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Restoring Retinal Function in a Mouse Model of Hereditary Blindness [PDF]
Moore discusses a new study showing rescue of photoreceptor function using gene and drug therapies in a mouse model of Leber congenital ...
Moore, Tony
core +4 more sources
Autoimmune Pancreatitis Mouse Model [PDF]
AbstractAutoimmune pancreatitis (AIP) is a chronic fibro‐inflammatory disorder of the pancreas. However, extensive clinico‐pathological analyses have revealed that AIP is, in reality, a pancreatic manifestation of a newly described systemic disease known as IgG4‐related disease (IgG4‐RD).
Ken, Kamata +4 more
openaire +2 more sources
The dynamics of gene expression changes in a mouse model of oral tumorigenesis may help refine prevention and treatment strategies in patients with oral cancer. [PDF]
A better understanding of the dynamics of molecular changes occurring during the early stages of oral tumorigenesis may help refine prevention and treatment strategies.
Bertolus, Chloé +14 more
core +1 more source
The incidence and mortality of prostate cancer (PCa) vary greatly in different geographic regions, for which lifestyle factors, such as dietary fat intake, have been implicated.
Uddhav P. Kelavkar +3 more
doaj +1 more source
Complement Properdin Determines Disease Activity in MRL/lpr Mice
Background and objects: In systemic lupus erythematosus, circulating immune complexes activate complement and, when trapped in renal capillaries, cause glomerulonephritis.
Hasanain Alaridhee +4 more
doaj +1 more source
A novel orthotopic mouse model replicates human lung cancer cachexia
Introduction Cancer cachexia, highly prevalent in lung cancer, is a debilitating syndrome characterized by involuntary loss of skeletal muscle mass and is associated with poor clinical outcome, decreased survival and negative impact on tumour therapy ...
Wouter R.P.H. van deWorp +10 more
doaj +1 more source
Post-traumatic stress disorder (PTSD) is a severe, long-term psychological disorder triggered by distressing events. The neural basis and underlying mechanisms of PTSD are not completely understood.
Kaiwen Xi +9 more
doaj +1 more source
Awake chronic mouse model of targeted pial vessel occlusion via photothrombosis [PDF]
Animal models of stroke are used extensively to study the mechanisms involved in the acute and chronic phases of recovery following stroke. A translatable animal model that closely mimics the mechanisms of a human stroke is essential in understanding ...
Boas, David A. +9 more
core +1 more source
Seven-fluorochrome mouse M-FISH for high-resolution analysis of interchromosomal rearrangements [PDF]
The mouse has evolved to be the primary mammalian genetic model organism. Important applications include the modeling of human cancer and cloning experiments. In both settings, a detailed analysis of the mouse genome is essential.
Geigl, J. +3 more
core +1 more source
Olive polyphenol effects in a mouse model of chronic ethanol addiction [PDF]
Objectives Alcohol addiction elicits oxidative imbalance and it is well known that polyphenols possess antioxidant properties. We investigated whether or not polyphenols could confer a protective potential against alcohol-induced oxidative stress ...
Bello, Cristiano +7 more
core +1 more source

