Results 311 to 320 of about 2,706,783 (351)
Some of the next articles are maybe not open access.
2016
mRNA cancer vaccines are a relatively new class of vaccines, which combine the potential of mRNA to encode for almost any protein with an excellent safety profile and a flexible production process. The most straightforward use of mRNA vaccines in oncologic settings is the immunization of patients with mRNA vaccines encoding tumor-associated antigens ...
Katja, Fiedler +4 more
openaire +2 more sources
mRNA cancer vaccines are a relatively new class of vaccines, which combine the potential of mRNA to encode for almost any protein with an excellent safety profile and a flexible production process. The most straightforward use of mRNA vaccines in oncologic settings is the immunization of patients with mRNA vaccines encoding tumor-associated antigens ...
Katja, Fiedler +4 more
openaire +2 more sources
Current Opinion in Genetics & Development, 1994
Information from yeast and mammalian pre-mRNA splicing systems has advanced our understanding of the roles of protein factors in the early steps of spliceosome assembly. New results on the stereochemistry of nuclear pre-mRNA splicing and data on the transposition of Group II self-splicing introns in vivo have fuelled the long-running debate on the ...
openaire +2 more sources
Information from yeast and mammalian pre-mRNA splicing systems has advanced our understanding of the roles of protein factors in the early steps of spliceosome assembly. New results on the stereochemistry of nuclear pre-mRNA splicing and data on the transposition of Group II self-splicing introns in vivo have fuelled the long-running debate on the ...
openaire +2 more sources
Current Opinion in Cell Biology, 1991
Nuclear mRNA export through the nuclear pore complex has been proposed to be a unidirectional, signal-mediated and energy-dependent process. Evidence exists that this process can be influenced by many factors including other steps in the pathway of cytoplasmic mRNA formation, sequences of the RNA substrate that are either transcribed or added co- or ...
openaire +2 more sources
Nuclear mRNA export through the nuclear pore complex has been proposed to be a unidirectional, signal-mediated and energy-dependent process. Evidence exists that this process can be influenced by many factors including other steps in the pathway of cytoplasmic mRNA formation, sequences of the RNA substrate that are either transcribed or added co- or ...
openaire +2 more sources
Nucleocytoplasmic mRNA Transport
2001How do messenger RNA molecules (mRNAs) migrate from the nucleus to the cytoplasm? Messenger RNA precursors (pre-mRNAs) are synthesized in the nucleus by RNA polymerase II and are then subjected to a series of processing reactions which include the addition of a 7-methylguanosine cap at the 5’ end, the removal of introns by splicing, and the generation ...
Y, Huang, G G, Carmichael
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Targeting cancer with mRNA–lipid nanoparticles: key considerations and future prospects
Nature Reviews Clinical Oncology, 2023, Dan Peer
exaly
mRNA vaccines for infectious diseases: principles, delivery and clinical translation
Nature Reviews Drug Discovery, 2021Namit Chaudhary, Kathryn A Whitehead
exaly