Results 41 to 50 of about 508,706 (358)
Molecular Oncology, EarlyView.C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald +18 more
wiley +1 more source
Efficiency assessment of different highspeed tracked vehicle hybrid powertrain conceptions
Vojnotehnički GlasnikIntroduction/purpose: Increased development of hybrid powertrains during the last decade brought high-speed tracked vehicles into the same spotlight as commercial and passenger hybrid vehicles.
Luka M. Ponorac, Ivan A. Blagojević
doaj +1 more source
In-wheel axial-flux SRM drive for light electric vehicles [PDF]
, 2018 Revenues from global sales of light electric vehicles are expected to grow from $ 9.3 billion in 2017 to $ 23.9 billion in 2025. In order to boost this growth electric drives with better features and lower costs have to be developed.
Andrada Gascón, Pedro +5 more
core
Molecular Oncology, EarlyView.TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach +8 more
wiley +1 more source
Quality Tests of Hybrid Joint–Clinching and Adhesive—Case Study
Applied Sciences, 2022 Inseparable joints are widely used in machine and vehicle construction. Hybrid joints include bonding with sheet metal clinching. This combination reduces costs as well as the time of production compared to welded joints.
Jakub Kowalczyk +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Cotargeting EGFR and STAT3 with Erlotinib and TTI‐101 impairs both 2D and 3D growth of ETV1‐overexpressing prostate cancer cells by disrupting a self‐sustaining ETV1–EGFR positive feedback loop that promotes EGFR and STAT3 expression and phosphorylation (activation).
Elsa Gomes Paiva +5 more
wiley +1 more source
Dynamic Modelling of Piston the Motion in Combustion Engines
Communications, 2022 The presented work discusses a methodology for analysis of noise emissions from a diesel engine. A numerical model of the piston motion, analyzing its lateral, reciprocating and rotation motion, has been presented in order to investigate the lateral ...
Sunny Narayan +6 more
doaj +1 more source
Molecular Oncology, EarlyView.Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon +13 more
wiley +1 more source
R455A Refrigerant as a Prospective Working Fluid in Refrigeration Systems for Gastronomy Furnishings
EnergiesThe general development of technology and universal access means that gastronomy furnishings can be found in every corner of the world. Therefore, it is important to develop these devices and the machines that constitute them.
Tomasz Bernat, Krzysztof Bieńczak
doaj +1 more source
Journal of Sustainable Development of Energy, Water and Environment Systems, 2017 Compressed natural gas can be used in diesel engine with great benefits, but because of its low reactivity it is usually used in a so called dual fuel combustion process.
Mario Sremec +3 more
doaj +1 more source