Results 231 to 240 of about 1,832,552 (317)

Therapeutic Efficacy of Rapamycin in an Experimental Mouse Model of Corneal Alkali Burn. [PDF]

Int J Mol Sci
Bhujel B, Lee H, Chung HS, Kim JY.
europepmc   +1 more source

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

FEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source

Deficits in Forelimb Reach Learning in a Mouse Model of Fragile X Syndrome. [PDF]

eNeuro
Young LF, Derham A, Zhu R, Suvrathan A.
europepmc   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Transcriptional profiling of otic capsule and femur in the oim mouse model of osteogenesis imperfecta. [PDF]

JBMR Plus
Ayturk UM, Rogers M, Seide K, Oliver D, Chinenov Y, Aydin E, Carter EM, Raggio CL.   +7 more
europepmc   +1 more source

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

A clinically relevant mouse model for traumatic peripheral nerve injury and repair

Unterberger W, Rubisoier L, Schöffing F, Demetz E, Badurek S, Munck S, Schweigreiter R.   +6 more
europepmc   +1 more source

Early Amyloid Formation and Neuroinflammatory Response in a Bigenic Mouse Model Expressing Human α-Synuclein and Aβ. [PDF]

Parkinsons Dis
Thakore R, Aldén M, Gustavsson N, Danielson L, Lins L, Sánchez JD, Arensburg AR, Paulus A, da Silva IAN, Skoryk V, Kayed R, Gouras GK, Deierborg T, Heuer A, Konings SC, Klementieva O.   +15 more
europepmc   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source