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CD27 mRNA expression in mycosis fungoides

Italian Journal of Dermatology and Venereology, 2022
The etiopathogenesis of MF remains obscure. CD27 is a member of the tumor necrosis factor receptor superfamily (TNFRS) that regulates lymphocyte function. Expression of CD27 protein and mRNA has been reported in B-cell lymphomas and adult T-cell leukemia/lymphoma. In this study, we examined the expression of CD27 in the skin of MF patients by real time
Galliano, Ilaria   +6 more
openaire   +3 more sources

Cloning differentially expressed mRNAs

Nature Biotechnology, 1996
Differential gene expression occurs in the process of development, maintenance, injury, and death of unicellular as well as complex organisms. Differentially expressed genes are usually identified by comparing steady-state mRNA concentrations. Electronic subtraction (ES), subtractive hybridization (SH), and differential display (DD) are methods ...
J S, Wan   +11 more
openaire   +2 more sources

FHIT mRNA expression in thymoma

European Journal of Surgical Oncology (EJSO), 2003
The FHIT gene is located at 3p14.2 a region frequently lost in multiple tumour types. Loss of FHIT expression has been found to occur frequently in multiple tumour types. We wished to investigate that FHIT mRNA levels in a series of thymomas.Expression of FHIT messenger ribonucleic acid (RNA) was evaluated by reverse transcription-polymerase chain ...
H, Sasaki   +5 more
openaire   +2 more sources

TNF-α mRNA Expression Correlates with TGF-β mRNA Expression In Vivo

Inflammation, 2010
TNF-α is postulated to play a significant role in regulating TGF-β(1) expression. In lung fibroblasts, for example, TNF-α is supposed to induce TGF-β(1) via AP-1 activation. TNF-α receptor, knock-out mice are resistant to induced fibrosis and over-expression of TNF-α causes increased TGF-β(1) production in mice. Therefore, we investigated whether TNF-α
Simone, Helmig   +3 more
openaire   +2 more sources

Endothelial Cell Expression of Testican mRNA

Endothelium, 1997
By screening random cDNAs from a continuous vascular endothelial cell line, EA.hy926, we identified a 5 kb mRNA that is expressed at high levels by this human cell line and by an early passage umbilical vein endothelial cell line. It is detected at lower levels in certain stromal cell lines, but it is not detected in most other cell lines tested ...
H S, Marr, M A, Basalamah, C J, Edgell
openaire   +2 more sources

Developmental expression of cannabinoid receptor mRNA

Developmental Brain Research, 1993
Cloning of the cannabinoid receptor affords the opportunity to examine its developmental expression. Other G-protein-coupled receptor systems, those for the opioids for example, exhibit distinct ontogenies. For the initial study, therefore, cannabinoid receptor mRNA expression was assessed in rat pups postnatal days 3, 5, 8, 10, 12, 15, 18 and 21.
C R, McLaughlin, M E, Abood
openaire   +2 more sources

Unsupervised clustering in mRNA expression profiles

Computers in Biology and Medicine, 2006
The development of microarray technologies gives scientists the ability to examine, discover and monitor the mRNA transcript levels of thousands of genes in a single experiment. Nonetheless, the tremendous amount of data that can be obtained from microarray studies presents a challenge for data analysis.
D K, Tasoulis   +2 more
openaire   +2 more sources

Patterns of cerebral cortex mRNA expression

Journal of Neuroscience Research, 1990
AbstractA pool of 163 clones, isolated by screening 60,000 members of a Macaca fascicularis cerebral cortex cDNA library with a cortex‐minus‐cerebellum subtracted probe prepared by the phenol enhancement method, was analyzed by Northern blot hybridization studies.
J, Bernal   +4 more
openaire   +2 more sources

Increased IL-10 mRNA and IL-23 mRNA expression in multiple sclerosis: interferon-β treatment increases IL-10 mRNA expression while reducing IL-23 mRNA expression

Multiple Sclerosis Journal, 2008
Background Interferon (IFN)-β therapy in multiple sclerosis (MS) has been suggested to promote a deviation from T lymphocyte production of pathogenic Th1 cytokines to less detrimental Th2 cytokines, but this is still controversial. We studied patterns of in vivo blood mononuclear cell (MNC) and whole blood cytokine and transcription factor mRNA ...
Krakauer, M.   +4 more
openaire   +2 more sources

Reelin mRNA Expression During Mouse Brain Development

European Journal of Neuroscience, 1997
AbstractUsing in situ hybridization, expression of the mRNA for reelin, the gene most probably responsible for the reeler trait, was studied during mouse brain development. from embryonic day 13 to maturity. The highest level of expression was found in Cajal‐Retzius neurons, while a high signal was also seen in the olfactory bulb, the external granular
Schiffmann, Serge N.   +2 more
openaire   +3 more sources

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