Kinesin-like motor protein KIF23 maintains neural stem and progenitor cell pools in the developing cortex. [PDF]
Naher S +8 more
europepmc +1 more source
Correction for Tachiyama et al., The flagellar motor protein FliL forms a scaffold of circumferentially positioned rings required for stator activation. [PDF]
europepmc +1 more source
FtsK Is a DNA Motor Protein that Activates Chromosome Dimer Resolution by Switching the Catalytic State of the XerC and XerD Recombinases [PDF]
Laurent Aussel +5 more
openalex +1 more source
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Gephyrin Interacts with Dynein Light Chains 1 and 2, Components of Motor Protein Complexes [PDF]
Jens C. Fuhrmann +8 more
openalex +1 more source
Using multi‐omic characterization, we aimed to identify key regulators specific to squamous cell lung carcinoma (SqCC). SqCC‐specific differentially expressed genes were integrated with metabolics data. High expression of the creatine transporter SLC6A8, along with elevated creatine levels, appeared to be a distinct metabolic feature of SqCC.
Johan Staaf +10 more
wiley +1 more source
The Actin Motor Protein Myosin 6 Contributes to Cell Migration and Expression of GIPC1 and Septins in Breast Cancer Cells. [PDF]
Izdebska M +5 more
europepmc +1 more source
The SecA ATPase motor protein binds to Escherichia coli liposomes only as monomers. [PDF]
Roussel G, White SH.
europepmc +1 more source
Overexpression of motor protein KIF17 enhances spatial and working memory in transgenic mice [PDF]
Richard W. Wong +4 more
openalex +1 more source
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source

