Results 171 to 180 of about 29,777 (280)

Unveiling Endotypes in Systemic Lupus Erythematosus Through Multiomic Analysis: Insights Into Cardiovascular and Renal Complications

open access: yesArthritis &Rheumatology, Volume 78, Issue 10, Page 2124-2137, October 2026.
Objective Systemic lupus erythematosus (SLE) shows clinical and molecular heterogeneity, and cardiovascular (CV) complications and lupus nephritis (LN) remain leading causes of morbidity and mortality. This study investigated whether omic profiling can reveal molecular endotypes linked to these outcomes.
Tomás Cerdó   +84 more
wiley   +1 more source

Reduced platelet count in mice protects against glucose intolerance and beta cell loss during a long-term high-fat diet. [PDF]

open access: yesFront Immunol
Burkhard N   +10 more
europepmc   +1 more source

Extensive Cerebral Venous Sinus Thrombosis With Obstructive Hydrocephalus in a Young Female With Underlying Essential Thrombocythemia: A Case Report

open access: yesClinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT Persistent symptoms suggestive of idiopathic intracranial hypertension despite standard therapy should prompt urgent neuroimaging to exclude cerebral venous sinus thrombosis. When CVST is confirmed without an obvious provoking factor, evaluation for underlying myeloproliferative neoplasms, including JAK2‐positive essential thrombocythemia, is ...
Sarah Nafea   +6 more
wiley   +1 more source

MPL mutations are over-represented in patients with dual driver-mutated myeloproliferative neoplasms: an Irish cohort study. [PDF]

open access: yesHematol Transfus Cell Ther
Kearney L   +14 more
europepmc   +1 more source

Insights Into the Role of Platelet Factor 4 in Neurodegenerative Diseases

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 10, October 2026.
This review summarizes potential functions of platelet factor 4 (PF4) in neurodegenerative diseases (NDs) and discusses its promise as both a biomarker and a therapeutic target. Further elucidation of PF4 signaling pathways may provide new insights into disease mechanisms and uncover novel opportunities for targeted interventions in NDs.
Qi Tian   +3 more
wiley   +1 more source

Inflammatory and Immune Microenvironment in Myeloproliferative Neoplasms: Pathogenic Mechanisms and Therapeutic Opportunities. [PDF]

open access: yesCancers (Basel)
Kaikavoosnejad F   +9 more
europepmc   +1 more source

The thrombopoietin receptor S264F mutant drives MPN with marrow fibrosis through a dual mechanism [PDF]

open access: yesHemasphere
HemaSphere, Volume 10, Issue 10, October 2026.
Lees C   +9 more
europepmc   +2 more sources

Climate‐driven resource availability drives medium‐ and broad‐scale temporal changes in owl–prey interactions over 24 years in a semi‐arid ecosystem

open access: yesEcography, Volume 2026, Issue 10, October 2026.
Predator–prey interactions are vital to ecosystem functioning but may be disrupted by climate change. We investigated a food‐web network involving three owl species over 24 years in a semi‐arid ecosystem at Bosque Fray Jorge National Park, Chile.
Jazmin M. Quiroz‐Calizaya   +12 more
wiley   +1 more source

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