Results 181 to 190 of about 438,155 (307)

Changes in the Number of Molecular Motors Driving Vesicle Transport in PC12

, 2003
Motor proteins such as kinesin and dynein drive vesicle transport within cells by converting the chemical energy of ATP into mechanical work. Though isolated kinesin has been well studied in in-vitro assays, little is known of the performance of the ...
Hill, David Brooks
core  

MiR-140-3p regulates axonal motor protein KIF5A and contributes to axonal transport degeneration in SMA. [PDF]

Cell Death Discov
Baklou M, Valsecchi V, Laudati G, Kolici X, Brancaccio P, De Iesu N, Anzilotti S, Cieri F, Pignataro G.   +8 more
europepmc   +1 more source

Acinetobacter baylyi regulates type IV pilus synthesis by employing two extension motors and a motor protein inhibitor. [PDF]

Nat Commun, 2021
Ellison CK, Dalia TN, Klancher CA, Shaevitz JW, Gitai Z, Dalia AB.   +5 more
europepmc   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

The kinesin-14 family motor protein KIFC2 promotes prostate cancer progression by regulating p65. [PDF]

J Biol Chem
Liu X, Lin Y, Long W, Yi R, Zhang X, Xie C, Jin N, Qiu Z, Liu X.   +8 more
europepmc   +1 more source

Molecular motor protein KIF5C mediates structural plasticity and long-term memory by constraining local translation. [PDF]

Cell Rep, 2021
Swarnkar S, Avchalumov Y, Espadas I, Grinman E, Liu XA, Raveendra BL, Zucca A, Mediouni S, Sadhu A, Valente S, Page D, Miller K, Puthanveettil SV.   +12 more
europepmc   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Development of a prostate cancer biochemical recurrence risk signature using machine learning and motor protein-related genes. [PDF]

PLoS One
Wang W, Xie G, Wu Z.
europepmc   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source

The Plus End-Directed Microtubule (Kinesin-3 Family) Motor Protein KIF13B Is Associated with the Photoreceptor Synaptic Ribbon Complex. [PDF]

Int J Mol Sci
Suiwal S, Schwarz K, Maxeiner S, Schmitz F.   +3 more
europepmc   +1 more source