Results 1 to 10 of about 2,221,278 (207)
CD69 is a TGF-β/1α,25-dihydroxyvitamin D3 target gene in monocytes [PDF]
, 2013 CD69 is a transmembrane lectin that can be expressed on most hematopoietic cells. In monocytes, it has been functionally linked to the 5-lipoxygenase pathway in which the leukotrienes, a class of highly potent inflammatory mediators, are produced ...
A Diaz +52 more
core +20 more sources
Expression of inflammation-related genes is associated with adipose tissue location in horses [PDF]
, 2013 Background : In humans, adipose tissue (AT) originating from different depots shows varying gene expression profiles. In horses, the risk of certain metabolic disorders may also be influenced by the impact of specific AT depots.
Bruynsteen, Lien +6 more
core +10 more sources
GLUTAMINE DEPRIVATION AFFECTS THE EXPRESSION OF GENES WHICH CONTROL PYRUVATE DEHYDROGENASE ACTIVITY: THE IMPACT OF ERN1 KNOCKDOWN [PDF]
Biotechnologia Acta, 2022 The aim of the current investigation was to study the expression of genes encoded pyruvate dehydrogenase subunits (PDHA1, PDHB, PDHX, DLAT, and DLD) in U87 glioma cells in response to glutamine deprivation in U87 glioma cells in relation to knockdown of ...
M. Sliusar +3 more
doaj +1 more source
Hypoxic regulation of mRNA expression [PDF]
Cell Cycle, 2008 Many tumors are hypoxic, and cells that are experimentally rendered hypoxic display a variety of phenotypes which allow them to adapt to the micro-environment. These phenotypes include a shift from aerobic to anaerobic metabolism, a diminution of reactive oxygen species, an arrest of proliferation, apoptosis, and a secretion of pro-angiogenic growth ...
Lawrence B, Gardner, Paul G, Corn
openaire +2 more sources
Endocrine Regulations, 2022 Objective. The aim of the current study was to investigate the expression of genes encoded homeobox proteins such as MEIS3 (Meis homeobox 3), SPAG4 (sperm associated antigen 4), LHX1 (LIM homeobox 1), LHX2, and LHX6 in U87 glioma cells in response to ...
Krasnytska Dariia A. +7 more
doaj +1 more source
HuR mRNA Ligands Expressed After Seizure [PDF]
Journal of Neuropathology and Experimental Neurology, 2005 HuR is a ubiquitously expressed AU-rich element (ARE)-binding protein that interacts with and stabilizes selective early response gene (ERG) mRNAs after cell activation or stress. To date, approximately 20 mRNAs have been unambiguously defined as HuR ligands.
Cara J, Westmark +6 more
openaire +2 more sources
Reference genes for measuring mRNA expression [PDF]
Theory in Biosciences, 2012 The aim of this review is to find answers to some of the questions surrounding reference genes and their reliability for quantitative experiments. Reference genes are assumed to be at a constant expression level, over a range of conditions such as temperature.
Dundas, J, Ling, M
openaire +3 more sources
OncoImmunology, 2021 Immune checkpoint blockade (ICB) expands the therapeutic options for metastatic lung cancer nowadays representing a standard frontline strategy as monotherapy or combination therapy, as well as an option in oncogene-addicted NSCLC after exhaustion of ...
Jan Budczies +18 more
doaj +1 more source
Effect of all-trans retinoic acid on casein and fatty acid synthesis in MAC-T cells [PDF]
Asian-Australasian Journal of Animal Sciences, 2020 Objective Caseins and fatty acids of milk are synthesized and secreted by the epithelial cells of the mammary gland. All-trans retinoic acid (ATRA), an active metabolite of vitamin A, has been shown to promote mammary development.
Xian-Dong Liao +6 more
doaj +1 more source
High MYC mRNA expression is more clinically relevant than MYC DNA amplification in triple-negative breast cancer [PDF]
, 2019 DNA abnormalities are used in inclusion criteria of clinical trials for treatments with specific targeted molecules. MYC is one of the most powerful oncogenes and is known to be associated with triple-negative breast cancer (TNBC).
Dasgupta, Subhamoy +6 more
core +2 more sources