Dietary milk polar lipids ameliorate hepatic lipid accumulation through coordinated regulation of Wnt-PPARγ signaling and remodeling of the gut microbiota. [PDF]
Kim H, Park D, Kwon YJ, Imm JY.
europepmc +1 more source
Objective Systemic lupus erythematosus (SLE) shows clinical and molecular heterogeneity, and cardiovascular (CV) complications and lupus nephritis (LN) remain leading causes of morbidity and mortality. This study investigated whether omic profiling can reveal molecular endotypes linked to these outcomes.
Tomás Cerdó +84 more
wiley +1 more source
Reduced platelet count in mice protects against glucose intolerance and beta cell loss during a long-term high-fat diet. [PDF]
Burkhard N +10 more
europepmc +1 more source
Translational rehabilitation strategies for canine medial patellar luxation: insights from human patellofemoral pain syndrome. [PDF]
Son JY, Kim K, Seo YS, Yu SJ, Choi J.
europepmc +1 more source
ABSTRACT Persistent symptoms suggestive of idiopathic intracranial hypertension despite standard therapy should prompt urgent neuroimaging to exclude cerebral venous sinus thrombosis. When CVST is confirmed without an obvious provoking factor, evaluation for underlying myeloproliferative neoplasms, including JAK2‐positive essential thrombocythemia, is ...
Sarah Nafea +6 more
wiley +1 more source
MPL mutations are over-represented in patients with dual driver-mutated myeloproliferative neoplasms: an Irish cohort study. [PDF]
Kearney L +14 more
europepmc +1 more source
Insights Into the Role of Platelet Factor 4 in Neurodegenerative Diseases
This review summarizes potential functions of platelet factor 4 (PF4) in neurodegenerative diseases (NDs) and discusses its promise as both a biomarker and a therapeutic target. Further elucidation of PF4 signaling pathways may provide new insights into disease mechanisms and uncover novel opportunities for targeted interventions in NDs.
Qi Tian +3 more
wiley +1 more source
Inflammatory and Immune Microenvironment in Myeloproliferative Neoplasms: Pathogenic Mechanisms and Therapeutic Opportunities. [PDF]
Kaikavoosnejad F +9 more
europepmc +1 more source
The thrombopoietin receptor S264F mutant drives MPN with marrow fibrosis through a dual mechanism [PDF]
HemaSphere, Volume 10, Issue 10, October 2026.
Lees C +9 more
europepmc +2 more sources
Predator–prey interactions are vital to ecosystem functioning but may be disrupted by climate change. We investigated a food‐web network involving three owl species over 24 years in a semi‐arid ecosystem at Bosque Fray Jorge National Park, Chile.
Jazmin M. Quiroz‐Calizaya +12 more
wiley +1 more source

