Results 21 to 30 of about 192,514 (206)

Myocarditis following COVID‐19 mRNA (mRNA‐1273) vaccination

open access: yesClinical Case Reports, 2022
AbstractIn this case report, we presented a case of myocarditis as a rare complication that developed after Covid mRNA‐1273 vaccine. Cases of post‐vaccine myocarditis usually progress with mild symptoms. However, it should be a situation that healthcare workers should keep in mind, that myocarditis may develop after vaccination.
Suresh Babu Chellapandian   +4 more
openaire   +3 more sources

RNA Vaccine: novel approach for cancer treatment [PDF]

open access: yes, 2011
Cancer is still an unsolved puzzle and a major cause of mortality and morbidity in the world. Today, about one in every thousand people is dying due to cancer. No effective agent has yet been found which can cure cancer in its metastatic stage.
Kanika Bhalla   +2 more
core   +2 more sources

Delivery Strategies for mRNA Vaccines [PDF]

open access: yesPharmaceutical Medicine, 2022
The therapeutic potential for messenger RNA (mRNA) in infectious diseases and cancer was first realized almost three decades ago, but only in 2018 did the first lipid nanoparticle-based small interfering RNA (siRNA) therapy reach the market with the United States Food and Drug Administration (FDA) approval of patisiran (Onpattro™) for hereditary ATTR ...
Sivakumar Ramachandran   +2 more
openaire   +2 more sources

Neutralizing Potency of Prototype and Omicron RBD mRNA Vaccines Against Omicron Variant

open access: yesFrontiers in Immunology, 2022
The newly emerged Omicron variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) contains more than 30 mutations on the spike protein, 15 of which are located within the receptor binding domain (RBD).
Jinkai Zang   +8 more
doaj   +1 more source

Demystifying mRNA vaccines: an emerging platform at the forefront of cryptic diseases

open access: yesRNA Biology, 2022
Messenger RNA (mRNA) vaccines have been studied for decades, but only recently, during the COVID-19 pandemic, has the technology garnered noteworthy attention.
Nusrat Zahan Rouf   +4 more
doaj   +1 more source

OVERVIEW ON MRNA VACCINES BEYOND COVID-19

open access: yesInternational Journal of Infectious Diseases, 2023
COVID-19 mRNA vaccines: COVID-19 pandemic has made an extraordinary impact on global vaccine technology platform developments. Never in human history have there at least 6 vaccine platforms including: inactivated, protein subunit, VLP and other 3 new ...
Kiat Ruxrungtham
doaj   +1 more source

The Transcriptional Landscape of Marek’s Disease Virus in Primary Chicken B Cells Reveals Novel Splice Variants and Genes [PDF]

open access: yes, 2019
Marek’s disease virus (MDV) is an oncogenic alphaherpesvirus that infects chickens and poses a serious threat to poultry health. In infected animals, MDV efficiently replicates in B cells in various lymphoid organs.
Bertzbach, Luca D.   +7 more
core   +2 more sources

Comparative immunogenicity of an mRNA/LNP and a DNA vaccine targeting HIV gag conserved elements in macaques

open access: yesFrontiers in Immunology, 2022
Immunogenicity of HIV-1 mRNA vaccine regimens was analyzed in a non-human primate animal model. Rhesus macaques immunized with mRNA in lipid nanoparticle (mRNA/LNP) formulation expressing HIV-1 Gag and Gag conserved regions (CE) as immunogens developed ...
Antonio Valentin   +17 more
doaj   +1 more source

Advances in mRNA vaccines

open access: yes, 2022
mRNA vaccines have been increasingly recognized as a powerful vaccine platform since the FDA approval of two COVID-19 mRNA vaccines, which demonstrated outstanding prevention efficacy as well as great safety profile. Notably, nucleoside modification and lipid nanoparticle-facilitated delivery has greatly improved the immunogenicity, stability, and ...
Li, Mengyun   +3 more
openaire   +2 more sources

Successful mRNA SARS-Cov-2 vaccine rechallenge after a first episode of immune thrombocytopenic purpura

open access: yesPlatelets, 2022
In 2021, the world experienced the most extensive vaccination campaign to defeat COVID-19. Many cases of idiopathic thrombocytopenia have been reported following injections of SARS-Cov-2 mRNA vaccine.
Mathilde Chanut   +7 more
doaj   +1 more source

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