Results 61 to 70 of about 312 (110)

Overexpression of melanocortin 2 receptor accessory protein 2 (MRAP2) in adult paraventricular MC4R neurons regulates energy intake and expenditure [PDF]

, 2018
The Medical Research Council UK (MRC/Academy of Medical Sciences Clinician Scientist Fellowship Grant G0802796 (to LFC) and NIH grants R01 DK105571, DK097566 and DK107293 (to SD)
Bruschetta, G, Chan, LF, Diano, S, Kim, JD   +3 more
core   +1 more source

Corrigendum to “Pharmacological properties of whale shark (Rhincodon typus) melanocortin-2 receptor and melancortin-5 receptor: Interaction with MRAP1 and MRAP2” [Gen. Comp. Endocrinol. 293 (2020) 113463]

General and Comparative Endocrinology, 2022
Brianne E. Hoglin, Marin Miner, Robert M. Dores   +2 more
openaire   +1 more source

Calcium-Driven In Silico Inactivation of a Human Olfactory Receptor [PDF]

Conformational changes as well as molecular determinants related to the activation and inactivation of olfactory receptors are still poorly understood due to the intrinsic difficulties in the structural determination of this GPCR family. Here, we perform,
Alfonso-Prieto, Mercedes, Ballabio, Federico, Capelli, Riccardo, Pirona, Lorenza   +3 more
core   +1 more source

Further Insight into the Two Functions of Telomeres: Determining the Role of Tankyrase1 in Telomere Length Regulation and Tin2 in Telomere Protection [PDF]

, 2008
Tankyrase1 is a multifunctional poly(ADP-ribose) polymerase that can localize to telomeres through its interaction with the shelterin component TRF1. Tankyrase1 poly(ADP-ribosyl)ates TRF1 in vitro, and its nuclear overexpression leads to loss of TRF1 and
Donigian, Jill
core   +1 more source

Melanocortin-4 Receptor PLC Activation Is Modulated by an Interaction with the Monocarboxylate Transporter 8 [PDF]

The melanocortin-4 receptor (MC4R) is a key player in the hypothalamic leptin-melanocortin pathway that regulates satiety and hunger. MC4R belongs to the G protein-coupled receptors (GPCRs), which are known to form heterodimers with other membrane ...
Anthofer, Larissa, Bechmann, Ingo, Beck-Sickinger, Annette G., Biebermann, Heike, Gmach, Philipp, Kleinau, Gunnar, Krude, Heiko, Kühnen, Peter, Opitz, Robert, Paisdzior, Sarah, Rotter, Jonas, Scheerer, Patrick, Uretmen Kagiali, Zeynep Cansu, Wolf, Philipp   +13 more
core   +1 more source

Determination of the Interaction and Pharmacological Modulation of MCHR1 Signaling by the C-Terminus of MRAP2 Protein. [PDF]

Front Endocrinol (Lausanne), 2022
Wang M, Zhai Y, Lei X, Xu J, Jiang B, Kuang Z, Zhang C, Liu S, Bian S, Yang XM, Zan T, Jin LN, Li Q, Zhang C.   +13 more
europepmc   +1 more source

Editorial: Glucosensing impact on glucose metabolism: From fish to mammals. [PDF]

Front Endocrinol (Lausanne), 2022
Yuan XC, Tao YX.
europepmc   +1 more source

MRAP2 regulates energy homeostasis by promoting primary cilia localization of MC4R. [PDF]

JCI Insight, 2023
Bernard A, Ojeda Naharros I, Yue X, Mifsud F, Blake A, Bourgain-Guglielmetti F, Ciprin J, Zhang S, McDaid E, Kim K, Nachury MV, Reiter JF, Vaisse C.   +12 more
europepmc   +1 more source

Editorial: Neuropeptide GPCRs in neuroendocrinology, Volume II. [PDF]

Front Endocrinol (Lausanne), 2023
Vaudry H, Schoofs L, Civelli O, Kojima M.   +3 more
europepmc   +1 more source

Melanocortin-5 Receptor: Pharmacology and Its Regulation of Energy Metabolism. [PDF]

Int J Mol Sci, 2022
Ji LQ, Hong Y, Tao YX.
europepmc   +1 more source