Characterization of the Whale Shark (Rhincodon Typus) Melanocortin-2 Receptor [PDF]
Among bony vertebrates, the melanocortin-2 receptor ortholog is unique among the family of five melanocortin receptors on the basis that it is dependent on its accessory protein, MRAP1, for trafficking and activation, and is selective for activation by ...
Hoglin, Brianne
core +1 more source
Advances in comparative endocrinology : vol. VIII [PDF]
Ponències presentades al 10th Congress of the Iberian Association of Comparative Endocrinology (AIEC), celebrat a la Universitat Jaume I, els dies 23 al 25 de setembre de 2015Les diverses comunicacions presentades al 10è Congrés de la Asociación Ibérica ...
Calduch-Giner, Josep +2 more
core +1 more source
Evolution of Xenopus Tropicalis MC2R: Expression and Activation [PDF]
The structure and functional relationship between the melanocortin-2 receptor (MC2R) and adrenocorticotropic hormone (ACTH) is the most complex of the melanocortin gene family.
Davis, Perry Victoria
core +1 more source
Keeping Balance Between Genetic Stability and Plasticity at the Telomere and Subtelomere of Trypanosoma brucei [PDF]
Telomeres, the nucleoprotein complexes at chromosome ends, are well-known for their essential roles in genome integrity and chromosome stability. Yet, telomeres and subtelomeres are frequently less stable than chromosome internal regions.
Li, Bibo, Ph.D.
core +2 more sources
Pharmacological modulation of MRAP2 protein on melanocortin receptors in the sea lamprey [PDF]
Melanocortin receptors (MCRs) and their accessory proteins (MRA Ps) evolutionarily first appear in the genome of sea lamprey. The most ancient melanocortin system consists of only two melanocortin receptors (slMCa and slMCb) and one MRAP2 (slMRAP2 ...
Bingxin Xu +5 more
core +1 more source
Impact of insulin sensitising interventions on women with polycystic ovary syndrome and healthy humans [PDF]
Polycystic ovary syndrome (PCOS) is the most common endocrinology condition in premenopausal women, with a prevalence of 8%-12% in this population. The presentation can vary between individuals, and although obesity is not part of the current diagnostic ...
Samarasinghe, Suhaniya
core +1 more source
Effect of age and pregnancy on the murine melanocortin system in the female reproductive system [PDF]
The five melanocortin receptors (MC (1-5)) are part of the G-coupled protein receptor (GPCR) family and have been reported to have a role in controlling appetite, modulating inflammation and stress response.
Berruien, N., Berruien, N.
core
DU Undergraduate Showcase: Research, Scholarship, and Creative Works: Abstracts [PDF]
s from the DU Undergraduate ...
Aggeler, Emma +58 more
core +1 more source
Functional Activation of Cartilaginous Fish Melanocortin Receptors [PDF]
The evolution of the melanocortin receptor (MCR) gene family has been dictated by two genome duplication events (2R hypothesis). The gnathostomes are thus predicted to possess a minimum of four MCR genes. Previous studies on cartilaginous fish have shown
Reinick, Christina Lee
core +1 more source
Emerging roles of melanocortin receptor accessory proteins (MRAP and MRAP2) in physiology and pathophysiology. [PDF]
Melanocortin-2 receptor accessory protein (MRAP) has an unusual dual topology and influences the expression, localisation, signalling and internalisation of the melanocortin receptor 2 (MC ); the adrenocorticotropic hormone (ACTH) receptor.
Adan +65 more
core +1 more source

