Results 221 to 230 of about 498,521 (337)

Multiscale molecular dynamics simulations of rotary motor proteins. [PDF]

Biophys Rev, 2018
Ekimoto T, Ikeguchi M.
europepmc   +1 more source

A Model of Microtubule Organization in the Presence of Motor Proteins [PDF]

, 2018
de Vries, Gerda
core   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Defective recruitment of motor proteins to autophagic compartments contributes to autophagic failure in aging. [PDF]

Aging Cell, 2018
Bejarano E, Murray JW, Wang X, Pampliega O, Yin D, Patel B, Yuste A, Wolkoff AW, Cuervo AM.   +8 more
europepmc   +1 more source

1A1-T04 An optical device powered by biological molecular motors : Device assembly from protein components(MEMS and Nano-Technology)

, 2012
Yoshiyasu Usami, Ayumu Miyata, Y. Hiratsuka, T. Nitta   +3 more
openalex   +2 more sources

MEA6 Deficiency Impairs Cerebellar Development and Motor Performance by Tethering Protein Trafficking [PDF]

, 2019
Xin‐Tai Wang, Xinyu Cai, Fang‐Xiao Xu, Lin Zhou, Rui Zheng, Kuang-Yi Ma, Zhiheng Xu, Ying Shen   +7 more
openalex   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Run-and-pause dynamics of cytoskeletal motor proteins. [PDF]

Sci Rep, 2016
Hafner AE, Santen L, Rieger H, Shaebani MR.   +3 more
europepmc   +1 more source

Mechanical Design of Translocating Motor Proteins

, 2009
Wonmuk Hwang, Matthew J. Lang
openalex   +2 more sources

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source