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Gene order of the mouse mammary tumor virus glycoproteins
Virology, 1977Immunochemical and tryptic peptide mapping techniques were used to show that the mouse mammary tumor virus (MMTV) envelope glycoproteins gp52 and gp36 are distinct components derived from a common glycosylated precursor polypeptide of 75,000 daltons (gPr75). Because both gp52 and gp36 are derived from a common precursor polypeptide and therefore have a
G, Schochetman +3 more
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Mouse mammary tumor virus as a model for viral carcinogenesis
Journal of Toxicology and Environmental Health, 1976Evidence is presented suggesting that genetic control may be the limiting factor in mammary tumor virus (MTV) positive mammary oncogenesis. Studies with hybrid mice involving high and low MTV-expressing murine strains suggest that expression of MTV in milk may not be as important in tumorigenesis as previously thought.
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Mouse Mammary Tumor Virus and Cancer
2011The retrovirus mouse mammary tumor virus (MMTV) was discovered in the 1930s as a milk-transmitted agent that causes breast cancer in mice. MMTV causes mammary tumors by insertional activation or mutation of cellular oncogenes. Some of the oncogenes activated by MMTV insertion have been also associated with human breast cancer.
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Cancer research, 1982
Seven spontaneous BALB/cfC3H mouse mammary tumors were heterogeneous in expression of murine mammary tumor virus-associated cell surface antigens. To determine the basis of this heterogeneity, cells from spontaneous tumors and from five subpopulations isolated from a single spontaneous tumor were examined for expression of viral antigens under both ...
Hager, J C, Heppner, G H
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Seven spontaneous BALB/cfC3H mouse mammary tumors were heterogeneous in expression of murine mammary tumor virus-associated cell surface antigens. To determine the basis of this heterogeneity, cells from spontaneous tumors and from five subpopulations isolated from a single spontaneous tumor were examined for expression of viral antigens under both ...
Hager, J C, Heppner, G H
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Mouse Mammary Tumor Virus Expression and Mammary Tumor Development
1983R, Michalides, A, van Ooyen, R, Nusse
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Molecular Aspects of Mouse Mammary Tumor Virus Biology
1987Publisher Summary This chapter outlines the structure and replication of the mouse mammary tumor virus (MMTV), and elaborates those aspects of MMTV molecular biology that have provided an insight into the understanding of gene regulation and virally induced carcinogenesis.
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Molecular Genetics of Mouse Mammary Tumor Virus
1983V, Traina-Dorge, J C, Cohen
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