Results 251 to 260 of about 602,475 (301)
Citrullinated IGF2BP1 promotes rheumatoid synovial aggression via increasing the mRNA stability of SEMA3D. [PDF]
Commun BiolQin Y +7 more
europepmc +1 more source
Correction to 'RNPC1 modulates the RNA-binding activity of, and cooperates with, HuR to regulate p21 mRNA stability'. [PDF]
Nucleic Acids Reseuropepmc +1 more source
The Legionella pneumophila effector PieF modulates mRNA stability through association with eukaryotic CCR4-NOT. [PDF]
mSphereMount HO +4 more
europepmc +1 more source
Some of the next articles are maybe not open access.
Related searches:
Related searches:
Current Opinion in Genetics & Development, 2000
During the past two years, the role of the proteins HuR and hnRNP D in regulated mRNA degradation in humans has become clearer, and a putative mRNA deadenylase, DAN or PARN, has been identified. In yeast, the relationship between translation and mRNA turnover is clearer, but the mRNA decapping process has turned out to be unexpectedly complex.
P, Mitchell, D, Tollervey
openaire +2 more sources
During the past two years, the role of the proteins HuR and hnRNP D in regulated mRNA degradation in humans has become clearer, and a putative mRNA deadenylase, DAN or PARN, has been identified. In yeast, the relationship between translation and mRNA turnover is clearer, but the mRNA decapping process has turned out to be unexpectedly complex.
P, Mitchell, D, Tollervey
openaire +2 more sources
Cellular and Molecular Life Sciences, 2001
An important mechanism of posttranscriptional gene regulation in mammalian cells is the rapid degradation of messenger RNAs (mRNAs) signaled by AU-rich elements (AREs) in their 3' untranslated regions. HuR, a ubiquitously expressed member of the Hu family of RNA-binding proteins related to Drosophila ELAV, selectively binds AREs and stabilizes ARE ...
C M, Brennan, J A, Steitz
openaire +2 more sources
An important mechanism of posttranscriptional gene regulation in mammalian cells is the rapid degradation of messenger RNAs (mRNAs) signaled by AU-rich elements (AREs) in their 3' untranslated regions. HuR, a ubiquitously expressed member of the Hu family of RNA-binding proteins related to Drosophila ELAV, selectively binds AREs and stabilizes ARE ...
C M, Brennan, J A, Steitz
openaire +2 more sources
Current Opinion in Cell Biology, 1992
The regulation of mRNA stability is an important step in the control of gene expression. Characterization of the mechanisms involved in the turnover of individual mRNAs has identified a requirement for specific cis-acting sequences and trans-acting factors, as well as an involvement of the translation apparatus.
S W, Peltz, A, Jacobson
openaire +2 more sources
The regulation of mRNA stability is an important step in the control of gene expression. Characterization of the mechanisms involved in the turnover of individual mRNAs has identified a requirement for specific cis-acting sequences and trans-acting factors, as well as an involvement of the translation apparatus.
S W, Peltz, A, Jacobson
openaire +2 more sources
Translation affects immunoglobulin mRNA stability
European Journal of Immunology, 1989AbstractWhen termination codons were introduced into exons of the gene for Ig m̈ chain, steady‐state levels of m̈ mRNA were reduced, both at the pre‐B cell stage and at the plasma cell stage. A termination codon in the variable region gene segment and a termination codon in the second exon of the constant region gene segment had effects of similar ...
H M, Jäck, J, Berg, M, Wabl
openaire +2 more sources
Connections Underlying Translation and mRNA Stability
Journal of Molecular Biology, 2016Gene expression and regulation in organisms minimally depends on transcription by RNA polymerase and on the stability of the RNA product (for both coding and non-coding RNAs). For coding RNAs, gene expression is further influenced by the amount of translation by the ribosome and by the stability of the protein product.
Aditya, Radhakrishnan, Rachel, Green
openaire +2 more sources
Regulation of proto-oncogene mRNA stability
Biochimica et Biophysica Acta (BBA) - Reviews on Cancer, 1992IV. Mechanisms of degradation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . A. Deadenylation precedes decay . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . B. Translational coupling . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
S C, Schiavi +2 more
openaire +2 more sources
Stability and degradation of mRNA
Current Opinion in Cell Biology, 1991Differential mRNA stability plays an important role in the regulation of gene expression. Several recent advances have helped to define the general pathways by which mRNA is degraded in prokaryotic cells, although many details remain to be elucidated.
openaire +2 more sources