Results 11 to 20 of about 1,693,659 (204)
Vaccines, 2021 Increases in the world’s population and population density promote the spread of emerging pathogens. Vaccines are the most cost-effective means of preventing this spread. Traditional methods used to identify and produce new vaccines are not adequate, in most instances, to ensure global protection.
Frank Kowalzik +5 more
openaire +3 more sources
Frontiers in Public Health, 2023 IntroductionEpidemiological modeling is widely used to offer insights into the COVID-19 pandemic situation in Asia. We reviewed published computational (mathematical/simulation) models conducted in Asia that assessed impacts of pharmacological and non ...
Karan Thakkar +6 more
doaj +1 more source
In Vitro Transcribed RNA-Based Platform Vaccines: Past, Present, and Future
Vaccines, 2023 mRNA was discovered in 1961, but it was not used as a vaccine until after three decades. Recently, the development of mRNA vaccine technology gained great impetus from the pursuit of vaccines against COVID-19.
Alexey D. Perenkov +3 more
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Research Advances on the Stability of mRNA Vaccines
Viruses, 2023 Compared to other vaccines, the inherent properties of messenger RNA (mRNA) vaccines and their interaction with lipid nanoparticles make them considerably unstable throughout their life cycles, impacting their effectiveness and global accessibility.
Feiran Cheng +7 more
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mRNA vaccine-elicited antibodies to SARS-CoV-2 and circulating variants
Nature, 2021 Here we report on the antibody and memory B cell responses of a cohort of 20 volunteers who received the Moderna (mRNA-1273) or Pfizer–BioNTech (BNT162b2) vaccine against SARS-CoV-21–4. Eight weeks after the second injection of vaccine, volunteers showed
Zijun Wang +33 more
semanticscholar +1 more source
BNT162b2 mRNA Covid-19 Vaccine in a Nationwide Mass Vaccination Setting
New England Journal of Medicine, 2021 Background As mass vaccination campaigns against coronavirus disease 2019 (Covid-19) commence worldwide, vaccine effectiveness needs to be assessed for a range of outcomes across diverse populations in a noncontrolled setting.
Noa Dagan +9 more
semanticscholar +1 more source
ACS Nano, 2021 Lipid nanoparticles (LNPs) have emerged across the pharmaceutical industry as promising vehicles to deliver a variety of therapeutics. Currently in the spotlight as vital components of the COVID-19 mRNA vaccines, LNPs play a key role in effectively ...
Rumiana Tenchov +3 more
semanticscholar +1 more source
Industrial Psychiatry Journal, 2021 “Necessity is the mother of invention:” An adage was brought to life with the emergence of the mRNA vaccine against the backdrop of the foreboding and mercurial COVID-19 pandemic. Considering a negligible adverse-effect profile and a break-neck manufacturing speed, it shone bright as the ideal vaccine candidate.
Tahoora Ali +4 more
openaire +3 more sources
An mRNA Vaccine against SARS-CoV-2 — Preliminary Report
New England Journal of Medicine, 2020 Background The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in late 2019 and spread globally, prompting an international effort to accelerate development of a vaccine.
L. Jackson +32 more
semanticscholar +1 more source
Emergence of mRNA vaccines in the management of cancer
Expert Review of Vaccines, 2023 Introduction mRNA vaccines have been developed as a promising cancer management. It is noted that specification of the antigen sequence of the target antigen is necessary for the design and manufacture of an mRNA vaccine. Areas covered The steps involved
Mohamad Irfan Mohamad Razif +8 more
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