact their quality of life as reported by patients themselves. Health‐related social needs (HRSNs), such as food and housing insecurity, are common in people with SCD, but the association between HRSNs and patient‐reported ...
Sarah J. Marks, Molly Sonenklar, Cerelia Donald, Cecelia Valrie, Wally Smith, India Sisler   +5 more
wiley   +1 more source

Early Impact of Childhood Opportunity on Neurocognitive Outcomes in Sickle Cell Disease

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Neurocognitive impairment is a well‐recognized complication of sickle cell disease (SCD) that begins early in childhood and persists across development. While cerebrovascular injury contributes substantially to risk, neurocognitive deficits are also observed in children without overt or silent cerebral infarctions, suggesting ...
Julia E. LaMotte, Hannah Koch, Olivia A. Coughlin, Jillian R. Bouck, Allie Carter, Seethal A. Jacob   +5 more
wiley   +1 more source

Analysis of Complications Following Distal Ankle Nerve Blocks for Foot and Ankle Procedures

Foot & Ankle Orthopaedics, 2022
Category: Ankle; Arthroscopy; Bunion; Hindfoot; Midfoot/Forefoot; Other Introduction/Purpose: Popliteal nerve blocks are a common procedure employed by anesthesiologists to augment intraoperative anesthesia and provide postoperative pain control ...
Ania Bartholomew, Tyler Slone, Michael Ciesa, Nicholas A. Cheney DO, Brian C. Clark   +4 more
doaj   +1 more source

Childhood Acute Lymphoblastic Leukemia Survival in Western Kenya: Reduction in Early Deaths and Treatment Abandonment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background An earlier study on children diagnosed with acute lymphoblastic leukemia (ALL) at Moi Teaching and Referral Hospital (MTRH) in Kenya reported a low event‐free survival (EFS), excess treatment abandonment, and high induction mortality.
Gilbert Olbara, George Bogonko, Festus Njuguna, Sandra Langat, Martha Kipngetich, Dennis Njenga, Gertjan Johannes Kaspers, Terry Allen Vik   +7 more
wiley   +1 more source

Dysphagia for medication in Parkinson’s disease

npj Parkinson's Disease, 2022
Dysphagia is common in Parkinson’s disease (PD) and is assumed to complicate medication intake. This study comprehensively investigates dysphagia for medication and its association with motor complications in PD.
Bendix Labeit, Elijahu Berkovich, Inga Claus, Malte Roderigo, Anna-Lena Schwake, Dvora Izgelov, Dorit Mimrod, Sigrid Ahring, Stephan Oelenberg, Paul Muhle, Verena Zentsch, Fiona Wenninger, Sonja Suntrup-Krueger, Rainer Dziewas, Tobias Warnecke   +14 more
doaj   +1 more source

Inpatient Exposure, Confidence, and Knowledge in Pediatric Hematology/Oncology: Evaluating General Pediatric Residents During 2025 ACGME Curriculum Change

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background General pediatricians often evaluate hematologic and oncologic presentations before subspecialty consultation, yet the 2025 Accreditation Council for Graduate Medical Education (ACGME) pediatric requirements reduce inpatient pediatric hematology/oncology (PHO) time, raising questions about resident readiness.
Colburn Yu, Rohini Jain
wiley   +1 more source

Exploring the relationships between clinical manifestations and sex hormones, thyroid hormones, and menstrual factors in female Parkinson’s disease patients

Frontiers in Medicine
BackgroundParkinson’s disease (PD) affects both sexes, but there are notable differences in its clinical manifestations and management in women.ObjectiveThis study aimed to compare variations in sex and thyroid hormone levels and menstrual factors ...
Fan Wang, Jing Zhao, Jichen Du, Jilai Li, Peifu Wang, Zhong Yi, Tao Feng, Zhirong Wan   +7 more
doaj   +1 more source