Results 171 to 180 of about 701,388 (349)

Characterization of the Schizosaccharomyces pombe orthologue of the human survival motor neuron (SMN) protein [PDF]

, 2000
Nicholas Owen
openalex   +1 more source

Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models

Molecular Oncology, EarlyView.
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon, Moa Stenudd, Margherita Zamboni, Kanar Alkass, Carl‐Johan Eriksson, Lars Pedersen, Alrik Schörling, Anna Thoss, Anders Bergh, Pernilla Wikström, Hans‐Olov Adami, Henrik Toft Sørensen, Henrik Druid, Jonas Frisén   +13 more
wiley   +1 more source

Single particle cryo-EM structure of the outer hair cell motor protein prestin. [PDF]

Nat Commun, 2022
Butan C, Song Q, Bai JP, Tan WJT, Navaratnam D, Santos-Sacchi J.   +5 more
europepmc   +1 more source

Cyclin D1 and Cdk4 Protein Induction in Motor Neurons After Transient Spinal Cord Ischemia in Rabbits [PDF]

, 2000
Masahiro Sakurai, Takeshi Hayashi, Koji Abe, Yasuto Itoyama, Koichi Tabayashi   +4 more
openalex   +1 more source

Association of high‐dose radioactive iodine therapy with PPM1D‐mutated clonal hematopoiesis in older individuals

Molecular Oncology, EarlyView.
In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim, Sungwoo Bae, Jaeyong Choi, Sun‐Wha Im, Bukyoung Cha, Gyeongseo Jung, Sun Wook Cho, Eul‐Ju Seo, Young Ah Lee, Jin Chul Paeng, Young Joo Park, Jong‐Il Kim   +11 more
wiley   +1 more source

Inhibitions and Down-Regulation of Motor Protein Eg5 Expression in Primary Sensory Neurons Reveal a Novel Therapeutic Target for Pathological Pain. [PDF]

Neurotherapeutics, 2022
Wei N, Yu Y, Yang Y, Wang XL, Zhong ZJ, Chen XF, Yu YQ.   +6 more
europepmc   +1 more source

The neuron-specific kinesin superfamily protein KIF1A is a uniqye monomeric motor for anterograde axonal transport of synaptic vesicle precursors

, 1995
Yasushi Okada, Hiroto Yamazaki, Yoko Sekine‐Aizawa, Nobutaka Hirokawa   +3 more
openalex   +1 more source

Coupling ion specificity of chimeras between H⁺- and Na⁺-driven motor proteins, MotB and PomB, inVibriopolar flagella [PDF]

, 2000
Yukako Asai, Ikuro Kawagishi, R. Elizabeth Sockett, Michio Homma   +3 more
openalex   +1 more source

ITGAV and SMAD4 influence the progression and clinical outcome of pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
In SMAD4‐positive pancreatic ductal adenocarcinoma (PDAC), integrin subunit alpha V (ITGAV) activates latent TGF‐β, which binds to the TGF‐β receptor and phosphorylates SMAD2/3. The activated SMAD2/3 forms a complex with SMAD4, and together they translocate to the nucleus, modulating gene expression to promote proliferation, migration, and invasion. In
Daniel K. C. Lee, Keyue Chen, Ryan Loke, Xiang Li, David Liubart, Golam T. Saffi, Jonathan T. S. Chow, Ché M. P. Melo, Lydia To, Leonardo Salmena   +9 more
wiley   +1 more source

The Arabidopsis thaliana Kinesin-5 AtKRP125b Is a Processive, Microtubule-Sliding Motor Protein with Putative Plant-Specific Functions. [PDF]

Int J Mol Sci, 2021
Strauß T, Schattner S, Hoth S, Walter WJ.   +3 more
europepmc   +1 more source