Results 21 to 30 of about 203,318 (355)
In Gratitude for mRNA Vaccines
New England Journal of Medicine, 2021 mRNA Vaccine Research and the Lasker–DeBakey Award Although the production time (11 months) of the messenger RNA vaccines against SARS-CoV-2 infection set a record, the preclinical research undergi...
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The advances of adjuvants in mRNA vaccines
npj Vaccines, 2023 AbstractThe remarkable success of messenger RNA (mRNA) vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has propelled the rapid development of this vaccination technology in recent years. Over the last three decades, numerous studies have shown the considerable potential of mRNA vaccines that elicit protective immune ...
Chunyuan Xie, Ruhui Yao, Xiaojun Xia
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OVERVIEW ON MRNA VACCINES BEYOND COVID-19
International Journal of Infectious Diseases, 2023 COVID-19 mRNA vaccines: COVID-19 pandemic has made an extraordinary impact on global vaccine technology platform developments. Never in human history have there at least 6 vaccine platforms including: inactivated, protein subunit, VLP and other 3 new ...
Kiat Ruxrungtham
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Demystifying mRNA vaccines: an emerging platform at the forefront of cryptic diseases
RNA Biology, 2022 Messenger RNA (mRNA) vaccines have been studied for decades, but only recently, during the COVID-19 pandemic, has the technology garnered noteworthy attention.
Nusrat Zahan Rouf +4 more
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Identification of a novel splice variant form of the influenza A virus M2 ion channel with an antigenically distinct ectodomain [PDF]
, 2012 Segment 7 of influenza A virus produces up to four mRNAs. Unspliced transcripts encode M1, spliced mRNA2 encodes the M2 ion channel, while protein products from spliced mRNAs 3 and 4 have not previously been identified.
Digard, Paul +12 more
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mRNA Vaccines against Flaviviruses [PDF]
Vaccines, 2021 Numerous vaccines have now been developed using the mRNA platform. In this approach, mRNA coding for a viral antigen is in vitro synthesized and injected into the host leading to exogenous protein expression and robust immune responses. Vaccines can be rapidly developed utilizing the mRNA platform in the face of emerging pandemics.
Clayton J. Wollner, Justin M. Richner
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Frontiers in Immunology, 2022 Immunogenicity of HIV-1 mRNA vaccine regimens was analyzed in a non-human primate animal model. Rhesus macaques immunized with mRNA in lipid nanoparticle (mRNA/LNP) formulation expressing HIV-1 Gag and Gag conserved regions (CE) as immunogens developed ...
Antonio Valentin +17 more
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Platelets, 2022 In 2021, the world experienced the most extensive vaccination campaign to defeat COVID-19. Many cases of idiopathic thrombocytopenia have been reported following injections of SARS-Cov-2 mRNA vaccine.
Mathilde Chanut +7 more
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Vaccines, 2021 The mRNA-based vaccine approach is a promising alternative to traditional vaccines due to its ability for prompt development, high potency, and potential for secure administration and low-cost production.
Md. Motiar Rahman +2 more
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A Comprehensive Review of mRNA Vaccines
International Journal of Molecular Sciences, 2023 mRNA vaccines have been demonstrated as a powerful alternative to traditional conventional vaccines because of their high potency, safety and efficacy, capacity for rapid clinical development, and potential for rapid, low-cost manufacturing. These vaccines have progressed from being a mere curiosity to emerging as COVID-19 pandemic vaccine front ...
Vrinda Gote +6 more
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