Results 221 to 230 of about 2,749,540 (299)

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Systematic Evaluation of a Mouse Model of Aging-Associated Parkinson's Disease Induced with MPTP and D-Galactose. [PDF]

Biology (Basel)
Liu T, Liu X, Chen Q, Ren J, Li Z, Qiu X, Wang X, Wu L, Hu M, Chen D, Zhang H, Geng X.   +11 more
europepmc   +1 more source

A mouse model of GRIN2D developmental and epileptic encephalopathy recapitulates the human disease. [PDF]

Brain
Yam M, Nassir J, Galber D, Quinn S, Gal R, Ovadia M, Bordeynik-Cohen M, Peled E, Makinson CD, Hausman-Kedem M, Fattal-Valevski A, Frankel WN, Avraham KB, Rubinstein M.   +13 more
europepmc   +1 more source

Characterization of a Monogamous California Mouse Model of Chemotherapy. [PDF]

eNeuro
Seng MM, Tapp ZM, Glasper ER, Pyter LM.
europepmc   +1 more source

Consideration of sex as a biological variable over the history of the 5xFAD Alzheimer's Disease mouse model. [PDF]

Biol Sex Differ
Neuharth JI, Hernandez KS, Bernholtz J, Edwards H, Stewart A.   +4 more
europepmc   +1 more source

Construction and application of a humanized mouse model for prostate cancer in immunotherapy. [PDF]

Cancer Immunol Immunother
Guo W, Li H, Zhao Y, Qin J, Meng H, Ge X, Zhang C, Shi C.   +7 more
europepmc   +1 more source