Results 101 to 110 of about 203,318 (355)

P27: DELAYED‐ONSET ANAPHYLAXIS TO AN MRNA COVID‐19 VACCINE IN A PAEDIATRIC PATIENT [PDF]

, 2023
David Thai, M. Gold, Abigail Cheung, D Cheng, K Perrett, S Choo, M Danchin, J Buttery, N Crawford, H Maltezou, S Hatziantoniou, K Theodoridou, K Vasileiou, C Anastassopoulou, A Tsakris, M Gold, A Amarasinghe, M Greenhawt, J Kelso, S Kochhar, By-H Thong, T Shimabukuro, M Cole, J Su, A Cheung, S Choo, K Perrett, S Limb, P Starke, C Lee, B Chowdhury, M Pitlick, A Sitek, D' Netto, M Dages, K Chiarella, S Gonzalez-Estrada, A Joshi, A   +38 more
openalex   +1 more source

Small Extracellular Vesicles‐Derived Circ6718 Unlocks Stromal Remodeling and Serves as a Biomarker in Gastric Cancer

Advanced Science, EarlyView.
sEVs‐circ6718 serves as a promising serum biomarker for gastric cancer early diagnosis and prognosis, promoting malignant transformation in gastric cancer cells and GC‑MSC differentiation into CAFs. sEVs‑circ6718 holds potential as a biomarker for the early diagnosis and prognostic assessment of gastric cancer.
Fan Zhang, Xueyan Zang, Dongli Wang, Rong Li, Hui Qian, Wenrong Xu, Jiajia Jiang, Yongmin Yan   +7 more
wiley   +1 more source

Trans amplifying mRNA vaccine expressing consensus spike elicits broad neutralization of SARS CoV 2 variants

npj Vaccines
SARS-CoV-2 continues to evolve and evade vaccine immunity necessitating vaccines that offer broad protection across variants. Conventional mRNA vaccines face cost and scalability challenges, prompting the exploration of alternative platforms like trans ...
Abhinay Gontu, Sougat Misra, Shubhada K. Chothe, Santhamani Ramasamy, Padmaja Jakka, Maurice Byukusenge, Lindsey C. LaBella, Meera Surendran Nair, Bhushan M. Jayarao, Marco Archetti, Ruth H. Nissly, Suresh V. Kuchipudi   +11 more
doaj   +1 more source

ヒラメの獲得免疫制御に及ぼすサイトカインの影響 [PDF]

, 2015
東京海洋大学博士学位論文 平成25年度(2013) 応用生命科学 課程博士 甲第304号指導教員: 近藤秀裕全文公表年月日: 2018-05 ...
Taechavasonyoo Apichaya
core   +1 more source

In vivo analysis of staphylococcus aureus-infected mice reveals differential temporal and spatial expression patterns of fhuD2 [PDF]

, 2017
Staphylococcus aureus is an opportunistic human pathogen and a major cause of invasive infections such as bacteremia, endocarditis, pneumonia and wound infections.
Bacconi, Marta, Bagnoli, Fabio, Bensi, Giuliano, Chiarot, Emiliano, Delany, Isabel, Donato, Paolo, Freitag, Nancy E., Haag, Andreas F.   +7 more
core   +1 more source

Tumor‐Derived Exosomes Deliver Membrane‐Bound Fgl2 to Activate FcγRIIB‐Mediated Immunosuppression in Myeloid‐Derived Suppressor Cells

Advanced Science, EarlyView.
This study reveals that the Fgl2‐FcγRIIB signaling axis is a key mechanism by which MDSCs mediate tumor immune evasion. Tumor‐derived exosomes systemically activate MDSCs via this pathway, positioning this axis as a promising broad‐spectrum target for cancer immunotherapy.
Fenglin Lin, Dingqin Cai, Chunli Jian, Yaxian Qi, Linpeng Zheng, Qiao Yang, Longyao Zhang, Diangang Chen, Lingchen Li, Ping Cai, Lingyou Sun, Luping Zhang, Jianguo Sun   +12 more
wiley   +1 more source

Leveraging Artificial Intelligence and Large Language Models for Cancer Immunotherapy

Advanced Science, EarlyView.
Cancer immunotherapy faces challenges in predicting treatment responses and understanding resistance mechanisms. Artificial intelligence (AI) and machine learning (ML) offer powerful solutions for cancer immunotherapy in patient stratification, biomarker discovery, treatment strategy optimization, and foundation model development.
Xinchao Wu, Mengtao Sun, Lusheng Li, Jieqiong Wang, Shibiao Wan   +4 more
wiley   +1 more source

A gorilla adenovirus-based vaccine against Zika virus induces durable immunity and confers protection in pregnancy [PDF]

, 2019
The teratogenic potential of Zika virus (ZIKV) has made the development of an effective vaccine a global health priority. Here, we generate two gorilla adenovirus-based ZIKV vaccines that encode for pre-membrane (prM) and envelope (E) proteins (GAd-Zvp ...
Brough, Douglas E, Curiel, David T, Diamond, Michael S, Dmitriev, Igor P, Fremont, Daved H, Hassan, Ahmed O, Kashentseva, Elena A, Zhao, Haiyan   +7 more
core   +1 more source

Genome wide expression profiling reveals suppression of host defence responses during colonisation by Neisseria meningitides but not N. lactamica. [PDF]

, 2011
Both Neisseria meningitidis and the closely related bacterium Neisseria lactamica colonise human nasopharyngeal mucosal surface, but only N. meningitidis invades the bloodstream to cause potentially life-threatening meningitis and septicaemia.
Hibberd, Martin L, Kroll, J Simon, Langford, Paul R, Li, Ming-Shi, Wong, Hazel En En   +4 more
core   +1 more source

Individualized, heterologous chimpanzee adenovirus and self-amplifying mRNA neoantigen vaccine for advanced metastatic solid tumors: phase 1 trial interim results [PDF]

, 2022
Christine D. Palmer, Amy Rappaport, Matthew J. Davis, Meghan G. Hart, Ciaran D. Scallan, Sue‐Jean Hong, Leonid Gitlin, Lauren D. Kraemer, Sonia Kounlavouth, Aaron Yang, Lindsey Smith, Desiree Schenk, Mojca Škoberne, Kiara Taquechel, Martina Marrali, Jason R. Jaroslavsky, Charmaine N. Nganje, Elizabeth Maloney, Rita Zhou, Daniel Navarro-Gomez, Adrienne C. Greene, Gijsbert M. Grotenbreg, Renee L. Greer, Wade Blair, Minh Duc Cao, Shawn Chan, Kyounghwa Bae, Alexander I. Spira, Sameek Roychowdhury, David P. Carbone, Brian S. Henick, Charles G. Drake, Benjamin Solomon, Daniel H. Ahn, Amit Mahipal, Steve Maron, Benny Johnson, Raphaël F. Rousseau, Roman Yelensky, Chih‐Yi Liao, Daniel V.T. Catenacci, Andrew M. Allen, Andrew R. Ferguson, Karin Jooss   +43 more
openalex   +1 more source