Results 251 to 260 of about 498,521 (337)
Sensing surface mechanical deformation using active probes driven by motor proteins. [PDF]
Nat Commun, 2016 Inoue D +6 more
europepmc +1 more source
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Correction: Distribution and evolution of stable single α-helices (SAH domains) in myosin motor proteins. [PDF]
PLoS One, 2017 Simm D, Hatje K, Kollmar M.
europepmc +1 more source
Driving cancer: Motor and adaptor protein dysregulation in endocytic receptor signalling
David H. Kim +3 more
openalex +1 more source
Construction of a Chassis for a Tripartite Protein-Based Molecular Motor
, 2017 Lara Siobhan Rebecca Small +9 more
openalex +1 more source
Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity
Molecular Oncology, EarlyView.Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek +2 more
wiley +1 more source
The presenilin loop region is essential for glycogen synthase kinase 3 β (GSK3β) mediated functions on motor proteins during axonal transport. [PDF]
Hum Mol Genet, 2018 Banerjee R +4 more
europepmc +1 more source
Molecular Oncology, EarlyView.To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley +1 more source