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Targeting of Motor Proteins [PDF]

open access: possibleScience, 1996
Microtubules are responsible for chromosome segregation and the movement and reorganization of membranous organelles. Many aspects of microtubule-based motility can be attributed to the action of motor proteins, producing force directed toward either end of microtubules.
Michael P. Sheetz, Richard B. Vallee
openaire   +2 more sources

Rotary protein motors [PDF]

open access: possibleTrends in Cell Biology, 2003
Three protein motors have been unambiguously identified as rotary engines: the bacterial flagellar motor and the two motors that constitute ATP synthase (F(0)F(1) ATPase). Of these, the bacterial flagellar motor and F(0) motors derive their energy from a transmembrane ion-motive force, whereas the F(1) motor is driven by ATP hydrolysis. Here, we review
George Oster, Hongyun Wang
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Motor Proteins and Spermatogenesis

2021
Unlike the intermediate filament- and septin-based cytoskeletons which are apolar structures, the microtubule (MT) and actin cytoskeletons are polarized structures in mammalian cells and tissues including the testis, most notable in Sertoli cells. In the testis, these cytoskeletons that stretch across the epithelium of seminiferous tubules and lay ...
Xiaolong Wu   +7 more
openaire   +3 more sources

Yeast motor proteins

Folia Microbiologica, 1995
Yeast accomplish a variety of intracellular motile events with the aid of mechanochemical enzymes known as motor proteins. This review covers the current state of knowledge on myosins, kinesins, dyneins, dynamins and SMC proteins present in yeast cells, and the most important developments in the study of yeast mitosis.
R. Bonaly, Eva Streiblová
openaire   +3 more sources

Motor proteins transporting cargos

The European Physical Journal E, 2005
Processive motor proteins such as kinesin and myosin-V are enzymes that use the energy of ATP hydrolysis to travel along polar cytoskeletal filaments. One of the functions of these proteins is the transport of vesicles and protein complexes that are linked to the light chains of the motors. Modeling the light chain by a linear elastic spring, and using
Zeldovich, K. B.   +2 more
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Motor neurons rely on motor proteins

Trends in Cell Biology, 2004
The importance of active axonal transport to the neuron has been highlighted by the recent discoveries that mutations in microtubule motor proteins result in neurodegenerative diseases. Mutations affecting microtubule motor function have been shown to cause hereditary forms of Charcot-Marie-Tooth disease (type 2A), hereditary spastic paraplegia and ...
openaire   +3 more sources

Towards a microrotary motor driven by motor proteins

2007 IEEE 20th International Conference on Micro Electro Mechanical Systems (MEMS), 2007
Biological molecular motors, motor proteins, have a number of unique advantages over artificial motors, including efficient conversion of chemical energy into mechanical work and the potential for self-assembly into larger structures. This paper describes a bio- hybrid micro rotary motor using kinesin/ microtubule motor.
Shoji Takeuchi, Yuichi Hiratsuka
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Motor Proteins at Work for Nanotechnology

Science, 2007
The biological cell is equipped with a variety of molecular machines that perform complex mechanical tasks such as cell division or intracellular transport. One can envision employing these biological motors in artificial environments. We review the progress that has been made in using motor proteins for powering or manipulating nanoscale components ...
Martin G. L. van den Heuvel, Cees Dekker
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The protein import motor of mitochondria [PDF]

open access: possibleNature Reviews Molecular Cell Biology, 2002
Proteins that are destined for the matrix of mitochondria are transported into this organelle by two translocases: the TOM complex, which transports proteins across the outer mitochondrial membrane; and the TIM23 complex, which gets them through the inner mitochondrial membrane. Two models have been proposed to explain how this protein-import machinery
Michael Brunner, Walter Neupert
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The Mitochondrial Protein Import Motor

Biological Chemistry, 2000
Mitochondrial proteins are synthesized as precursor proteins in the cytosol and are posttranslationally imported into the organelle. A complex system of translocation machineries recognizes and transports the precursor polypeptide across the mitochondrial membranes.
Strub, Andreas   +3 more
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