Results 111 to 120 of about 96,662 (219)
International Journal of Biological Sciences, 2007 To characterize the role of BRCA1 in mammary gland development and tumor suppression, a transgenic mouse model of BRCA1 overexpression was developed. Using the mouse mammary tumor virus (MMTV) promoter/enhancer, transgenic mice expressing human BRCA1 or ...
Arichika Hoshino, Cindy J. Yee, Mel Campbell, Randall L. Woltjer, Rebecca L. Townsend, Riet van der Meer, Yu Shyr, Jeffrey T. Holt, Harold L. Moses, Roy A. Jensen
doaj
State‐of‐the‐Art Strategies for Circular RNA in Cancers: Opportunity and Challenge
MedComm, Volume 7, Issue 2, February 2026.Overview of circular RNA in tumors. ABSTRACT Circular RNAs (circRNAs) are characterized by their covalently closed structure, remarkable stability, and precise spatiotemporal regulation, evolving from once‐overlooked transcriptional byproducts to pivotal molecular regulators.
Zehao Ding +6 more
wiley +1 more source
AnimalsCompared to the number of studies on the neoplasms of laboratory rodents, fewer studies have focused on spontaneous neoplasms in pet rodents. Notably, the mouse mammary tumor virus (MMTV) is associated with mammary tumors in rodents.
Ya-Mei Chen, Jia-Ling Wu, Wei-Hao Lin
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Protease‐mediated maturation of M‐PMV reverse transcriptase into a functional heterodimer
Protein Science, Volume 35, Issue 2, February 2026.Abstract Reverse transcriptase (RT) of retroviruses orchestrates viral replication, yet its structural diversity remains poorly understood. Well‐studied RTs, such as those from HIV‐1, murine leukemia virus, and avian myeloblastosis virus, were characterized decades ago, but less prominent retroviruses have escaped detailed analysis.
Marina Kapisheva +6 more
wiley +1 more source
The FEBS Journal, Volume 293, Issue 3, Page 709-728, February 2026.CLEC18A is a previously poorly characterized C‐type lectin. We mapped the expression of CLEC18A to the proximal tubule of the kidney and found CLEC18A to interact with sulfated glycosaminoglycans on proteoglycans. Furthermore, we found that CLEC18A plays an important role in hindering the progression of clear cell renal cell carcinomas in humans and in
Gustav Jonsson +10 more
wiley +1 more source
Involvement of APOBEC3A/B Deletion in Mouse Mammary Tumor Virus (MMTV)-like Positive Human Breast Cancer. [PDF]
Diagnostics (Basel), 2023 de Sousa Pereira N +2 more
europepmc +1 more source
Mouse Mammary Tumor Virus: New Tumor Virus or Just a Rumor Virus? [PDF]
JNCI Journal of the National Cancer Institute, 2009 W hen German microbiologist Harald zur Hausen, M.D., D.Sc., hypothesized in 1974 that human papillomavirus (HPV) played a central role in causing cervical cancer, few took him seriously. But in 1983 he discovered HPV-16, and a year later, HPV-18 in tumors of cervical cancer patients — findings that led eventually to the first preventive cancer vaccine ...
openaire +1 more source
Tissue-specific and ubiquitous factors binding next to the glucocorticoid receptor modulate transcription from the mouse mammary tumor virus promoter [PDF]
, 1995 Steroid hormones complexed with their receptors play an essential role in the regulation of mouse mammary tumor virus (MMTV) transcription. However, the need for additional tissue-specific regulatory factors is suggested by the lack of virus expression ...
Buetti, E., Cavin, C.
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Kemiripan Sekuen Mouse Mammary Tumor Virus dengan Human Mammary Tumor Virus pada Kanker Payudara
Jurnal Kedokteran Meditek, 2014 Abstrackhuman breast cancer incidence varied around the world, where the incidence in Asia is lower than western. Different types if mice in both parts of the world suggestive associated with the incidence of human breast cancer, in which M.domesticus the main carrier of virus more widely available in western. Mouse Mammary Tumor Virus (MMTV) is a type
Shintia Christina, Puspita Eka Wuyung
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Targeting matriptase in breast cancer abrogates tumour progression via impairment of stromal-epithelial growth factor signalling. [PDF]
, 2015 Matriptase is an epithelia-specific membrane-anchored serine protease that has received considerable attention in recent years because of its consistent dysregulation in human epithelial tumours, including breast cancer.
Bergum, Christopher +11 more
core +1 more source