Goniothalamin (GTN) exerts anticancer effects by promoting reactive oxygen species (ROS) generation, glutathione (GSH) depletion, DNA damage, endoplasmic reticulum (ER) stress, and mitochondrial dysfunction. These interconnected events trigger apoptosis, necroptosis, anoikis, and autophagy, while modulating mitogen‐activated protein kinase (MAPK ...
Nataša Joković +6 more
wiley +1 more source
Deletion of Vβ3<sup>+</sup>CD4<sup>+</sup> T cells by endogenous mouse mammary tumor virus 3 prevents type 1 diabetes induction by autoreactive CD8<sup>+</sup> T cells. [PDF]
Ye C +7 more
europepmc +1 more source
SIRT Family: Biological Functions and Therapeutic Targets
SIRT1–SIRT7 networks from transgenic mice to human‑relevant therapeutic targets. SIRT1–SIRT7 form an isoform‑, organ‑, and disease‑specific regulatory network. Transgenic Sirt1–7 mouse models define central regulatory SIRTs (SIRT1, SIRT3, SIRT6), context‑dependent modifiers (SIRT2, SIRT4, SIRT5, SIRT7), and their key mechanisms and target organs. These
Jia‐Yi Wang +9 more
wiley +1 more source
Thermodynamics of unfolding mechanisms of mouse mammary tumor virus pseudoknot from a coarse-grained loop-entropy model. [PDF]
Tang K +4 more
europepmc +1 more source
Machine Learning of Personal Repertoires From Public T Cell Receptors
ABSTRACT The T‐cell receptor (TCR) repertoire records an individual's immunological history, but most unique CDR3 sequences in any one person are private and uninformative about anyone else. A small subset, however, recurs predictably across unrelated donors.
Or Malca, Alona Zilberberg, Sol Efroni
wiley +1 more source
Molecular characterization of human papillomavirus and mouse mammary tumor virus-like infections in prostate cancer tissue and relevance with tumor characteristics. [PDF]
Abumsimir B +9 more
europepmc +1 more source
Wingless-type mouse mammary tumor virus integration site regulation of bovine theca cells. [PDF]
Spicer LJ.
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The Role Of Mouse Mammary Tumor Virus In The Induction And Progression Of Mouse Mammary Tumors [PDF]
Mouse mammary tumor virus (MMTV) is a retrovirus which causes mammary tumors in many strains of mice. An essential part of the viral life cycle involves the integration of a double-stranded DNA provirus into the host cell genome. Tumorigenesis is thought to be mediated by such integrated proviruses.;Restriction endonuclease analysis of the DNA from a ...
openaire
Effects of thermal stress and mechanistic target of rapamycin and wingless-type mouse mammary tumor virus integration site family pathways on the proliferation and differentiation of satellite cells derived from the breast muscle of different chicken lines. [PDF]
Xu J, Velleman SG.
europepmc +1 more source
A purine loop and the primer binding site are critical for the selective encapsidation of mouse mammary tumor virus genomic RNA by Pr77Gag. [PDF]
Chameettachal A +9 more
europepmc +1 more source

