Results 111 to 120 of about 63,529 (225)
Subset of spleen lymphocytes from BALB/cCrgl mice stimulated by mouse mammary tumor virus
Lymphocytes from BALB/cCrgl mice react to mouse mammary tumor virus-associated antigen(s) when tested in in vitro blastogenic transformation assays. These mice have a low incidence (less than 1%) of spontaneous mammary tumors and are free from complete ...
Charyulu, V, Lopez, D M, Sigel, M M
core
Interplays between mouse mammary tumor virus and the cellular and humoral immune response
Mouse mammary tumor virus has developed strategies to exploit the immune response. It requires vigorous immune stimulation to achieve efficient infection.
MacLennan, I C +21 more
core +1 more source
The retrovirus mouse mammary tumor virus is present in mouse strains with a high incidence of mammary tumors as a causative agent. It is produced mainly in the mammary glands of sexually mature females and is milk-transmitted to newborns. The fate of the
BEVILACQUA, GENEROSO +2 more
core
Deletion of Vβ3<sup>+</sup>CD4<sup>+</sup> T cells by endogenous mouse mammary tumor virus 3 prevents type 1 diabetes induction by autoreactive CD8<sup>+</sup> T cells. [PDF]
Ye C +7 more
europepmc +1 more source
Organoids: From Bench to Bedside Applications
Organoids, as a groundbreaking biomedical research platform, utilize adult stem cells (ASCs), embryonic stem cells (ESCs), and induced pluripotent stem cells (iPSCs) as sources. By integrating specific growth and differentiation signals within an extracellular matrix (e.g., Matrigel), organoids guide cells to self‐assemble into three‐dimensional ...
Kelin Li +6 more
wiley +1 more source
B and T cells are required for mouse mammary tumor virus spread within the mammary gland.
Mouse mammary tumor virus (MMTV) is an infectious retrovirus transmitted through milk from mother to newborns. MMTV encodes a superantigen (SAg) whose activity is indispensable for the virus life cycle, since a genetically engineered virus with a ...
Golovkina, T V, Ross, S R, Dudley, J P
core
Dmp1α inhibits HER2/neu-induced mammary tumorigenesis.
Our recent study shows a pivotal role of Dmp1 in quenching hyperproliferative signals from HER2 to the Arf-p53 pathway as a safety mechanism to prevent breast carcinogenesis.
Elizabeth A Fry +5 more
doaj +1 more source
Thermodynamics of unfolding mechanisms of mouse mammary tumor virus pseudoknot from a coarse-grained loop-entropy model. [PDF]
Tang K +4 more
europepmc +1 more source
White adipose tissue undergoes browning under endogenous and exogenous stimuli, primarily regulated by core molecules such as PRDM16 and UCP1. It exhibits a double‐edged sword effect in metabolic diseases and tumors: while mitigating metabolic disease impacts and suppressing early‐stage tumors through nutritional competition, it may accelerate cachexia
Yingjiao Wang +12 more
wiley +1 more source
A Novel Mechanism of Resistance to Mouse Mammary Tumor Virus Infection
Exogenous mouse mammary tumor virus (MMTV) is carried from the gut of suckling pups to the mammary glands by lymphocytes and induces mammary gland tumors. MMTV-induced tumor incidence in inbred mice of different strains ranges from 0 to as high as 100%
Tatyana V. Golovkina, Golovkina, T V
core +1 more source

