Results 301 to 310 of about 2,706,783 (351)
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Current Opinion in Cell Biology, 2001
Nuclear RNA-binding proteins can record pre-mRNA processing events in the structure of messenger ribonucleoprotein particles (mRNPs). During initial rounds of translation, the mature mRNP structure is established and is monitored by mRNA surveillance systems. Competition for the cap structure links translation and subsequent mRNA degradation, which may
P, Mitchell, D, Tollervey
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Nuclear RNA-binding proteins can record pre-mRNA processing events in the structure of messenger ribonucleoprotein particles (mRNPs). During initial rounds of translation, the mature mRNP structure is established and is monitored by mRNA surveillance systems. Competition for the cap structure links translation and subsequent mRNA degradation, which may
P, Mitchell, D, Tollervey
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RIBONUCLEOPROTEIN PARTICLES CONTAINING mRNA and pre-mRNA
Acta Endocrinologica, 1973ABSTRACT This paper is a review of the data concerning the nature, structural organization, properties and biological significance of the particles, containing mRNA and pre-mRNA (precursor of mRNA), i. e., (1) nuclear pre-mRNA-containing particles (2) free cytoplasmic mRNP (ribonucleoproteins), or informosomes (3) polysome-bound mRNP.
O P, Samarina +2 more
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Pre-mRNA processing and mRNA nuclear export
Current Opinion in Cell Biology, 1989The primary transcript of a prokaryotic gene is translated immediately following or during synthesis, whereas in eukaryotes, messenger RNA (mRNA) precursors (premRNAs) are synthesized in the nucleus and are then structurally altered and relocated to the cytoplasm before translation (Fig. 1).
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Annual Review of Biochemistry, 2004
▪ Abstract Eukaryotic mRNAs are primarily degraded by removal of the 3′ poly(A) tail, followed either by cleavage of the 5′ cap structure (decapping) and 5′->3′ exonucleolytic digestion, or by 3′ to 5′ degradation. mRNA decapping represents a critical step in turnover because this permits the degradation of the mRNA and is a site of numerous ...
Jeff, Coller, Roy, Parker
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▪ Abstract Eukaryotic mRNAs are primarily degraded by removal of the 3′ poly(A) tail, followed either by cleavage of the 5′ cap structure (decapping) and 5′->3′ exonucleolytic digestion, or by 3′ to 5′ degradation. mRNA decapping represents a critical step in turnover because this permits the degradation of the mRNA and is a site of numerous ...
Jeff, Coller, Roy, Parker
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Current Protocols in Cell Biology, 2008
AbstractTransport of mRNA from the nucleus to the cytoplasm is an essential process for gene expression in eukaryotic cells. In this unit, methods for monitoring nuclear mRNA export are described. Visualization of cellular mRNAs by fluorescence in situ hybridization with oligo(dT) probes is effectively applied to monitoring mRNA export from the nucleus
Kazuaki, Tokunaga, Tokio, Tani
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AbstractTransport of mRNA from the nucleus to the cytoplasm is an essential process for gene expression in eukaryotic cells. In this unit, methods for monitoring nuclear mRNA export are described. Visualization of cellular mRNAs by fluorescence in situ hybridization with oligo(dT) probes is effectively applied to monitoring mRNA export from the nucleus
Kazuaki, Tokunaga, Tokio, Tani
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Current Opinion in Cell Biology, 2003
Recent studies demonstrate that the factors involved in mRNA processing specify the fate of a transcript. The mRNA is either committed for export to the cytoplasm or accumulates in the nucleus, where it may be degraded. These studies reveal crosstalk among the nuclear events faced by the pre-mRNA.
Shobha, Vasudevan, Stuart W, Peltz
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Recent studies demonstrate that the factors involved in mRNA processing specify the fate of a transcript. The mRNA is either committed for export to the cytoplasm or accumulates in the nucleus, where it may be degraded. These studies reveal crosstalk among the nuclear events faced by the pre-mRNA.
Shobha, Vasudevan, Stuart W, Peltz
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Current Opinion in Genetics & Development, 1994
The export of mRNA from the nucleus to the cytoplasm is an essential step in the expression of genetic information in eukaryotes. It is an energy-dependent process and involves transport across the nuclear pores. It requires both cis-acting ribonucleoprotein particle signals and specific trans-acting factors. Although much remains to be learned, recent
D J, Elliott +3 more
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The export of mRNA from the nucleus to the cytoplasm is an essential step in the expression of genetic information in eukaryotes. It is an energy-dependent process and involves transport across the nuclear pores. It requires both cis-acting ribonucleoprotein particle signals and specific trans-acting factors. Although much remains to be learned, recent
D J, Elliott +3 more
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