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Mouse models of atherosclerosis
Current Opinion in Lipidology, 2001Atherosclerosis bears many features of a chronic inflammation that affects the intima of large and medium-sized arteries. In recent years apolipoprotein E-deficient and LDL receptor-deficient mice have been used to examine the effects of various gene products on the development of atherosclerosis.
C A, Reardon, G S, Getz
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The mouse model for atherosclerosis
Trends in Cardiovascular Medicine, 1993The mouse model provides unique tools for studies of the complex environmental and genetic interactions underlying atherosclerosis. In particular, a great variety of inbred strains exhibit variations affecting lipoprotein metabolism, diabetes, obesity, immune regulation, and other processes relevant to the disease.
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Journal of Genetics, 2009
Much of our knowledge about the function of genes in cataracts has been derived from the molecular analysis of spontaneous or induced mutations in the mouse. Mutations affecting the mouse lens can be identified easily by visual inspection, and a remarkable number of mutant lines have been characterized.
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Much of our knowledge about the function of genes in cataracts has been derived from the molecular analysis of spontaneous or induced mutations in the mouse. Mutations affecting the mouse lens can be identified easily by visual inspection, and a remarkable number of mutant lines have been characterized.
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A single-embryo, single-cell time-resolved model for mouse gastrulation
Cell, 2021Saifeng Cheng +2 more
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Mouse models of neurofibromatosis
Biochimica et Biophysica Acta (BBA) - Reviews on Cancer, 2001A I, McClatchey, K, Cichowski
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A Mouse Model of SARS-CoV-2 Infection and Pathogenesis
Cell Host and Microbe, 2020Guan Yang +2 more
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Novel mouse model reveals strategy to delay drug resistance in melanoma
Nature Reviews Clinical Oncology, 2013Hutchinson Lisa
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