Results 11 to 20 of about 881,660 (270)
mRNA export: threading the needle [PDF]
After mRNA biogenesis, several proteins interact with the messenger to ensure its proper export to the cytoplasm. Some of these proteins will bind RNA early on, at the onset of transcription by RNA polymerase II holoenzyme, while others will join later ...
Hugo eGermain, Ouassila eGaouar
doaj +6 more sources
Nuclear mRNA Export and Aging. [PDF]
The relationship between transcription and aging is one that has been studied intensively and experimentally with diverse attempts. However, the impact of the nuclear mRNA export on the aging process following its transcription is still poorly understood,
Park HS, Lee J, Lee HS, Ahn SH, Ryu HY.
europepmc +4 more sources
Export of mRNA through nuclear pore complexes (NPC) is preceded by multiple and well coordinated processing steps, resulting in the formation of an export competent ribonucleoprotein complex (mRNP).
Daniel Zenklusen +4 more
core +6 more sources
Nuclear roadblocks for mRNA export. [PDF]
The THO complex and Sub2 RNA helicase have been shown to function in both transcription and mRNA processing. Rougemaille et al.
Ana G. Rondon +6 more
core +4 more sources
Multiple Export Mechanisms for mRNAs [PDF]
Nuclear mRNA export plays an important role in gene expression. We describe the mechanisms of mRNA export including the importance of mRNP assembly, docking with the nuclear basket of the nuclear pore complex (NPC), transit through the central channel of
Mildred Delaleau, Katherine L. B. Borden
doaj +4 more sources
The Ccr4-Not complex interacts with the mRNA export machinery. [PDF]
The Ccr4-Not complex is a key eukaryotic regulator of gene transcription and cytoplasmic mRNA degradation. Whether this complex also affects aspects of post-transcriptional gene regulation, such as mRNA export, remains largely unexplored.
Shana C Kerr +6 more
doaj +7 more sources
A Conserved mRNA Export Machinery Coupled to pre-mRNA Splicing [PDF]
Recent advances have led to a new understanding of how mRNAs are exported from the nucleus to the cytoplasm. This process requires a heterodimeric mRNA export receptor that is part of an elaborate machinery conserved from yeast to humans. Export of mRNAs
Reed, Robin, Hurt, Ed
core +4 more sources
SRAG Functions as a New mRNA Export Co-adaptor [PDF]
DEAD box RNA helicases play important roles in many cellular processes including splicing, mRNA export and translation. The two domains of many DEAD box RNA helicases adopt radically different conformations according to whether they are ...
Chang, Chung-Te
core +6 more sources
This PhD focuses on the relationship between mRNA export and ...
Cumberbatch, Marcus G
core +6 more sources
Nuclear mRNA maturation and mRNA export control: from trypanosomes to opisthokonts. [PDF]
The passage of mRNAs through the nuclear pores into the cytoplasm is essential in all eukaryotes. For regulation, mRNA export is tightly connected to the full machinery of nuclear mRNA processing, starting at transcription. Export competence of pre-mRNAs
Kramer S.
europepmc +2 more sources

