Results 121 to 130 of about 19,153 (149)

Comparison of wasting syndrome in [MRL lprlpr-MRL+/+] chimera and graft versus host disease in [B10.D2-BALBc] chimera and an attempt to transfer the wasting syndrome in [MRL lprlpr-MRL+/+] chimera to MRL+/+ mice

Journal of Dermatological Science, 1993
Abstract We compared the findings in the wasting syndrome seen in [ MRL lpr lpr → MRL +/+ ] chimeras with those of chronic graft versus host disease (GVHD) in [ B10.D2 → BALB c ] chimeras. BALB c mice were lethally irradiated and administered B10.D2 spleen and bone marrow cells.
Michiko Aihara, Hiroshi Nakajima
openaire   +1 more source

FURTHER SEROLOGICAL AND RFLP ANALYSIS OF THE MRL‐+/+ AND MRL‐lpr/lpr MICE

International Journal of Immunogenetics, 1988
SUMMARYDuring their ageing, MRL‐lpr/lpr mice (H‐2k) suffer from progressive lymph node enlargement, associated with the development of several acute autoimmune lesions. The primary effect and location of the lpr mutation is unknown. However, a minority of the lymphoid cells of some MRL‐ +/+, as well as MRL‐lpr/lpr mice, express ‘alien’ H‐2d antigenic ...
C, Delarbre, P, Bobe, N, Kiger, P, Kourilsky, G, Gachelin   +4 more
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Band keratopathy in MRL/l and MRL/n mice.

Arthritis and rheumatism, 1983
To define ocular abnormalities in mice with autoimmune disease, we performed biomicroscopic examinations and examined ocular tissue in MRL/l, MRL/n, NZB, NZB/NZW, and Palmerston North mice. Results were compared with MRL/Mp--lpr/lpr, C57BL/6J--lpr/lpr, and normal control strains. Eighty-seven percent of MRL/l and MRL/n mice had typical band keratopathy;
Hoffman, R W, Yang, H K, Waggie, K S, Durham, J B, Burge, J R, Walker, S E   +5 more
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Previous Examinations of MRLs

2017
A review of the literature on MRLs and their effect on international trade is presented. The literature is far from extensive but, in general, confirms the propositions regarding the effects of asynchronous regulatory regimes among countries. Reduced international trade levels are reported.
May T. Yeung, William A. Kerr, Blair Coomber, Matthew Lantz, Alyse McConnell   +4 more
openaire   +1 more source

Immune response, tolerance circumvention and autoantibodies in aging MRL/MP-lpr and MRL/MP-+ MICE

Molecular Immunology, 1985
Isotype distribution was analyzed, as a function of age in MRL/Mp-lpr and MRL/Mp-+ mice. The mice were tested for: (1) "spontaneous" response to nucleic acid (2) induced response to alum-precipitated phosphorylcholine-rabbit gamma globulin (PC-RGG) (immunized animals) and (3) induced response to alum-precipitated PC-RGG after pretreatment with ...
U, Ponnappan, A, Kohno, V, Gerber, K, Blaser, B, Cinader   +4 more
openaire   +2 more sources

Early days at MRL

British Ceramic Transactions, 2004
AbstractFor the past 40 years, Eric Cross has been the worldwide leader of the international ferroelectrics community, organising meetings, advising students and colleagues, and building up an outstanding research programme at Penn State University.
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Induction of Ovulation with MRL/41

JAMA, 1961
MRL/41, an analogue of the nonsteroid estrogen, chlorotrianisene, was evaluated in the human female because it was shown to possess pituitary gonadotropin-inhibiting and antifecundity properties in rats. Although structurally related to a hormone-like chemical agent, this compound does not exhibit estrogenic, progestogenic, or androgenic activity in ...
R B, GREENBLATT, W E, BARFIELD, E C, JUNGCK, A W, RAY   +3 more
openaire   +2 more sources

Antibody Feedback Regulation in MRL/lpr Mice

Journal of Autoimmunity, 1993
MRL/Mp-lpr/lpr (MRL/l) mice spontaneously develop autoimmune disease, characterized by glomerulonephritis, polyarteritis and polyarthritis. The lpr mice have defects in the Fas antigen, which plays a role in apoptosis, and it has been suggested that lack of negative selection of autoreactive T cells explains the initiation of the disease. The extremely
B, Heyman, S, Gustavsson, C, Kusakari, M, Nose, T, Kinoshita, L, Klareskog, A, Tarkowski   +6 more
openaire   +2 more sources

Comparison of wasting syndrome in [MRL lpr/lpr-->MRL +/+] chimera and graft versus host disease in [B10.D2-->BALB/c] chimera and an attempt to transfer the wasting syndrome in [MRL lpr/lpr-->MRL +/+] to MRL +/+ mice.

Journal of dermatological science, 1994
We compared the findings in the wasting syndrome seen in [MRL lpr/lpr--> MRL +/+] chimeras with those of chronic graft versus host disease (GVHD) in [B10.D2-->BALB/c] chimeras. BALB/c mice were lethally irradiated and administered B10.D2 spleen and bone marrow cells. These mice are identical to MHC and Mls but differ as to genetic background.
M, Aihara, Y, Aihara, H, Nakajima
openaire   +1 more source

Japan MRL Regulation

2008
Takagi, Chifumi, Thornsbury, Suzanne, Takagi, Chifumi, Thornsbury, Suzanne   +3 more
openaire   +3 more sources