Results 31 to 40 of about 199,785 (356)
mRNA Vaccine Platform: mRNA Production and Delivery
Russian Journal of Bioorganic Chemistry, 2023 Vaccination is the most efficient way to prevent infectious diseases. mRNA-based vaccines is a new approach to vaccine development, which have several very useful advantages over other types of vaccines. Since mRNA encodes only the target antigen there is no potential risk of infection as in the case with attenuated or inactivated pathogens.
Litvinova, V. R. +3 more
openaire +2 more sources
Neutralizing Potency of Prototype and Omicron RBD mRNA Vaccines Against Omicron Variant
Frontiers in Immunology, 2022 The newly emerged Omicron variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) contains more than 30 mutations on the spike protein, 15 of which are located within the receptor binding domain (RBD).
Jinkai Zang +8 more
doaj +1 more source
Mapping of transcription termination within the S segment of SFTS phlebovirus facilitated the generation of NSs-deletant viruses [PDF]
, 2017 SFTS phlebovirus (severe fever with thrombocytopenia syndrome virus; SFTSV) is an emerging tick-borne bunyavirus that was first reported in China in 2009. Here we report the generation of a recombinant SFTSV (rHB29NSsKO) that cannot express the viral non-
Brennan, Benjamin +2 more
core +1 more source
Myocarditis following COVID‐19 mRNA (mRNA‐1273) vaccination
Clinical Case Reports, 2022 AbstractIn this case report, we presented a case of myocarditis as a rare complication that developed after Covid mRNA‐1273 vaccine. Cases of post‐vaccine myocarditis usually progress with mild symptoms. However, it should be a situation that healthcare workers should keep in mind, that myocarditis may develop after vaccination.
Suresh Babu Chellapandian +4 more
openaire +3 more sources
Delivery Strategies for mRNA Vaccines [PDF]
Pharmaceutical Medicine, 2022 The therapeutic potential for messenger RNA (mRNA) in infectious diseases and cancer was first realized almost three decades ago, but only in 2018 did the first lipid nanoparticle-based small interfering RNA (siRNA) therapy reach the market with the United States Food and Drug Administration (FDA) approval of patisiran (Onpattro™) for hereditary ATTR ...
Sivakumar Ramachandran +2 more
openaire +2 more sources
Demystifying mRNA vaccines: an emerging platform at the forefront of cryptic diseases
RNA Biology, 2022 Messenger RNA (mRNA) vaccines have been studied for decades, but only recently, during the COVID-19 pandemic, has the technology garnered noteworthy attention.
Nusrat Zahan Rouf +4 more
doaj +1 more source
OVERVIEW ON MRNA VACCINES BEYOND COVID-19
International Journal of Infectious Diseases, 2023 COVID-19 mRNA vaccines: COVID-19 pandemic has made an extraordinary impact on global vaccine technology platform developments. Never in human history have there at least 6 vaccine platforms including: inactivated, protein subunit, VLP and other 3 new ...
Kiat Ruxrungtham
doaj +1 more source
RNA Vaccine: novel approach for cancer treatment [PDF]
, 2011 Cancer is still an unsolved puzzle and a major cause of mortality and morbidity in the world. Today, about one in every thousand people is dying due to cancer. No effective agent has yet been found which can cure cancer in its metastatic stage.
Kanika Bhalla +2 more
core +2 more sources
Frontiers in Immunology, 2022 Immunogenicity of HIV-1 mRNA vaccine regimens was analyzed in a non-human primate animal model. Rhesus macaques immunized with mRNA in lipid nanoparticle (mRNA/LNP) formulation expressing HIV-1 Gag and Gag conserved regions (CE) as immunogens developed ...
Antonio Valentin +17 more
doaj +1 more source
Platelets, 2022 In 2021, the world experienced the most extensive vaccination campaign to defeat COVID-19. Many cases of idiopathic thrombocytopenia have been reported following injections of SARS-Cov-2 mRNA vaccine.
Mathilde Chanut +7 more
doaj +1 more source