Results 21 to 30 of about 2,749,540 (299)

Restoring Retinal Function in a Mouse Model of Hereditary Blindness [PDF]

open access: yes, 2005
Moore discusses a new study showing rescue of photoreceptor function using gene and drug therapies in a mouse model of Leber congenital ...
Moore, Tony
core   +4 more sources

Autoimmune Pancreatitis Mouse Model [PDF]

open access: yesCurrent Protocols in Immunology, 2018
AbstractAutoimmune pancreatitis (AIP) is a chronic fibro‐inflammatory disorder of the pancreas. However, extensive clinico‐pathological analyses have revealed that AIP is, in reality, a pancreatic manifestation of a newly described systemic disease known as IgG4‐related disease (IgG4‐RD).
Ken, Kamata   +4 more
openaire   +2 more sources

The dynamics of gene expression changes in a mouse model of oral tumorigenesis may help refine prevention and treatment strategies in patients with oral cancer. [PDF]

open access: yes, 2016
A better understanding of the dynamics of molecular changes occurring during the early stages of oral tumorigenesis may help refine prevention and treatment strategies.
Bertolus, Chloé   +14 more
core   +1 more source

Conditional Expression of Human 15-Lipoxygenase-1 in Mouse Prostate Induces Prostatic Intraepithelial Neoplasia: The FLiMP Mouse Model

open access: yesNeoplasia: An International Journal for Oncology Research, 2006
The incidence and mortality of prostate cancer (PCa) vary greatly in different geographic regions, for which lifestyle factors, such as dietary fat intake, have been implicated.
Uddhav P. Kelavkar   +3 more
doaj   +1 more source

Complement Properdin Determines Disease Activity in MRL/lpr Mice

open access: yesMedicina, 2020
Background and objects: In systemic lupus erythematosus, circulating immune complexes activate complement and, when trapped in renal capillaries, cause glomerulonephritis.
Hasanain Alaridhee   +4 more
doaj   +1 more source

A novel orthotopic mouse model replicates human lung cancer cachexia

open access: yesJournal of Cachexia, Sarcopenia and Muscle, 2023
Introduction Cancer cachexia, highly prevalent in lung cancer, is a debilitating syndrome characterized by involuntary loss of skeletal muscle mass and is associated with poor clinical outcome, decreased survival and negative impact on tumour therapy ...
Wouter R.P.H. van deWorp   +10 more
doaj   +1 more source

Translational relevance of behavioral, neural, and electroencephalographic profiles in a mouse model of post-traumatic stress disorder

open access: yesNeurobiology of Stress, 2021
Post-traumatic stress disorder (PTSD) is a severe, long-term psychological disorder triggered by distressing events. The neural basis and underlying mechanisms of PTSD are not completely understood.
Kaiwen Xi   +9 more
doaj   +1 more source

Awake chronic mouse model of targeted pial vessel occlusion via photothrombosis [PDF]

open access: yes, 2020
Animal models of stroke are used extensively to study the mechanisms involved in the acute and chronic phases of recovery following stroke. A translatable animal model that closely mimics the mechanisms of a human stroke is essential in understanding ...
Boas, David A.   +9 more
core   +1 more source

Seven-fluorochrome mouse M-FISH for high-resolution analysis of interchromosomal rearrangements [PDF]

open access: yes, 2003
The mouse has evolved to be the primary mammalian genetic model organism. Important applications include the modeling of human cancer and cloning experiments. In both settings, a detailed analysis of the mouse genome is essential.
Geigl, J.   +3 more
core   +1 more source

Olive polyphenol effects in a mouse model of chronic ethanol addiction [PDF]

open access: yes, 2017
Objectives Alcohol addiction elicits oxidative imbalance and it is well known that polyphenols possess antioxidant properties. We investigated whether or not polyphenols could confer a protective potential against alcohol-induced oxidative stress ...
Bello, Cristiano   +7 more
core   +1 more source

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